The relative importance of dopamine and norepinephrine in mediating locomotor activity

Multiple receptors for dopamine

1979 • 3,739 citations

From motivation to action: Functional interface between the limbic system and the motor system

1980 • 2,292 citations

Postsynaptic Supersensitivity after 6‐Hydroxy‐dopamine Induced Degeneration of the Nigro‐striatal Dopamine System

1971 • 1,922 citations

Amphetamine and apomorphine responses in the rat following 6-OHDA lesions of the nucleus accumbens septi and corpus striatum

1975 • 1,741 citations

Central Catecholamine Neuron Systems: Anatomy and Physiology of the Norepinephrine and Epinephrine Systems

1979 • 1,361 citations

Advances in biochemical psychopharmacology

1970 • 1,186 citations

Antischizophrenic Drugs: Chronic Treatment Elevates Dopamine Receptor Binding in Brain

1977 • 1,017 citations

Amphetamines and related compounds

1971 • 979 citations

The Structure and Function of Nervous Tissue

1972 • 905 citations

Role of Transmitter Uptake Mechanisms in Synaptic Neurotransmission

1971 • 768 citations

Selective 60HDA-induced destruction of mesolimbic dopamine neurons: Abolition of psychostimulant-induced locomotor activity in rats

1976 • 706 citations

The pharmacological and anatomical substrates of the amphetamine response in the rat

1975 • 583 citations

Effects of chemical stimulation of the mesolimbic dopamine system upon locomotor activity

1976 • 564 citations

The biological properties of the optical isomers of propranolol and their effects on cardiac arrhythmias

1968 • 562 citations

An animal behavior model for studying central serotonergic synapses

1976 • 555 citations

Evidence for a central noradrenaline receptor stimulation by clonidine

1970 • 550 citations

Dopamine ?Autoreceptors?: Pharmacological characterization by microiontophoretic single cell recording studies

1977 • 544 citations

Depletion of brain noradrenaline and dopamine by 6‐hydroxydopamine

1971 • 535 citations

Dopamine Auto- and Postsynaptic Receptors: Electrophysiological Evidence for Differential Sensitivity to Dopamine Agonists

1979 • 502 citations

Stimulation of locomotor activity following injection of dopamine into the nucleus accumbens

1973 • 477 citations

Antiamphetamine effects following inhibition of tyrosine hydroxylase.

1966 • 445 citations

Cocaine and Other Stimulants

1977 • 421 citations

Norepinephrine-Dopamine Interactions and Behavior

1977 • 411 citations

Selective Brain Dopamine Depletion in Developing Rats: An Experimental Model of Minimal Brain Dysfunction

1976 • 400 citations

Functional Role of the Nigro‐Neostriatal Dopamine Neurons*)

1966 • 394 citations

Fiber Connections of the Basal Ganglia

1979 • 387 citations

Blockage of amphetamine induced motor stimulation and stereotypy in the adult rat following neonatal treatment with 6-hydroxydopamine

1973 • 350 citations

Morphological and Functional Aspects of Central Monoamine Neurons

1970 • 349 citations

Functional Studies of the Central Catecholamines

1982 • 344 citations

The locomotion of the acute spinal cat injected with clonidine i.v.

1973 • 341 citations

Inhibition of d-amphetamine-induced locomotor activity by injection of haloperidol into the nucleus accumbens of the rat

1975 • 332 citations

L-Dopa: Effect on Concentrations of Dopamine, Norepinephrine, and Serotonin in Brains of Mice

1970 • 332 citations

Direct chemical stimulation of dopaminergic mechanisms in the neostriatum of the rat

1969 • 331 citations

A functional effect of dopamine in the nucleus accumbens and in some other dopamine-rich parts of the rat brain

1975 • 323 citations

Long-Term Changes in Dopaminergic Innervation of Caudate Nucleus After Continuous Amphetamine Administration

1978 • 320 citations

Catecholamine receptor agonists

1976 • 318 citations

Specificity of 6-hydroxydopamine induced degeneration of central monoamine neurones: An electron and fluorescence microscopic study with special reference to intracerebral injection on the nigro-striatal dopamine system

1973 • 295 citations

Receptor Adaptations to Centrally Acting Drugs

1981 • 293 citations

Somatosensory inattention after dopamine-depleting intracerebral 6-OHDA injections: Spontaneous recovery and pharmacological control

1979 • 279 citations

The rotating rodent: A two component system?

