c-fosControls the “Private Pathway” of Light-Induced Apoptosis of Retinal Photoreceptors

Mitochondria and Apoptosis

1998 • 8,909 citations

Caspases: Enemies Within

1998 • 6,923 citations

Induction of Apoptotic Program in Cell-Free Extracts: Requirement for dATP and Cytochrome c

1996 • 5,133 citations

The Release of Cytochrome c from Mitochondria: A Primary Site for Bcl-2 Regulation of Apoptosis

1997 • 4,728 citations

The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation

1991 • 3,396 citations

Programmed Cell Death in Animal Development

1997 • 2,690 citations

The Beaver Dam Eye Study

1992 • 1,362 citations

Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization

1998 • 1,226 citations

Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo.

1995 • 1,179 citations

Bcl-2 inhibits the mitochondrial release of an apoptogenic protease.

1996 • 1,143 citations

Mitochondrial permeability transition is a central coordinating event of apoptosis.

1996 • 857 citations

The central executioners of apoptosis: caspases or mitochondria?

1998 • 772 citations

Hsp70 exerts its anti-apoptotic function downstream of caspase-3-like proteases

1998 • 692 citations

Apoptotic photoreceptor cell death in mouse models of retinitis pigmentosa.

1994 • 630 citations

Cell death during differentiation of the retina in the mouse

1984 • 531 citations

Sunlight and Age-Related Macular Degeneration

1993 • 397 citations

Cytochrome c activation of CPP32-like proteolysis plays a critical role in a Xenopus cell-free apoptosis system

1997 • 388 citations

c-Fos transcriptional activity stimulated by H-Ras-activated protein kinase distinct from JNK and ERK

1994 • 350 citations

The absence of c-fos prevents light-induced apoptotic cell death of photoreceptors in retinal degeneration in vivo

1997 • 350 citations

Disease sequence from mutant rhodopsin allele to rod and cone photoreceptor degeneration in man

1998 • 262 citations

Apoptotic cell death in retinal degenerations

1998 • 242 citations

Programmed cell death is a universal feature of embryonic and postnatal neuroproliferative regions throughout the central nervous system

1998 • 236 citations

Protein kinase A and AP-1 (c-Fos/JunD) are induced during apoptosis of mouse mammary epithelial cells.

1994 • 180 citations

Apoptosis in neurodegenerative disorders

1997 • 171 citations

C57BL/6J Mice With inherited Retinal Degeneration

1974 • 169 citations

The postnatal development of the retina in the normal and rodless CBA mouse: A light and electron microscopic study

1972 • 164 citations

Phosphoproteome dynamics reveal novel ERK1/2 MAP kinase substrates with broad spectrum of functions

2013 • 146 citations

Light-induced Apoptosis: Differential Timing in the Retina and Pigment Epithelium

1997 • 134 citations

Programmed Cell Death in the Developing Nervous System

1996 • 120 citations

Photic injury triggers apoptosis of photoreceptor cells.

1996 • 110 citations

Cell death in the development of the human retina: phagocytosis of pyknotic and apoptotic bodies by retinal cells

1986 • 108 citations

Alkylation-induced apoptosis of embryonic stem cells in which the gene for DNA-repair, methyltransferase, had been disrupted by gene targeting

1997 • 95 citations

Molecular and clinical aspects of apoptosis

1996 • 83 citations

A general role for c-Fos in cellular protection against DNA-damaging carcinogens and cytostatic drugs.

1997 • 77 citations

Increased susceptibility to constant light in nr and pcd mice with inherited retinal degenerations.

1999 • 72 citations

N-methyl-N-nitrosourea-induced photoreceptor apoptosis in the mouse retina.

1996 • 70 citations

Role of O6-methylguanine-DNA methyltransferase in the resistance of pancreatic tumors to DNA alkylating agents.

1997 • 58 citations

Insulin stimulates phosphorylation of c-Jun, c-Fos, and Fos-related proteins in cultured adipocytes.

1994 • 53 citations

Induction of c-fos, c-jun, junB and junD mRNA and AP-1 by alkylating mutagens in cells deficient and proficient for the DNA repair protein O6-methylguanine-DNA methyltransferase (MGMT) and its relationship to cell death, mutation induction and chromosomal instability.

1996 • 49 citations

Morphologic characteristics of N‐methyi ‐N‐nitrosourea‐induced retinal degeneration in C₅₇BL mice

1997 • 49 citations

Differential DNA binding activities of the transcription factors AP-1 and Oct-1 during light-induced apoptosis of photoreceptors

1999 • 48 citations

C-Fos Is Not Essential for Apoptosis

1996 • 45 citations

Transcription Factor Activation during Signal-induced Apoptosis of Immature CD4+CD8+ Thymocytes

1997 • 41 citations

Retinal Degeneration Induced by N-Methyl-N-Nitrosourea and Detection of 7-Methyldeoxyguanosine in the Rat Retina

1993 • 40 citations

The retina of c-fos-/- mice: electrophysiologic, morphologic and biochemical aspects.

2000 • 39 citations

Retinal degeneration in the rd mouse in the absence of c-fos.

1998 • 39 citations

Apoptosis during castration-induced regression of the prostate is Fos dependent

1998 • 32 citations

Investigating retinitis pigmentosa: a laboratory scientist's perspective

1997 • 27 citations

The Proto-oncogene c-fos Mediates Apoptosis in Murine T-Lymphocytes Induced by Ionizing Radiation and Dexamethasone

1997 • 25 citations

Light-Induced Apoptosis in the Rat Retina in Vivo

1995 • 23 citations

A simple and stable d.c.electrode for ocular electrophysiology.

1998 • 10 citations