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The leucine-rich repeat: a versatile binding motif

Data up to Jan 2025

Published1994
Citations1,209
References38

Total Citations Per Year

Abstract

References (38)

X-Ray Structure of the GCN4 Leucine Zipper, a Two-Stranded, Parallel Coiled Coil

1991 • 1,433 citations

The Toll gene of drosophila, required for dorsal-ventral embryonic polarity, appears to encode a transmembrane protein

1988 • 1,077 citations

Entry of L. monocytogenes into cells is mediated by internalin, a repeat protein reminiscent of surface antigens from gram-positive cocci

1991 • 823 citations

Functional dissection of the HIV-1 Rev trans-activator—Derivation of a trans-dominant repressor of Rev function

1989 • 742 citations

The nerve growth factor family of receptors

1992 • 649 citations

Crystal structure of porcine ribonuclease inhibitor, a protein with leucine-rich repeats

1993 • 614 citations

slit: an extracellular protein necessary for development of midline glia and commissural axon pathways contains both EGF and LRR domains.

1990 • 499 citations

Three-dimensional structure of the alkaline protease of Pseudomonas aeruginosa: a two-domain protein with a calcium binding parallel beta roll motif.

1993 • 468 citations

New Domain Motif: the Structure of Pectate Lyase C, a Secreted Plant Virulence Factor

1993 • 450 citations

Amino-terminal leucine-rich repeats in gonadotropin receptors determine hormone selectivity.

1991 • 330 citations

Connectin: A homophilic cell adhesion molecule expressed on a subset of muscles and the motoneurons that innervate them in Drosophila

1992 • 282 citations

RAD1, an excision repair gene of Saccharomyces cerevisiae, is also involved in recombination.

1988 • 209 citations

Developing relationships: arterial platelet adhesion, glycoprotein Ib, and leucine-rich glycoproteins

1991 • 205 citations

S. pombe gene sds22+ essential for a midmitotic transition encodes a leucine-rich repeat protein that positively modulates protein phosphatase-1

1991 • 191 citations

Lipopolysaccharide-induced protein tyrosine phosphorylation in human macrophages is mediated by CD14.

1993 • 177 citations

Small proteoglycans

1993 • 166 citations

GRR1 of Saccharomyces cerevisiae is required for glucose repression and encodes a protein with leucine-rich repeats.

1991 • 165 citations

The oligodendrocyte-myelin glycoprotein belongs to a distinct family of proteins and contains the HNK-1 carbohydrate.

1990 • 151 citations

The TMK1 gene from Arabidopsis codes for a protein with structural and biochemical characteristics of a receptor protein kinase.

1992 • 149 citations

Structure of the Luteinizing Hormone Receptor Gene and Multiple Exons of the Coding Sequence*

1991 • 146 citations

Drosophila chaoptin, a member of the leucine-rich repeat family, is a photoreceptor cell-specific adhesion molecule.

1990 • 140 citations

Human biglycan gene. Putative promoter, intron-exon junctions, and chromosomal localization

1991 • 136 citations

Mitotic regulation of protein phosphatases by the fission yeast sds22 protein

1993 • 129 citations

The yopM gene of Yersinia pestis encodes a released protein having homology with the human platelet surface protein GPIb alpha

1989 • 123 citations

Point mutation in a leucine-rich repeat of platelet glycoprotein Ib alpha resulting in the Bernard-Soulier syndrome.

1993 • 114 citations

Structure and Action of Mammalian Ribonuclease (Angiogenin) Inhibitor

1993 • 102 citations

The deduced protein sequence of the human carboxypeptidase N high molecular weight subunit reveals the presence of leucine-rich tandem repeats.

1990 • 94 citations

Molecular Cloning of a Novel Bone-Forming Compound: Osteoinductive Factor

1990 • 90 citations

RAD7 gene of Saccharomyces cerevisiae: transcripts, nucleotide sequence analysis, and functional relationship between the RAD7 and RAD23 gene products.

1986 • 71 citations

A leucine‐rich repeat peptide derived from the Drosophila Toll receptor forms extended filaments with a β‐sheet structure

1991 • 70 citations

Structural and functional analyses of Saccharomyces cerevisiae wild-type and mutant RNA1 genes.

1989 • 65 citations

The trypanosome VSG expression site encodes adenylate cyclase and a leucine-rich putative regulatory gene.

1991 • 63 citations

Amphipathic beta structure of a leucine-rich repeat peptide.

1991 • 62 citations

Towards understanding the glycoprotein hormone receptors

1991 • 56 citations

The CCR4 protein from Saccharomyces cerevisiae contains a leucine-rich repeat region which is required for its control of ADH2 gene expression.

1992 • 54 citations

Leucine periodicity of U2 small nuclear ribonucleoprotein particle (snRNP) A' protein is implicated in snRNP assembly via protein-protein interactions.

1991 • 46 citations

Ribosome-binding protein p34 is a member of the leucine-rich-repeat-protein superfamily

1993 • 34 citations

Evidence that the Rad1 and Rad10 proteins of Saccharomyces cerevisiae participate as a complex in nucleotide excision repair of UV radiation damage

1993 • 14 citations

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The leucine-rich repeat: a versatile binding motif (1994) – Trends in Biochemical Sciences | Metascience Observatory Explorer