1978 • 276 citations

Motor effects of serotonin in the central nervous system

1980 • 259 citations

Ascending catecholamine pathways and amphetamine-induced locomotor activity: Importance of dopamine and apparent non-involvement of norepinephrine

1975 • 259 citations

ehavioural evidence for supersensitivtiy of postsynaptic dopamine receptors in the mesolimbic system after chronic administration of desipramine

1981 • 239 citations

3-PPP, a new centrally acting DA-receptor agonist with selectivity for autoreceptors

1981 • 229 citations

Stereotyped behaviour patterns and hyperactivity induced by amphetamine and apomorphine after discrete 6-hydroxydopamine lesions of extrapyramidal and mesolimbic nuclei

1977 • 225 citations

The Role of Brain Dopamine in Behavioral Regulation and the Actions of Psychotropic Drugs

1970 • 216 citations

Differential regional development of tolerance to increase in dopamine turnover upon repeated neuroleptic administration

1977 • 212 citations

Dopamine and noradrenaline receptor stimulation: Reversal of reserpine-induced suppression of motor activity

1973 • 210 citations

Daily fluctuation (circadian and ultradian) in biogenic amines of the rat brain

1968 • 206 citations

Serotonergic inhibition of catecholamine-induced behavioral arousal

1973 • 200 citations

Classification of neuroleptic drugs according to their ability to inhibit apomorphine-induced locomotion and gnawing: Evidence for two different mechanisms of action

1978 • 198 citations

Age-related Changes in the Nigrostriatum: A Behavioral and Biochemical Analysis

1978 • 197 citations

Inhibitory effect of gammahydroxybutyric acid and gammaaminobutyric acid on the dopamine cells in the substantia nigra

1973 • 193 citations

The mechanisms of action of L-dopa in Parkinson's disease

1974 • 193 citations

Chronic treatment with antidepressants prevents the inhibitory effect of small doses of apomorphine on dopamine synthesis and motor activity

1979 • 193 citations

Cholinergic Mechanism in Brain inhibiting Amphetamine‐induced Stereotyped Behaviour

1968 • 187 citations

The relative importance of dopaminergic and noradrenergic neuronal systems for the stimulation of locomotor activity induced by amphetamine and other drugs

1973 • 184 citations

Differentiation of the dopamine mechanisms mediating stereotyped behaviour and hyperactivity in the nucleus accumbens and caudate-putamen

1977 • 179 citations

Pharmacological evidence for a stimulation of dopamine neurons by noradrenaline neurons in the brain

1976 • 179 citations

Effects of amphetamine on the turnover rate of brain catecholamines and motor activity

1972 • 178 citations

Decrease of cerebral 5-hydroxytryptamine by 3,4-dihydroxyphenylalanine after inhibition of extracerebral decarboxylase

1968 • 177 citations

Behavioral and biochemical effects ofl-DOPA after peripheral decarboxylase inhibition

1969 • 171 citations

The behavioural effects of dopamine applied intracerebrally to areas of the mesolimbic system

1975 • 167 citations

Stereotype hyperactive behaviour produced by dopamine in the absence of noradrenaline

1967 • 167 citations

Changes in dopamine levels in the corpus striatum following lesions in the substantia nigra

1969 • 161 citations

The effect of para-chlorophenylalanine on spontaneous locomotor activity in the rat

1971 • 159 citations

Some effects of propranolol on the central nervous system

1965 • 159 citations

EVIDENCE FOR INVOLVEMENT OF 5‐HYDROXYTRYPTAMINE IN THE ACTIONS OF AMPHETAMINE

1974 • 158 citations

Quantitative aspects of normal locomotion in rats

1979 • 158 citations

On the significance of central noradrenaline for motor activity: Experiments with a new dopamine β-hydroxylase inhibitor

1969 • 156 citations

dl-5-Hydroxytryptophan-induced changes in central monoamine neurons after peripheral decarboxylase inhibition

1971 • 155 citations

The decarboxylation of amino acids related to tyrosine and their awakening action in reserpine‐treated mice

1960 • 154 citations

Non-specific histopathological changes induced by the intracerebral injection of 6-hydroxy-dopamine (6-OH-DA)

1972 • 149 citations

Behavioral and neurochemical effects of lesions in the raphe system of the rat.

