Characterization of the Hypoxia-inducible Protein Binding Site within the Pyrimidine-rich Tract in the 3′-Untranslated Region of the Tyrosine Hydroxylase mRNA

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

1986 • 4,200 citations

Splicing of Messenger RNA Precursors

1987 • 919 citations

Cloning and domain structure of the mammalian splicing factor U2AF

1992 • 566 citations

Distinct Binding Specificities and Functions of Higher Eukaryotic Polypyrimidine Tract-Binding Proteins

1995 • 537 citations

Identification and purification of a 62,000-dalton protein that binds specifically to the polypyrimidine tract of introns.

1989 • 349 citations

Oligopyrimidine tract at the 5' end of mammalian ribosomal protein mRNAs is required for their translational control.

1991 • 342 citations

hnRNP 1, the polyprimidine tract-binding protein: distinct nuclear localization and association with hnRNAs

1992 • 299 citations

Characterization and primary structure of the poly(C)-binding heterogeneous nuclear ribonucleoprotein complex K protein.

1992 • 281 citations

Translation of 15-lipoxygenase mRNA is inhibited by a protein that binds to a repeated sequence in the 3′ untranslated region.

1994 • 267 citations

Hypoxia increases rate of transcription and stability of tyrosine hydroxylase mRNA in pheochromocytoma (PC12) cells.

1994 • 264 citations

Selection of splice sites in pre-mRNAs with short internal exons.

1991 • 224 citations

Functional dissection of a mouse ribosomal protein promoter: significance of the polypyrimidine initiator and an element in the TATA-box region.

1990 • 151 citations

A mutational analysis of the polypyrimidine tract of introns. Effects of sequence differences in pyrimidine tracts on splicing

1993 • 146 citations

Ribonucleoprotein particles in cellular processes.

1988 • 123 citations

Hypoxia up-regulates the activity of a novel erythropoietin mRNA binding protein.

1991 • 117 citations

The complete sequence of the rabbit erythroid cell-specific 15-lipoxygenase mRNA: comparison of the predicted amino acid sequence of the erythrocyte lipoxygenase with other lipoxygenases

1989 • 103 citations

Hypoxia stimulates binding of a cytoplasmic protein to a pyrimidine-rich sequence in the 3'-untranslated region of rat tyrosine hydroxylase mRNA

1994 • 95 citations

A regulatory cis element and a specific binding factor involved in the mitogenic control of murine ribosomal protein L32 translation.

1992 • 94 citations

Characterization of RNA binding specificity of theDrosophilasex-lethal protein byin vitroligand selection

1994 • 57 citations

Polypyrimidine tracts and their binding proteins: Regulatory sites for posttranscriptional modulation of gene expression

1993 • 50 citations

Hybridization and dissociation rates of phosphodiester or modified oligodeoxynucleotides with RNA at nearphysiological conditions.

1991 • 29 citations

Adaptations of neurotransmitter synthesis to chronic hypoxia in cell culture

1987 • 28 citations

A rapid method for site-specific mutagenesis using larger plasmids as templates.

1993 • 17 citations