Interleukin‐6 is a direct mediator of T cell migration

Principles of interleukin (IL)-6-type cytokine signalling and its regulation

2003 • 3,098 citations

Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway

1998 • 2,072 citations

Choice of STATs and Other Substrates Specified by Modular Tyrosine-Based Motifs in Cytokine Receptors

1995 • 992 citations

IL-6 in autoimmune disease and chronic inflammatory proliferative disease

2002 • 793 citations

IL-6: a regulator of the transition from neutrophil to monocyte recruitment during inflammation

2002 • 759 citations

Two Signals Are Necessary for Cell Proliferation Induced by a Cytokine Receptor gp130: Involvement of STAT3 in Anti-Apoptosis

1996 • 661 citations

Dancing to the tune of chemokines

2001 • 624 citations

Stat3 Activation Is Responsible for IL-6-Dependent T Cell Proliferation Through Preventing Apoptosis: Generation and Characterization of T Cell-Specific Stat3-Deficient Mice

1998 • 571 citations

Keratinocyte-specific ablation of Stat3 exhibits impaired skin remodeling, but does not affect skin morphogenesis

1999 • 521 citations

IL-6-Deficient Mice Are Resistant to Experimental Autoimmune Encephalomyelitis: Roles of IL-6 in the Activation and Differentiation of Autoreactive T Cells

1998 • 448 citations

Protein-tyrosine Phosphatase Shp-2 Regulates Cell Spreading, Migration, and Focal Adhesion

1998 • 390 citations

IL-6-deficient mice resist myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis

1998 • 307 citations

Proliferation of adult T cell leukemia/lymphoma cells is associated with the constitutive activation of JAK/STAT proteins

1997 • 278 citations

A monoclonal antibody against an activation epitope on mouse integrin chain beta 1 blocks adhesion of lymphocytes to the endothelial integrin alpha 6 beta 1.

1993 • 270 citations

Complexity and specificity of integrin signalling

2000 • 244 citations

Regulation of Early Events in Integrin Signaling by Protein Tyrosine Phosphatase SHP-2

1999 • 219 citations

Interleukin 6 inhibits proliferation and, in cooperation with an epidermal growth factor receptor autocrine loop, increases migration of T47D breast cancer cells.

2001 • 190 citations

Interleukin 6 decreases cell-cell association and increases motility of ductal breast carcinoma cells.

1989 • 158 citations

Interleukin‐6 functions in autoimmune encephalomyelitis: a study in gene‐targeted mice

1998 • 156 citations

Interleukin-6 functions in autoimmune encephalomyelitis: a study in gene-targeted mice

1998 • 143 citations

Soluble Human Interleukin‐6 Receptor

1995 • 96 citations

Interleukin 6 promotes epithelial migration by a fibronectin‐dependent mechanism

1992 • 94 citations

The Cytoplasmic Tyrosine Motifs in Full-Length Glycoprotein 130 Have Different Roles in IL-6 Signal Transduction

2000 • 93 citations

Morphogenetic movements at gastrulation require the SH2 tyrosine phosphatase Shp2

1999 • 90 citations

STAT3 Deficiency in Keratinocytes Leads to Compromised Cell Migration through Hyperphosphorylation of p130

2002 • 58 citations

Response of human NK cells to IL-6 alterations of the cell surface phenotype, adhesion to fibronectin and laminin, and tumor necrosis factor-alpha/beta secretion.

1993 • 51 citations

Induction of in vitro human lymphocyte migration by interleukin 3, interleukin 4, and interleukin 6

1990 • 44 citations

Cytokine Signaling through Stat3 Activates Integrins, Promotes Adhesion, and Induces Growth Arrest in the Myeloid Cell Line 32D

2000 • 43 citations

Interleukin-1 is a motility factor for human breast carcinoma cells in vitro: additive effect with interleukin-6.

1992 • 32 citations

Tumor‐derived transforming growth factor‐β1 and interleukin‐6 are chemotactic for lymphokine‐activated killer cells

1994 • 19 citations

Chemoattractive effect on the effector cells of the supernatants from melanoma cells transfected with the interleukin-2 (IL-2), IL-4 or IL-6 gene

1998 • 4 citations