1971 • 146 citations

Behavioral, biochemical, and histochemical analyses of the central effects of monoamine precursors after peripheral decar☐ylase inhibition

1972 • 142 citations

Mode of Action of Psychomotor Stimulant Drugs

1970 • 139 citations

Serotoninergic modulation of the dopamine response from the nucleus accumbens

1976 • 138 citations

Psychopharmacology of Affective Disorders

1980 • 138 citations

Age-dependent effects of 6-hydroxydopamine on locomotor activity in the rat

1979 • 137 citations

Behavioral, physiological, and neurochemical changes after 6-hydroxydopamine-induced degeneration of the nigro-striatal dopamine neurons.

1974 • 135 citations

Comparison of tyrosine hydroxylase and dopamine-?-hydroxylase inhibition with the effects of various 6-hydroxydopamine treatments on d-amphetamine induced motor activity

1974 • 135 citations

Diethyldithiocarbamate and amphetamine stereotype behaviour

1966 • 133 citations

Effects of 6-Hydroxydopamine on CNS Catecholamines, Spontaneous Motor Activity and Amphetamine Induced Hyperactivity in Rats

1970 • 131 citations

Gabaergic processes involved in the control of dopamine release from nigrostriatal dopaminergic neurons in the cat

1978 • 125 citations

Mechanism of action of cocaine and amphetamine in the brain

1962 • 124 citations

Dopaminergic neurons: Role of presynaptic receptors in the regulation of transmitter biosynthesis

1978 • 124 citations

EFFECTS OF D-AMPHETAMINE UPON BRAIN AMINE CONTENT AND LOCOMOTOR ACTIVITY OF MICE.

1965 • 123 citations

Specificity of dopaminergic neuronal degeneration induced by intracerebral injection of 6-hydroxydopamine in the nigrostriatal dopamine system

1976 • 122 citations

Mechanism of the γ-hydroxybutyrate-induced increase in brain dopamine and its relationship to “sleep”

1970 • 118 citations

Lesions in corpus striatum and cortex of rat brains and the effect on pharmacologically induced stereotyped, aggressive and cataleptic behaviour

1970 • 116 citations

Amphetamine Response in Rat after Dopamine Neurone Destruction

1972 • 116 citations

A comparison of the abilities of typical neuroleptic agents and of thioridazine, clozapine, sulpiride and metoclopramide to antagonise the hyperactivity induced by dopamine applied intracerebrally to areas of the extrapyramidal and mesolimbic system

1976 • 115 citations

Degeneration and Regrowth of Adrenergic Nerve Fibers in the Rat Peripheral Tissues after 6-Hydroxydopamine

1971 • 115 citations

Attenuation of amphetamine‐induced motor stimulation and stereotypy by 6‐hydroxydopamine in the rat

1973 • 114 citations

Behavioral pharmacology

1976 • 112 citations

Disappearance of the locus coeruleus in the rat after intraventricular 6-hydroxydopamine

1972 • 111 citations

Effect of apomorphine on motility in rats

1972 • 111 citations

The role of biogenic amines in the extra-pyramidal system.

1969 • 110 citations

Postsynaptic receptors are not essential for dopaminergic feedback regulation

1977 • 110 citations

SELECTIVE INCREASE OF BRAIN DOPAMINE INDUCED BY γ‐HYDROXYBUTYRATE: STUDY OF THE MECHANISM OF ACTION*

1968 • 107 citations

Circling behaviour produced by unilateral lesions in the region of the locus coeruleus in rats

1975 • 105 citations

Haloperidol increases and apomorphine decreases striatal dopamine metabolism after destruction of striatal dopamine-sensitive adenylate cyclase by kainic acid

1977 • 104 citations

Characterisation of the mechanisms by which purported dopamine agonists reduce spontaneous locomotor activity of mice

1981 • 100 citations

Antagonism of the hyperactivity induced by dopamine applied intracerebrally to the nucleus accumbens septi by typical neuroleptics and by clozapine, sulpiride and thioridazine

1976 • 100 citations

Effects of L-Dopa on Norepinephrine Metabolism in the Brain

1971 • 97 citations

The combined use of α-methyltyrosine and threo-dihydroxyphenylserine—selective reduction of dopamine levels in the central nervous system

