ehavioural evidence for supersensitivtiy of postsynaptic dopamine receptors in the mesolimbic system after chronic administration of desipramine

Amphetamine and apomorphine responses in the rat following 6-OHDA lesions of the nucleus accumbens septi and corpus striatum

1975 • 1,741 citations

Adipsia and Aphagia after 6‐Hydroxydopamine Induced Degeneration of the Nigro‐striatal Dopamine System

1971 • 1,271 citations

Antischizophrenic Drugs: Chronic Treatment Elevates Dopamine Receptor Binding in Brain

1977 • 1,017 citations

Catecholamine theories of reward: A critical review

1978 • 766 citations

Development of β-adrenergic receptor subsensitivity by antidepressants

1977 • 727 citations

INTENSIFICATION OF THE CENTRAL SEROTONINERGIC PROCESSES AS A POSSIBLE DETERMINANT OF THE THYMOLEPTIC EFFECT

1969 • 705 citations

Effect of antidepressant drugs on the depletion of intraneuronal brain 5-hydroxytryptamine stores caused by 4-methyl-α-ethyl-meta-tyramine

1969 • 645 citations

The pharmacological and anatomical substrates of the amphetamine response in the rat

1975 • 583 citations

A selective inhibitor of serotonin uptake: Lilly 110140, 3-(p-Trifluoromethylphenoxy)-n-methyl-3-phenylpropylamine

1974 • 461 citations

Presynaptic modulation of beta adrenergic receptors in rat cerebral cortex after treatment with antidepressants.

1978 • 440 citations

Antidepressants and the Muscarinic Acetylcholine Receptor

1977 • 429 citations

A possible common mechanism of action of antidepressant treatments

1976 • 410 citations

Feedback Inhibition of Brain Noradrenaline Neurons by Tricyclic Antidepressants: α-Receptor Mediation

1978 • 396 citations

Effect of Psychotropic Drugs on the Uptake of H ³ -Norepinephrine by Tissues

1961 • 365 citations

Presynaptic Alpha-Receptor Subsensitivity After Long-Term Antidepressant Treatment

1978 • 320 citations

Catecholamine receptor agonists

1976 • 318 citations

Regional studies of catecholamines in the rat brain. IV. Effects of drugs on the disposition and metabolism of H3-norepinephrine and H3-dopamine.

1966 • 307 citations

Drugs and Reinforcement Mechanisms: A Critical Review of the Catecholamine Theory

1978 • 293 citations

Catecholamine uptake by synaptosomes from rat brain. Structure-activity relationships of drugs with differential effects on dopamine and norepinephrine neurons.

1971 • 283 citations

Ascending catecholamine pathways and amphetamine-induced locomotor activity: Importance of dopamine and apparent non-involvement of norepinephrine

1975 • 259 citations

On the Slowness of Action of Tricyclic Antidepressant Drugs

1972 • 226 citations

Differential effects of antidepressant treatment on brain monoaminergic receptors

1980 • 222 citations

Repeated tricyclics induce a progressive dopamine autoreceptor subsensitivity independent of daily drug treatment

1980 • 208 citations

Chronic treatment with antidepressants prevents the inhibitory effect of small doses of apomorphine on dopamine synthesis and motor activity

1979 • 193 citations

Neuropsychopharmacology and the Affective Disorders

1969 • 168 citations

Functional evidence for subsensitivity of noradrenergic α2 receptors after chronic desipramine treatment

1980 • 150 citations

Functional Aspects of the Norepinephrine Receptor Coupled Adenylate Cyclase System in the Limbic Forebrain and its Modification by Drugs which Precipitate or Alleviate Depression: Molecular Approaches to an Understanding of Affective Disorders

1978 • 132 citations

Psychoactive drug effects on a system which generates cyclic AMP in brain

1976 • 124 citations

Modifications of central 5-hydroxytryptamine binding sites in synaptic membranes from rat brain after long-term administration of tricyclic antidepressants

1979 • 119 citations

The pharmacology of iprindole, a new antidepressant

1969 • 111 citations

The conversion in vivo of d-amphetamine to (+)-p-hydroxynorephedrine

1965 • 102 citations

On the mechanism of amphetamine potentiation by desipramine (DMI)

1966 • 97 citations

Amitriptyline: Long-term treatment elevates α-adrenergic and muscarinic receptor binding in mouse brain

1980 • 93 citations

Neuropsychopharmacology and the Affective Disorders

1969 • 92 citations

Influence of acute and chronic treatment with desmethylimipramine on catecholamine effects in the rat.

1978 • 76 citations

Apomorphine and amphetamine stereotypy after 6-hydroxydopamine lesions of the substantia nigra

1974 • 73 citations

The effect of repeated administration of antidepressant drugs on the responsiveness of rats to catecholamine agonists

1979 • 66 citations

Cholinergic and anticholinergic influences on amphetamine-induced stereotyped behavior

1972 • 62 citations

Influence of various psychoactive drugs on the in vivo metabolism of d-Amphetamine in the rat

1969 • 58 citations

Neuroamine-derived alkaloids: Substrate-preferred inhibitors of rat brain monoamine oxidase in vitro

1976 • 46 citations

The Pulmonary Vasoconstrictor Response to Hypoxia: Effects of Inhibitors of Prostaglandin Biosynthesis

1975 • 43 citations

Norepinephrine-stimulated cyclic AMP accumulation in brain slices in vitro after serotonin depletion or chronic administration of selective amine reuptake inhibitors.

1977 • 40 citations

Interaction of imipramine and desmethylimipramine with tremorine and oxotremorine in mice

1967 • 20 citations

Antagonism of lobeline by ganglion-blocking agents at afferent nerve endings.

1966 • 5 citations