Hypoxia stimulates binding of a cytoplasmic protein to a pyrimidine-rich sequence in the 3'-untranslated region of rat tyrosine hydroxylase mRNA

A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

1986 • 4,200 citations

Iron-Responsive Elements: Regulatory RNA Sequences That Control mRNA Levels and Translation

1988 • 707 citations

Cytoplasmic protein binds in vitro to a highly conserved sequence in the 5' untranslated region of ferritin heavy- and light-subunit mRNAs.

1988 • 684 citations

B. TYROSINE HYDROXYLASE

1966 • 493 citations

Identification and purification of a 62,000-dalton protein that binds specifically to the polypyrimidine tract of introns.

1989 • 349 citations

Oligopyrimidine tract at the 5' end of mammalian ribosomal protein mRNAs is required for their translational control.

1991 • 342 citations

Characterization and molecular cloning of polypyrimidine tract-binding protein: a component of a complex necessary for pre-mRNA splicing.

1991 • 338 citations

hnRNP 1, the polyprimidine tract-binding protein: distinct nuclear localization and association with hnRNAs

1992 • 299 citations

Characterization and primary structure of the poly(C)-binding heterogeneous nuclear ribonucleoprotein complex K protein.

1992 • 281 citations

REGULATED mRNA STABILITY

1990 • 279 citations

Hypoxia increases rate of transcription and stability of tyrosine hydroxylase mRNA in pheochromocytoma (PC12) cells.

1994 • 264 citations

Selection of splice sites in pre-mRNAs with short internal exons.

1991 • 224 citations

The adenosine-uridine binding factor recognizes the AU-rich elements of cytokine, lymphokine, and oncogene mRNAs.

1991 • 222 citations

Regulation of Tyrosine Hydroxylase Gene Expression in the Rat Carotid Body by Hypoxia

1992 • 186 citations

Isolation and characterization of the human tyrosine hydroxylase gene: identification of 5' alternative splice sites responsible for multiple mRNAs

1987 • 160 citations

Ribonucleoprotein particles in cellular processes.

1988 • 123 citations

Hypoxia up-regulates the activity of a novel erythropoietin mRNA binding protein.

1991 • 117 citations

A regulatory cis element and a specific binding factor involved in the mitogenic control of murine ribosomal protein L32 translation.

1992 • 94 citations

Organization and evolution of the rat tyrosine hydroxylase gene

1987 • 73 citations

Regulation of mRNA stability and its relevance to disease.

1991 • 66 citations

EFFECTS OF HYPOXIA ON TYROSINE HYDROXYLASE ACTIVITY IN RAT CAROTID BODY

1979 • 57 citations

Polypyrimidine tracts and their binding proteins: Regulatory sites for posttranscriptional modulation of gene expression

1993 • 50 citations

Coenzymes and hydroxylases: ascorbate and dopamine-beta-hydroxylase; tetrahydropteridines and phenylalanine and tyrosine hydroxylases.

1966 • 49 citations

Induction of tyrosine 3-monooxygenase in carotid body of rats exposed to hypoxic conditions

1977 • 36 citations

Hybridization and dissociation rates of phosphodiester or modified oligodeoxynucleotides with RNA at nearphysiological conditions.

1991 • 29 citations

Adaptations of neurotransmitter synthesis to chronic hypoxia in cell culture

1987 • 28 citations