1968 • 97 citations

Differential effects of Para-chlorophenylalanine on amphetamine-induced locomotion and stereotypy

1976 • 97 citations

Behavioral effects of dopamine and p-hydroxyamphetamine injected into corpus striatum of rats

1971 • 96 citations

Advances in Biochemical Pharmacology

1994 • 96 citations

Genetic variations in midbrain dopamine cell number: Parallel with differences in responses to dopaminergic agonists and in naturalistic behaviors mediated by central dopaminergic systems

1981 • 95 citations

Time course of the effects of 6‐hydroxydopamine on catecholamine‐containing neurones in rat hypothalamus and striatum

1970 • 94 citations

Studies on the action of some psychoactive drugs on central noradrenaline neurones after inhibition of dopamine-β-hydroxylase

1970 • 94 citations

The effect of inhibition of catecholamine synthesis on dexamphetamine induced central stimulation

1970 • 94 citations

Magnitude and duration of hyperactivity following neonatal 6-hydroxydopamine is related to the extent of brain dopamine depletion

1981 • 94 citations

DEGENERATION OF CENTRAL AND PERIPHERAL NORADRENALINE NEURONS PRODUCED BY 6‐HYDROXY‐DOPA

1972 • 93 citations

Injection of low doses of apomorphine into the nucleus accumbens of rats reduces locomotor activity

1981 • 90 citations

Studies on the behavioural effects of tryptophan and p-chlorophenylalanine

1976 • 90 citations

Design of agents for stimulation of neostriatal dopaminergic mechanisms

1974 • 90 citations

Different behavioural patterns induced by apomorphine: Evidence that the method of administration determines the behavioural response to the drug

1977 • 90 citations

Neuroleptic antagonism of the motor inhibitory effects of apomorphine within the nucleus accumbens: Drug interaction at presynaptic receptors?

1980 • 89 citations

Dopamine receptors explained

1982 • 88 citations

Collateral sprouting and reduced activity of the rat mesocortical dopaminergic neurons after selective destruction of the ascending noradrenergic bundles

1979 • 85 citations

Lesions in the nuclei accumbens septi of the rat: Behavioral and neurochemical effects.

1970 • 85 citations

Transport and Storage of Biogenic Amines

1972 • 81 citations

The contribution of tryptamine to the behavioural effects of l-tryptophan in tranylcypromine-treated rats

1978 • 80 citations

Stereotypic and anticataleptic activities of amphetamine after intracerebral injections

1972 • 76 citations

The Effect of Dopamine and Noradrenaline Antagonists on Amphetamine Induced Locomotor Activity in Mice and Rats

1973 • 75 citations

On the role of brain catecholamines in motor activity: Experiments with inhibitors of synthesis and of monoamine oxidase

1970 • 74 citations

Brain and heart catecholamine levels after l-Dopa administration in reserpine treated mice: Correlations with a conditioned avoidance response

1964 • 73 citations

The effect of isolation on catecholamine concentration and turnover in discrete areas of the rat brain

1977 • 73 citations

The effect of clonidine on locomotor activity in mice

1972 • 73 citations

Differential effects of serotonin on turning and stereotypy induced by apomorphine

1975 • 73 citations

Apomorphine and amphetamine stereotypy after 6-hydroxydopamine lesions of the substantia nigra

1974 • 73 citations

Modification of the behavioural changes induced by amphetamine in the rat by lesions in the caudate nucleus, the caudate-putamen and globus pallidus

1972 • 72 citations

High correlations between number of dopamine cells, dopamine levels and motor performance

1977 • 71 citations

Sensory neglect after lesions of substantia nigra or lateral hypothalamus: Differential severity and recovery of function

1979 • 70 citations

Effects of l-tryptophan on motor activity in mice

1973 • 70 citations

STUDIES ON THE BEHAVIOURAL PHARMACOLOGY OF A CYCLIC ANALOGUE OF DOPAMINE FOLLOWING ITS INJECTION INTO THE BRAINS OF CONSCIOUS RATS

1975 • 69 citations

Effects of disulfiram and diethyldithiocarbamate on spontaneous locomotor activity and brain catecholamine levels in mice

1969 • 68 citations

The roles of noradrenaline and dopamine in contraversive circling behaviour seen after unilateral electrolytic lesions of the locus coeruleus

1976 • 67 citations

Regulation of nigrostriatal and tuberoinfundibular-hypophyseal dopaminergic neurons

1979 • 67 citations

Neuroleptic antagonism of dyskinetic phenomena

1975 • 66 citations

Inhibition of norepinephrine biosynthesis at the dopamine-beta-hydroxylation stage.

