Fra‐1 substitutes for c‐Fos in AP‐1‐mediated signal transduction in retinal apoptosis
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References (22)
The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation
1991 • 3,396 citations
A CBP Integrator Complex Mediates Transcriptional Activation and AP-1 Inhibition by Nuclear Receptors
1996 • 2,183 citations
Antitumor promotion and antiinflammation: Down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone
1990 • 1,605 citations
Transcriptional interference between c-Jun and the glucocorticoid receptor: Mutual inhibition of DNA binding due to direct protein-protein interaction
1990 • 1,583 citations
Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor
1990 • 1,272 citations
Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation
1999 • 676 citations
Fra-1 replaces c-Fos-dependent functions in mice
2000 • 464 citations
The absence of c-fos prevents light-induced apoptotic cell death of photoreceptors in retinal degeneration in vivo
1997 • 350 citations
CBP-induced stimulation of c-Fos activity is abrogated by E1A.
1995 • 342 citations
The product of a fos-related gene, fra-1, binds cooperatively to the AP-1 site with Jun: transcription factor AP-1 is comprised of multiple protein complexes.
1989 • 318 citations
Inhibition of AP-1 by the Glucocorticoid-inducible Protein GILZ
2001 • 293 citations
Mutual transrepression of Fos and the glucocorticoid receptor: involvement of a functional domain in Fos which is absent in FosB.
1990 • 290 citations
Apoptotic cell death in retinal degenerations
1998 • 242 citations
Steroid Receptor Coactivator-1 Coactivates Activating Protein-1-mediated Transactivations through Interaction with the c-Jun and c-Fos Subunits
1998 • 205 citations
Fos is a preferential target of glucocorticoid receptor inhibition of AP-1 activity in vitro.
1993 • 167 citations
c-fosControls the “Private Pathway” of Light-Induced Apoptosis of Retinal Photoreceptors
2000 • 142 citations
Gene expression in the mouse retina: the effect of damaging light.
2000 • 130 citations
Glucocorticoids Antagonize Ap-1 by Inhibiting the Activation/Phosphorylation of Jnk without Affecting Its Subcellular Distribution
2000 • 115 citations
Prevention of photoreceptor apoptosis by activation of the glucocorticoid receptor.
2001 • 105 citations
Glucocorticoid Repression of AP-1 Is Not Mediated by Competition for Nuclear Coactivators
2001 • 93 citations
Differential DNA binding activities of the transcription factors AP-1 and Oct-1 during light-induced apoptosis of photoreceptors
1999 • 48 citations
AP-1 mediated retinal photoreceptor apoptosis is independent of N-terminal phosphorylation of c-Jun
2001 • 38 citations