Idiotope‐specific T cell clones that recognize syngeneic immunoglobulin fragments in the context of class II molecules

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Antigen-specific interaction between T and B cells

1985 • 1,396 citations

Antigen-Presenting Function of the Macrophage

1984 • 1,164 citations

Properties of Monoclonal Antibodies to Mouse Ig Allotypes, H-2, and Ia Antigens

1979 • 993 citations

T-Lymphocyte Recognition of Antigen in Association with Gene Products of the Major Histocompatibility Complex

1985 • 942 citations

Properties and Applications of Monoclonal Antibodies Directed against Determinants of the Thy-1 Locus

1979 • 595 citations

Fine Specificity Analysis with Monoclonal Antibodies of Antigens Controlled by the Major Histocompatibility Complex and by the Qa/TL Region in Mice

1979 • 451 citations

Antigen presentation by hapten-specific B lymphocytes. I. Role of surface immunoglobulin receptors.

1984 • 422 citations

Evidence implicating L3T4 in class II MHC antigen reactivity; monoclonal antibody GK1.5 (anti-L3T4a) blocks class II MHC antigen-specific proliferation, release of lymphokines, and binding by cloned murine helper T lymphocyte lines.

1983 • 377 citations

A rat anti-mouse T4 monoclonal antibody (H129.19) inhibits the proliferation of Ia-reactive T cell clones and delineates two phenotypically distinct (T4+, Lyt-2,3-, and T4-, Lyt-2,3+) subsets among anti-Ia cytolytic T cell clones.

1984 • 308 citations

Idiotype‐specific T helper cells are required to induce idiotype‐positive B memory cells to secrete antibody

1978 • 268 citations

Antigen-reactive T cell clones. I. Transcomplementing hybrid I-A-region gene products function effectively in antigen presentation.

1980 • 252 citations

Ia-restricted encephalitogenic T lymphocytes mediating EAE lyse autoantigen-presenting astrocytes

1986 • 214 citations

Autoimmune-Like Antibodies to the Ligand-Binding Sites of Myeloma Proteins

1971 • 213 citations

Clones of Killer and Helper T Cells: Growth Requirements, Specificity and Retention of Function in Long‐Term Culture

1980 • 206 citations

Affinity labeling of a mouse myeloma protein which binds nitrophenyl ligands. Kinetics of labeling and isolation of a labeled peptide

1970 • 181 citations

Cloned helper T cells can kill B lymphoma cells in the presence of specific antigen: Ia restriction and cognate vs. noncognate interactions in cytolysis

1984 • 152 citations

Active antibody fragment (Fv) composed of the variable portions of heavy and light chains

1973 • 151 citations

Construction and properties of new Lyt-congenic strains and anti-Lyt-2.2 and anti-Lyt-3.1 monoclonal antibodies

1980 • 136 citations

Gene transfer of H-2 class II genes: Antigen presentation by mouse fibroblast and hamster B-cell lines

1984 • 135 citations

Differentiation of thymocytes in fetal organ culture: analysis of phenotypic changes accompanying the appearance of cytolytic and interleukin 2-producing cells.

1984 • 131 citations

Recognition of immunoglobulin idiotypes by thymus-derived lymphocytes.

1975 • 120 citations

Induction of antiphosphorylcholine antibody formation by anti-idiotypic antibodies.

1975 • 119 citations

Immune response gene function correlates with the expression of an Ia antigen. II. A quantitative deficiency in A(e):E(a), complex expression causes a corresponding defect in antigen-presenting cell function

1982 • 115 citations

Mice whose B cells cannot produce the T15 idiotype also lack an antigen-specific helper T cell required for T15 expression.

1979 • 102 citations

Membrane Ia expression and antigen-presenting accessory cell function of L cells transfected with class II major histocompatibility complex genes.

1984 • 95 citations

Requirements for the processing of antigen by antigen-presenting B cells. II. Biochemical comparison of the fate of antigen in B cell tumors and macrophages.

1982 • 93 citations

Absence of an antigen‐specific helper T cell required for the expression of the Tn 15 idiotype in mice treated with anti‐μ antibody

1980 • 92 citations

The complete nucleotide sequence of the I-Eα^dimmune response gene

1983 • 90 citations

T cell development in B cell-deficient mice. IV. The role of B cells as antigen-presenting cells in vivo.

1986 • 88 citations

The fine specificity of regulatory T cells IV. Idiotypic complementarity and antigen‐bridging interactions in the anti‐lysozyme response

1979 • 77 citations

Production of auto-anti-idiotypic antibody during the normal immune response to TNP-ficoll. III. Absence in nu/nu mice: evidence for T-cell dependence of the anti-idiotypic-antibody response.

1979 • 68 citations

Synthetic peptides and β‐chain gene rearrangements reveal a diversified T cell repertoire for a λ light chain third hypervariable region

1986 • 61 citations

Antigen-specific helper T cells required for dominant idiotype expression are not H-2 restricted

1981 • 55 citations

Helper T cell recognition of the variable domains of a mouse myeloma protein (315). Effect of the major histocompatibility complex and domain conformation.

1982 • 54 citations

T helper cell recognition of idiotopes on λ2 light chains of M315 and T952: evidence for dependence on somatic mutations in the third hypervariable region

1985 • 51 citations

Specificity of T and B lymphocytes for myeloma protein 315

1977 • 49 citations

Role of antigen-specific B cells in the induction of SRBC-specific T cell proliferation.

1984 • 48 citations

H–2-linked genes control immune response to V-domains of myeloma protein 315

1980 • 38 citations

Lymphocyte specificity to protein antigens V. Conformational dependence of activation of cytochrome c-specific T cells

1982 • 33 citations

T helper cells recognize an idiotope located on peptide 88-114/117 of the light chain variable domain of an isologous myeloma protein (315).

1983 • 32 citations

Idiotypes and Anti-idiotypes as Probes in Analysis of Immunoregulation

1977 • 30 citations

Regulatory idiotopes. Induction of idiotype-recognizing helper T cells by free light and heavy chains.

1984 • 28 citations

Gene complementation in the T lymphocyte proliferative response to poly(Glu⁵⁶Lys³⁵Phe⁹)_nFunctional evidence for a restriction element coded for by both the I‐A and I‐E subregions

1980 • 27 citations

Recognition of λ1 and λ2 murine light chains by carrierspecific isologous T helper cells; effect of L‐H chain assembly

1983 • 23 citations

Recognition of a naturally occurring idiotype by autologous T cells

1977 • 23 citations

Sperm-specific surface antigenicity common to seven animal phyla

1980 • 19 citations

Mouse myeloma proteins with lambda 2 and lambda 3 light chains.

1981 • 18 citations

H‐2‐Linked Ir Genes Have a Striking Influence on the Immunogenicity of Idiotopes of Myeloma Protein 315 for T Helper Cells

1985 • 12 citations

Amino acid sequence diversity in mouse lambda 2 variable regions.

1984 • 12 citations

Dominant suppressive effect of the silent E allele on an in vivo T helper cell response under E E region‐linked immune response gene control

1985 • 8 citations

Helper T cell requirements for T15 idiotype expression on phosphorylcholine‐specific antibodies

1985 • 6 citations

Influence of helper T cells on the expression of a murine intrastrain crossreactive idiotype.

1986 • 4 citations

H-2 and non-H-2 genes complement each other for a carrier (idiotype)-specific Th response

1984 • 4 citations