1966 • 66 citations

Accumulation of dopamine in the parenchyma after decarboxylase inhibition in the capillaries of brain

1968 • 65 citations

DOPAMINE ACETYLCHOLINE IMBALANCE IN PARKINSON'S DISEASE

1976 • 64 citations

P-chloroamphetamine: in vivo investigations on the mechanism of action of the selective depletion of cerebral serotonin.

1970 • 63 citations

Effect of noradrenaline and 5-hydroxytryptamine depletion on locomotion in the cat

1980 • 63 citations

Effects of the unilateral nigral application of dopaminergic drugs on the in vivo release of dopamine in the two caudate nuclei of the cat

1979 • 60 citations

Tissue Concentrations of Digoxin in an Autopsy Material

1974 • 60 citations

Apomorphine and central serotonin neurons.

1973 • 60 citations

Correlation between behavioral and biochemical effects of p-chlorophenylalanine in mice and rats

1969 • 59 citations

Further studies on the antagonism of stereotyped behaviour induced by amphetamine

1969 • 58 citations

Physiological and behavioral effects of parachlorophenylalanine in the rat

1973 • 56 citations

Reversal of α-methyltyrosine-induced behavioural depression with dihydroxyphenylalanine and amphetamine

1967 • 55 citations

Dopamine receptor sensitivity following nigrostriatal lesion in the aged rat

1982 • 54 citations

Hyperactivity response to apomorphine and amphetamine in the mouse: the importance of the nucleus accumbens and caudate-putamen

1979 • 53 citations

Behavioral effects of amphetamine in rats with lesions in the corpus striatum.

1974 • 52 citations

Impairment of avoidance performance by intrastriatal administration of 6-hydroxydopamine

1974 • 51 citations

Kainic acid injections in the striatum alter the cataleptic and locomotor effects of drugs influencing dopaminerig and cholinergic systems

1981 • 50 citations

Enhancement of amphetamine action after interruption of ascending serotonergic pathways.

1974 • 50 citations

Decreased spiroperidol and LSD binding in rat brain after continuous amphetamine

1980 • 49 citations

Behavioral effects of unilateral dopamine injection into dorsal or ventral striatum

1981 • 49 citations

Acute effects of 6-hydroxydopa on central monoaminergic neurons

1973 • 48 citations

Simultaneous demonstration of the activation of presynaptic dopamine autoreceptors and postsynaptic dopamine receptors in vitro by N,N-dipropyl-5,6-ADTN

1980 • 48 citations

Changes in dopaminergic terminal excitability induced by amphetamine and haloperidol

1981 • 47 citations

Differential effects of certain dopaminergic drugs on the striatal concentration of dopamine metabolites, with special reference to 3-methoxytyramine

1981 • 47 citations

The effect of dl-propranolol, d-propranolol and practolol on the hyperactivity induced in rats by prolonged isolation

1973 • 47 citations

Long lasting stimulation of locomotor activity produced by the intraventricular injection of a cyclic analogue of dopamine into conscious mice

1974 • 46 citations

Effect of two dopamine receptor blockers on a serotonin-mediated behavioral syndrome in rats

1974 • 46 citations

The role of tryptamine in the behavioural effects of tranylcypromine + l-tryptophan

1979 • 46 citations

On the role of serotonin in apomorphine-induced locomotor stimulation in rats

1974 • 45 citations

The effect of l-dopa and (+)-amphetamine on the locomotor activity after pimozide and phenoxybenzamine

1972 • 45 citations

Dopamine, noradrenaline and 5-hydroxy-tryptamine in relation to motor activity, fighting and mounting behaviour

1973 • 44 citations

Central effects of scopolamine and (+)-amphetamine on locomotor activity: Interaction with strain and stress variables

