Spectrofluorimetric and image recordings of spontaneous and lectin-induced cytosolic calcium oscillations in Jurkat T cells

A new generation of Ca2+ indicators with greatly improved fluorescence properties.

1985 • 21,873 citations

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

Inositol trisphosphate, a novel second messenger in cellular signal transduction

1984 • 6,088 citations

Inositol phosphates and cell signalling

1989 • 4,058 citations

Contingent Genetic Regulatory Events in T Lymphocyte Activation

1989 • 1,108 citations

Primary structure and functional expression of the inositol 1,4,5-trisphosphate-binding protein P400

1989 • 1,039 citations

T-cell mitogens cause early changes in cytoplasmic free Ca2+ and membrane potential in lymphocytes

1982 • 1,026 citations

Studies of Inositol Phospholipid-Specific Phospholipase C

1989 • 914 citations

THE PROTEIN KINASE C FAMILY: HETEROGENEITY AND ITS IMPLICATIONS

1989 • 739 citations

Cytosolic calcium oscillators

1988 • 690 citations

Minimal model for signal-induced Ca2+ oscillations and for their frequency encoding through protein phosphorylation.

1990 • 626 citations

The T Cell Receptor

1987 • 554 citations

Free cytoplasmic calcium concentration and the mitogenic stimulation of lymphocytes.

1983 • 466 citations

Simulated calcium current can both cause calcium loading in and trigger calcium release from the sarcoplasmic reticulum of a skinned canine cardiac Purkinje cell.

1985 • 445 citations

Fluorescence ratio imaging: a new window into intracellular ionic signaling

1986 • 421 citations

Repetitive spikes in cytoplasmic calcium evoked by histamine in human endothelial cells

1988 • 412 citations

Mitogen-induced oscillations of cytosolic Ca2+ and transmembrane Ca2+ current in human leukemic T cells.

1989 • 402 citations

Two roles for guanine nucleotides in the stimulus-secretion sequence of neutrophils

1986 • 339 citations

Pulsatile intracellular calcium release does not depend on fluctuations in inositol trisphosphate concentration

1989 • 338 citations

Oscillations of cytosolic Ca2+ in pituitary cells due to action potentials

1987 • 331 citations

Protein kinase C — a family affair

1989 • 289 citations

Agonist-induced oscillations in cytoplasmic free calcium concentration in single rat hepatocytes

1987 • 271 citations

Structure, Function, and Serology of the T-Cell Antigen Receptor Complex

1987 • 264 citations

Localization and heterogeneity of agonist-induced changes in cytosolic calcium concentration in single bovine adrenal chromaffin cells from video imaging of fura-2.

1989 • 236 citations

Transmembrane Ion Fluxes during Activation of Human T Lymphocytes: Role of Ca²⁺, Na⁺/H⁺ Exchange and Phospholipid Turnover

1987 • 154 citations

Functional and Molecular Aspects of Human T Lymphocyte Activation via T3‐Ti and Tl1 Pathways

1987 • 152 citations

Oscillations of free cytosolic calcium evoked by cholinergic and catecholaminergic agonists in rat parotid acinar cells.

1988 • 147 citations

Transmembrane Signals and Intracellular “Second Messengers” in the Regulation of Quiescent B‐Lymphocyte Activation

1987 • 137 citations

Intracellular free calcium and mitosis in mammalian cells: anaphase onset is calcium modulated, but is not triggered by a brief transient.

1989 • 119 citations

T-Cell Activation

1986 • 102 citations

The T11 glycoprotein is functionally linked to a calcium channel in precursor and mature T-lineage cells.

1986 • 98 citations

Calcium oscillations in non-excitable cells

1989 • 94 citations

Antigen-dependent increase in cytosolic free calcium in specific human T-lymphocyte clones

1985 • 92 citations

Signal Transduction in Human T Lymphocytes

1987 • 89 citations

The T-cell antigen receptor regulates sustained increases in cytoplasmic free Ca2+ through extracellular Ca2+ influx and ongoing intracellular Ca2+ mobilization

1987 • 87 citations

Crosslinkage of B lymphocyte surface immunoglobulin by anti-Ig or antigen induces prolonged oscillation of intracellular ionized calcium.

1987 • 82 citations

Calcium oscillations in single adrenal glomerulosa cells stimulated by angiotensin II.

1988 • 73 citations

Uptake of extracellular Ca²⁺ and not recruitment from internal stores is essential for T lymphocyte proliferation

1988 • 72 citations

Spatially resolved cytosolic calcium response to angiotensin II and potassium in rat glomerulosa cells measured by digital imaging techniques.

1987 • 71 citations

Spontaneous oscillations in cytoplasmic calcium concentration in vascular smooth muscle

1989 • 37 citations

The Somatotrope: an Endocrine Cell With Functional Calcium Transients

1988 • 37 citations

Molecular signaling mechanisms in T-lymphocyte activation pathways: A review and future prospects

1987 • 34 citations

Cytosolic free calcium oscillates in single bovine adrenal glomerulosa cells in response to angiotensin II stimulation

1989 • 33 citations

Signal transducing mechanisms involved in human T cell activation via surface T44 molecules. Comparison with signals transduced via the T cell receptor complex

1986 • 28 citations

Characterization of Ca2+ and K+ currents in the human Jurkat T cell line: effects of phytohaemagglutinin.

1989 • 27 citations

Lectin Interactions With the Jurkat Leukemic T-Cell Line: Quantitative Binding Studies and Interleukin-2 Production

1988 • 15 citations

T Cells, the MHC, and Function

1984 • 14 citations