Post-transcriptional Regulation of Erythropoietin mRNA Stability by Erythropoietin mRNA-binding Protein

mRNA stability in mammalian cells

1995 • 1,258 citations

Oxygen sensing and molecular adaptation to hypoxia

1996 • 1,187 citations

Erythropoietin: structure, control of production, and function

1992 • 1,158 citations

Transcriptional Regulation of the Rat Vascular Endothelial Growth Factor Gene by Hypoxia

1995 • 1,087 citations

Role of the Kidney in Erythropoiesis

1957 • 873 citations

Post-transcriptional Regulation of Vascular Endothelial Growth Factor by Hypoxia

1996 • 639 citations

Hypoxia-induced Transcriptional Activation and Increased mRNA Stability of Vascular Endothelial Growth Factor in C6 Glioma Cells

1995 • 608 citations

Similarities between the oxygen-sensing mechanisms regulating the expression of vascular endothelial growth factor and erythropoietin.

1994 • 584 citations

Reverse transcription and DNA amplification by a Thermus thermophilus DNA polymerase

1991 • 475 citations

The regulated expression of erythropoietin by two human hepatoma cell lines.

1987 • 374 citations

Regulation of the erythropoietin gene

1993 • 310 citations

Hypoxia increases rate of transcription and stability of tyrosine hydroxylase mRNA in pheochromocytoma (PC12) cells.

1994 • 264 citations

Liver as the primary site of erythropoietin formation in the fetus.

1977 • 219 citations

Hypoxic induction of the human erythropoietin gene: cooperation between the promoter and enhancer, each of which contains steroid receptor response elements.

1992 • 211 citations

Erythropoietin mRNA levels are governed by both the rate of gene transcription and posttranscriptional events

1991 • 202 citations

In vivo and in vitro regulation of erythropoietin mRNA: measurement by competitive polymerase chain reaction

1993 • 198 citations

Murine erythropoietin gene: cloning, expression, and human gene homology.

1986 • 193 citations

Cloning, sequencing, and evolutionary analysis of the mouse erythropoietin gene.

1986 • 153 citations

Studies on the Production of Erythropoietin by Isolated Perfused Organs

1961 • 132 citations

Hypoxia, a Novel Inducer of Acute Phase Gene Expression in a Human Hepatoma Cell Line

1995 • 119 citations

Hypoxia up-regulates the activity of a novel erythropoietin mRNA binding protein.

1991 • 117 citations

Characterization of the Hypoxia-inducible Protein Binding Site within the Pyrimidine-rich Tract in the 3′-Untranslated Region of the Tyrosine Hydroxylase mRNA

1996 • 103 citations

Hypoxia stimulates binding of a cytoplasmic protein to a pyrimidine-rich sequence in the 3'-untranslated region of rat tyrosine hydroxylase mRNA

1994 • 95 citations

A radioimmunoassay for erythropoietin: serum levels in normal human subjects and patients with hemopoietic disorders.

1982 • 94 citations

Development of a new radioimmunoassay for erythropoietin using recombinant erythropoietin

1990 • 64 citations

Enhancement by hypoxia of human erythropoietin gene transcription in vitro.

1990 • 59 citations

Enhanced erythropoietin secretion in hepatoblastoma cells in response to hypoxia

1989 • 42 citations

Renal biogenesis of erythropoietin

1975 • 34 citations

Use of a Marked Erythropoietin Gene for Investigation of Its Cis-acting Elements

1995 • 31 citations

Comparison of the human and mouse erythropoietin genes shows extensive homology in the flanking regions

1993 • 29 citations