1975 • 44 citations

BEHAVIOURAL CHANGES INDUCED IN CONSCIOUS MICE BY INTRACEREBROVENTRICULAR INJECTION OF CATECHOLAMINES, ACETYLCHOLINE AND 5‐HYDROXYTRYPTAMINE

1975 • 44 citations

Influence of midbrain raphe lesion on some pharmacological and biochemical effects of apomorphine in rats

1974 • 43 citations

The effect of L-DOPA on brain catecholamines and motility in rats

1971 • 43 citations

The relative importance of dopamine and noradrenaline receptor stimulation for the restoration of motor activity in reserpine or α-methyl-p-tyrosine pre-treated mice

1976 • 42 citations

Noradrenergic pathways and sleep-waking states in cats

1973 • 42 citations

Behavioural and biochemical changes following chronic administration of L-DOPA to rats

1982 • 42 citations

Eating, drinking and activity in rats following 5-hydroxytryptophan (5-HTP) administration

1964 • 42 citations

Specific antagonism by dopamine inhibitors of items of amphetamine induced aggressive behaviour

1972 • 42 citations

The recovery of noradrenaline in adrenergic nerve terminals of the rat after reserpine treatment

1971 • 40 citations

Role of amino acids and peptides in synaptic transmission

1973 • 40 citations

Detailed analysis of the effects of apomorphine and d-amphetamine on spontaneous locomotor behaviour of rats as measured in a TV-based, automated open-field system

1981 • 39 citations

Failure of dopamine to accumulate in central noradrenaline neurons after depletion with diethyldithiocarbamate

1967 • 39 citations

Effect of dopalanine on behaviour in mice depleted of norepinephrine or serotonin

1969 • 38 citations

The effect of manipulation of cholinergic mechanisms on turning behaviour in mice with unilateral destruction of the nigro-neostriatal dopaminergic system

1978 • 37 citations

Dopamine release and direct dopamine receptor activation in the central nervous system by D-145, an amantadine derivative

1973 • 37 citations

Regulatory deficits after unilateral electrolytic or 6-OHDA lesions of the substantia nigra

1973 • 35 citations

Muscimol a GABA-agonist injected into the nucleus accumbens increases apomorphine stereotypy and decreases the motility

1977 • 35 citations

THE PREVENTION BY INHIBITORS OF BRAIN PROTEIN SYNTHESIS OF THE HYPERACTIVITY AND HYPERPYREXIA PRODUCED IN RATS BY MONOAMINE OXIDASE INHIBITION AND THE ADMINISTRATION OF L‐TRYPTOPHAN OR 5‐METHOXY‐N,N‐DIMETHYLTRYPTAMINE

1972 • 35 citations

The effects of drugs on the behavioural and biochemical actions of intraventricular 6-hydroxydopamine

1972 • 34 citations

Effects of p-chloroamphetamine on locomotor activity and brain 5-hydroxyindoles

1976 • 34 citations

HYPERACTIVE STATES RELATED TO THE METABOLISM OF NOREPINEPHRINE AND SIMILAR BIOCHEMICALS

1969 • 34 citations

Inhibition and potentiation of apomorphine-induced hypermotility in rats by neuroleptics

1976 • 33 citations

Characterisation of the mechanisms for hyperactivity induction from the nucleus accumbens by phenylethylamine derivatives

1976 • 33 citations

Functional aspects of 5-hydroxytryptamine turnover in the central nervous system.

1974 • 33 citations

Comparison between behaviours elicited by high doses of amphetamine and fenfluramine: Implications for the concept of stereotypy

1974 • 33 citations

Release of dopamine from central noradrenaline and dopamine nerves induced by a dopamine-?-hydroxylase inhibitor

1973 • 33 citations

Dopamine and Its Physiological Significance in Brain Function

1972 • 33 citations

Effect of 1,4-butanediol and other butyric acid congeners on brain catecholamines

1968 • 32 citations

Blockade by pimozide of (+)-amphetamine-induced hyperkinesia in mice

1972 • 30 citations

Circadian rhythm in blood and brain biogenic amines and other biochemical changes in rabbits

1974 • 30 citations

Aporphines 16 Action of aporphine alkaloids on locomotor activity in rats with 6-hydroxydopamine lesions of the nucleus accumbens

1976 • 30 citations

De la potentialisation des effets de la DOPA par les inhibiteurs de la monoamineoxydase

