Ca²⁺ mobilization in physiologically stimulated single T cells gradually increases with peptide concentration (analog signaling)

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

Inositol trisphosphate and calcium signalling

1993 • 6,546 citations

T-cell antigen receptor genes and T-cell recognition

1988 • 3,099 citations

Emptying of intracellular Ca2+ stores releases a novel small messenger that stimulates Ca2+ influx

1993 • 892 citations

T cell antigen receptor signal transduction: A tale of tails and cytoplasmic protein-tyrosine kinases

1993 • 552 citations

The T Cell Receptor as a Multicomponent Signalling Machine: CD4/CD8 Coreceptors and CD45 in T Cell Activation

1992 • 539 citations

Quantitation of antigen-presenting cell MHC class II/peptide complexes necessary for T-cell stimulation

1990 • 468 citations

The Minimal Number of Class II MHC-Antigen Complexes Needed for T Cell Activation

1990 • 410 citations

Mitogen-induced oscillations of cytosolic Ca2+ and transmembrane Ca2+ current in human leukemic T cells.

1989 • 402 citations

Beta 2-integrin LFA-1 signaling through phospholipase C-gamma 1 activation.

1993 • 185 citations

Idiotope‐specific T cell clones that recognize syngeneic immunoglobulin fragments in the context of class II molecules

1986 • 178 citations

Calcium fluxes in T lymphocytes.

1992 • 133 citations

Calcium oscillations in human T and natural killer cells depend upon membrane potential and calcium influx.

1993 • 110 citations

Imaging early steps of human T cell activation by antigen-presenting cells.

1992 • 108 citations

Costimulation of T cell receptor/CD3-mediated activation of resting human CD4+ T cells by leukocyte function-associated antigen-1 ligand intercellular cell adhesion molecule-1 involves prolonged inositol phospholipid hydrolysis and sustained increase of intracellular Ca2+ levels.

1992 • 106 citations

Signal transduction by T-cell receptors: mobilization of Ca and regulation of Ca-dependent effector molecules

1992 • 105 citations

Differential regulatory effects of intercellular adhesion molecule-1 on costimulation by the CD28 counter-receptor B7.

1992 • 78 citations

Minimum length of an idiotypic peptide and a model for its binding to a major histocompatibility complex class II molecule.

1989 • 76 citations

Molecular Regulation of the IL‐2 Gene: Rheostatic Control of the Immune System

1993 • 64 citations

Synthetic peptides and β‐chain gene rearrangements reveal a diversified T cell repertoire for a λ light chain third hypervariable region

1986 • 61 citations

Topology and affinity of T-cell receptor mediated recognition of peptide—MHC complexes

1993 • 57 citations

Anti-CD3-stimulated Ca2+ signal in individual human peripheral T cells. Activation correlates with a sustained increase in intracellular Ca2+1.

1993 • 46 citations

Quantal release of Ca ²⁺ from intracellular stores by InsP ₃ : tests of the concept of control of Ca ²⁺ release by intraluminal Ca ²⁺

1991 • 39 citations

Thapsigargin reveals evidence for fMLP-insensitive calcium pools in human leukocytes

1992 • 31 citations

Idiotype‐Specific, Major Histocompatibility Complex Restricted T Cells are of both Th1 and Th2 Type

1991 • 20 citations

Spectrofluorimetric and image recordings of spontaneous and lectin-induced cytosolic calcium oscillations in Jurkat T cells

1991 • 20 citations

Calcium signals in single T cells on activation by lectin

1991 • 10 citations

Recognition of the Self Idiotype by T Cells: Induction of a Rapid Increase in Cytoplasmic Free Calcium in T Cells Recognizing a Variable L Chain Determinant

1992 • 1 citations