A Domain of p47phox That Interacts with Human Neutrophil Flavocytochrome b558

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Active Oxygen Species and the Functions of Phagocytic Leukocytes

1980 • 1,124 citations

Subcellular localization of the b-cytochrome component of the human neutrophil microbicidal oxidase: translocation during activation.

1983 • 938 citations

[15] Libraries of peptides and proteins displayed on filamentous phage

1993 • 770 citations

Regulation of Phagocyte Oxygen Radical Production by the GTP-Binding Protein Rac 2

1991 • 669 citations

The biochemical basis of the NADPH oxidase of phagocytes

1993 • 631 citations

Purified cytochrome b from human granulocyte plasma membrane is comprised of two polypeptides with relative molecular weights of 91,000 and 22,000.

1987 • 459 citations

Two cytosolic components of the human neutrophil respiratory burst oxidase translocate to the plasma membrane during cell activation.

1990 • 435 citations

Two Cytosolic Neutrophil Oxidase Components Absent in Autosomal Chronic Granulomatous Disease

1988 • 401 citations

Cloning of a 67-kD Neutrophil Oxidase Factor with Similarity to a Noncatalytic Region of p60 ^c-src

1990 • 393 citations

Cytochrome b ₅₅₈ : the Flavin-Binding Component of the Phagocyte NADPH Oxidase

1992 • 384 citations

Neutrophil nicotinamide adenine dinucleotide phosphate oxidase assembly. Translocation of p47-phox and p67-phox requires interaction between p47-phox and cytochrome b558.

1991 • 379 citations

Cytochrome b-245 is a flavocytochrome containing FAD and the NADPH-binding site of the microbicidal oxidase of phagocytes

1992 • 351 citations

The phosphorylation of the respiratory burst oxidase component p47phox during neutrophil activation. Phosphorylation of sites recognized by protein kinase C and by proline-directed kinases.

1994 • 342 citations

Recombinant 47-Kilodalton Cytosol Factor Restores NADPH Oxidase in Chronic Granulomatous Disease

1989 • 341 citations

Translocation of Rac correlates with NADPH oxidase activation. Evidence for equimolar translocation of oxidase components.

1993 • 316 citations

Cloning of the cDNA and functional expression of the 47-kilodalton cytosolic component of human neutrophil respiratory burst oxidase.

1989 • 310 citations

p40phox, a third cytosolic component of the activation complex of the NADPH oxidase to contain src homology 3 domains

1993 • 295 citations

Molecular basis of chronic granulomatous disease [see comments]

1991 • 290 citations

The electron transport chain of the microbicidal oxidase of phagocytic cells and its involvement in the molecular pathology of chronic granulomatous disease.

1989 • 286 citations

Role of Src homology 3 domains in assembly and activation of the phagocyte NADPH oxidase.

1994 • 286 citations

Assembly of the phagocyte NADPH oxidase: binding of Src homology 3 domains to proline-rich targets.

1994 • 285 citations

Rac translocates independently of the neutrophil NADPH oxidase components p47phox and p67phox. Evidence for its interaction with flavocytochrome b558.

1994 • 260 citations

Phosphorylation of neutrophil 47-kDa cytosolic oxidase factor. Translocation to membrane is associated with distinct phosphorylation events.

1990 • 248 citations

Association of a Ras-related protein with cytochrome b of human neutrophils

1989 • 248 citations

The Human Neutrophil Respiratory Burst Oxidase

1990 • 225 citations

Molecular basis of chronic granulomatous disease [see comments]

1991 • 210 citations

Activation of neutrophil leukocytes: chemoattractant receptors and respiratory burst ¹

1993 • 184 citations

A possible role for protein phosphorylation in the activation of the respiratory burst in human neutrophils. Evidence from studies with cells from patients with chronic granulomatous disease.

1986 • 168 citations

Topological Mapping of Neutrophil Cytochrome b Epitopes with Phage-display Libraries

1995 • 162 citations

An SH3 domain and proline-rich sequence mediate an interaction between two components of the phagocyte NADPH oxidase complex.

1994 • 160 citations

The cytosolic components of the respiratory burst oxidase exist as a M(r) approximately 240,000 complex that acquires a membrane-binding site during activation of the oxidase in a cell-free system.

1992 • 150 citations

Mapping sites of interaction of p47-phox and flavocytochrome b with random-sequence peptide phage display libraries.

1995 • 148 citations

The Respiratory Burst Oxidase and the Molecular Genetics of Chronic Granulomatous Disease

1993 • 130 citations

A point mutation in gp91-phox of cytochrome b558 of the human NADPH oxidase leading to defective translocation of the cytosolic proteins p47-phox and p67-phox.

1994 • 109 citations

Function of wild-type or mutant Rac2 and Rap1a GTPases in differentiated HL60 cell NADPH oxidase activation

1995 • 109 citations

156Pro-->Gln substitution in the light chain of cytochrome b558 of the human NADPH oxidase (p22-phox) leads to defective translocation of the cytosolic proteins p47-phox and p67-phox.

1994 • 107 citations

Activated or dominant inhibitory mutants of Rap1A decrease the oxidative burst of Epstein-Barr virus-transformed human B lymphocytes.

1994 • 96 citations

Dissociation of Rac translocation from p47phox/p67phox movements in human neutrophils by tyrosine kinase inhibitors

1995 • 93 citations

The phagocyte 47-kilodalton cytosolic oxidase protein is an early reactant in activation of the respiratory burst.

1990 • 89 citations

Purification and characterization of a third cytosolic component of the superoxide-generating NADPH oxidase of macrophages.

1991 • 78 citations

Direct evidence for interaction between COOH-terminal regions of cytochrome b558 subunits and cytosolic 47-kDa protein during activation of an O(2-)-generating system in neutrophils.

1992 • 78 citations

Evidence for a readily dissociable complex of p47phox and p67phox in cytosol of unstimulated human neutrophils.

1994 • 70 citations

Continuous phosphorylation of both the 47 and the 49 kDa proteins occurs during superoxide production by neutrophils

1990 • 66 citations

The translocation of respiratory burst oxidase components from cytosol to plasma membrane is regulated by guanine nucleotides and diacylglycerol.

1992 • 61 citations

Functional domain in an arginine-rich carboxyl-terminal region of p47phox.

1993 • 60 citations

Characterization of the NADPH-dependent superoxide production activated by sodium dodecyl sulfate in a cell-free system of pig neutrophils

1987 • 58 citations

Inhibition of NADPH oxidase activation by synthetic peptides mapping within the carboxyl-terminal domain of small GTP-binding proteins. Lack of amino acid sequence specificity and importance of polybasic motif.

1994 • 56 citations

Inhibition of neutrophil NADPH oxidase assembly by a myristoylated pseudosubstrate of protein kinase C.

1993 • 43 citations

Cytosolic oxidase factors in the NADPH‐dependent oxidase of human neutrophils

1993 • 30 citations

[48] Purification of human neutrophil NADPH oxidase cytochrome b-558 and association with Rap 1A

1995 • 22 citations