1966 • 30 citations

Differential effects of dopamine agonists in mature and immature rats

1981 • 29 citations

Nucleus accumbens lesions reduce amphetamine hyperthermia but not hyperactivity

1978 • 29 citations

Studies on the locomotor activity produced by injection of dibutyryl cyclic 3 5 AMP into the nucleus accumbens of rats

1978 • 28 citations

<scp>l</scp>‐3, 4‐Dihydroxyphenylalanine and <scp>l</scp>‐5‐Hydroxytryptophan Decarboxylase Activities in Rat Striatum: Effect of Selective Destruction of Dopaminergic or Serotoninergic Input

1980 • 27 citations

Restoration of locomotor activity in mice by lowl-DOPA doses after suppression by α-methyltyrosine but not by reserpine

1973 • 27 citations

Functional effects of local injections of dopamine and analogs into the neostriatum and nucleus accumbens.

1977 • 26 citations

Modification by propranolol and related compounds of motor activity and stereotype behaviour induced in the rat by amphetamine

1974 • 26 citations

Changed eating and locomotor behaviour in the rat after 6-hydroxydopamine lesions to the substantia nigra

1975 • 26 citations

Circadian variations of noradrenaline, 5-hydroxytryptamine and dopamine in specific brain areas of C57B1/6 and BALB/c mice

1982 • 24 citations

Stress-related effects of various inhibitors of catecholamine synthesis in the mouse.

1971 • 24 citations

A new centrally acting DA-receptor agonist with selectivity for autoreceptors.

1980 • 24 citations

On the mechanism of central action of amphetamine: The role of catecholamines

1973 • 23 citations

Effect of intraventricular amines on motor activity in hypothermic rats.

1974 • 23 citations

Differential behavioral changes following intrastriatal application of 6-hydroxydopamine

1977 • 23 citations

Enhancement of drug-induced motor activity by an inhibitor of phenylethanolamine-N-methyltransferase

1978 • 23 citations

Modification by two beta‐adrenergic blocking drugs of the effects of methamphetamine on behaviour and brain metabolism of mice¹

1971 • 23 citations

Neuroleptic interaction with the serotoninergic-dopaminergic mechanisms in the nucleus accumbens

1978 • 23 citations

Functional antagonism between dopamine and noradrenaline within the caudate nucleus of cats: A phenomenon of rhythmically changing susceptibility

1978 • 22 citations

Catecholamines in Regulation of Motor Function

1975 • 22 citations

Amphetamine isomers: Influences on locomotor and stereotyped behavior of cats

1974 • 22 citations

Effects of dopamine receptor stimulants on locomotor activity of rats with electrolytic or 6-hydroxydopamine-induced lesions of the nucleus accumbens

1976 • 22 citations

Circling behavior in rodents following an imbalance of basal ganglia GABA concentrations

1977 • 21 citations

Central effects of 6-hydroxydopamine

1971 • 20 citations

THE EFFECT OF APOMORPHINE AND CLONIDINE ON LOCOMOTOR ACTIVITY IN MICE AFTER LONG TERM TREATMENT WITH HALOPERIDOL

1977 • 20 citations

Inhibitory effects of propranolol and oxprenolol on excitation induced by a MAO inhibitor and reserpine in the mouse

1976 • 19 citations

Influence of pimozide on the locomotor hyperactivity produced by caffeine

1979 • 19 citations

The puzzling ‘cascade’ of multiple receptors for dopamine

1981 • 18 citations

d-Amphetamine at low doses suppresses noradrenergic functions

1981 • 18 citations

6-Ohda lesion to the dorsal noradrenergic bundle alters morphine-induced locomotor activity and catalepsy

1978 • 18 citations

Dissociation by the aporphine derivatives of the stereotypic and hyperactivity responses resulting from injections into the nucleus accumbens septi

1975 • 18 citations

Effects of amantadine, amphetamine and apomorphine on the locomotor activity in rats

1973 • 17 citations

Piperidine: Effects on locomotor activity and brain monoamine turnover

1976 • 17 citations

Chronic L-DOPA treatment of mice: A behavioural and biochemical study

1981 • 16 citations

A comparison of the locomotor effects of 5-hydroxytryptamine and 5-hydroxytryptophan administered via two systemic routes

1974 • 15 citations

Effect of para-methoxyamphetamine on catecholamine metabolism in the mouse brain

1971 • 15 citations

The effect of diethyldithiocarbamate on amphetamine-induced behaviour in rats

1971 • 15 citations

Shifting of the d-amphetamine dose-response curve in rats with frontal cortical ablations

1974 • 14 citations

The role of the substantia nigra in the locomotor stimulant action of amphetamine

1973 • 14 citations

Some central effects of diethyldithiocarbamate administered intraventricularly in rats

1970 • 14 citations

Comparison of the locomotor stimulant mechanisms of action of d-amphetamine and d-amphetamine plus l-dopa: possible involvement of serotonin.

1974 • 13 citations

Influence of catecholamines on dexamphetamine-induced changes in locomotor activity

1978 • 13 citations

Induction of swimming in the high spinal stingray by L-DOPA

1981 • 13 citations

Comparative effects of dl-p-methoxyamphetamine and d-amphetamine on catecholamine release and reuptake in vitro.

1974 • 13 citations

Behavioural supersensitivity to apomorphine following cerebral dopaminergic denervation by 6-hydroxydopamine

1975 • 13 citations

The effects of lesions in the head of the caudate nucleus on spontaneous and L-DOPA induced activity in the cat

1973 • 13 citations

Differential Effects of Reserpine on Conditioned Responses in Cats

1958 • 12 citations

Potentiation of amphetamine-induced hyperactivity by acute but not by chronic para-chlorophenylalanine treatment in the rat

1976 • 12 citations

The spontaneous motility of rats after intraventricular injection of dopamine

1972 • 11 citations

Long-term haloperidol-treatment of mice: A change in ?-adrenergic receptor responsiveness

1979 • 10 citations

A comparative study of d- and l-amphetamine on the open field performance of rats

1974 • 9 citations

The role of dopamine as a neurotransmittor in the central and the autonomic nervous system.

1978 • 9 citations

Qualitative aspects on motility changes in mice induced by low doses of apomorphine and clonidine

1979 • 9 citations

Inhibition of Apomorphine‐induced Hypermotility in Rats by Chlorpromazinc, Perphenazine, Thioridazine and Melperone

1977 • 8 citations

The ineffectiveness of desipramine pretreatment on behavioral effects of 6-hydroxydopamine in nialamide-pretreated rats

1974 • 8 citations

Intraventricular injections of L-Dopa: The effect on rat locomotor activity and body temperature

1973 • 7 citations

Pharmacological and biochemical aspects of hyperkinetic disorders

1979 • 7 citations

Inhibition of Apomorphine-induced Hypermotility in Rats by Chlorpromazinc, Perphenazine, Thioridazine and Melperone

1977 • 7 citations

Effect of dopamine-β-hydroxylase inhibitors 1,1-dimethyl-3-phenyl-2-thiourea, fusaric acid and dimethyldithiocarbamate, on the rat brain monoamine content following intraventricular injection of l-dopa

1973 • 7 citations

The effect of p-Chlorophenylalanine on the pethidine- or methadone-induced decrease in locomotor activity of rats

1976 • 7 citations

Effects of harmine and brain lesions on apomorphine induced motor activity

1976 • 5 citations

Studies on the mechanism of the akinetic effects of gamma-hydroxybutyric acid and 1, 4-butanediol.

1973 • 5 citations

The short- and long-term effects of haloperidol on rat central dopamine turnover

1982 • 4 citations

The central action of beta-adrenergic receptor blocking agents. I. The central action of intraventricularly administered isoprenaline in the rat.

1974 • 3 citations

Behavioral Effects of Amphetamine in Brain Damaged Animals: Problems in the Search for Sites of Action

1977 • 3 citations

Recent Advances in the Treatment of Hypertension

1977 • 3 citations

Influence of noradrenaline, 5-hydroxytryptamine and acetylcholine injected intraventricularly on the rat's behaviour.

1973 • 2 citations

Effect of 6-hydroxydopamine pretreatment upon L-dopa-induced scatter jumping in mice.

1973 • 2 citations

Recent advances in the treatment of hypertension

1977 • 2 citations

Influence of propranolol on some behavioural effects of amphetamine in the cat

1972 • 1 citations