DOPAMINE ACETYLCHOLINE IMBALANCE IN PARKINSON'S DISEASE

Postsynaptic Supersensitivity after 6‐Hydroxy‐dopamine Induced Degeneration of the Nigro‐striatal Dopamine System

1971 • 1,922 citations

The neurosciences. Third study program

1975 • 1,465 citations

Behavioural supersensitivity to apomorphine following chronic treatment with drugs which interfere with the synaptic function of catecholamines

1974 • 451 citations

Induced acetylcholinesterase-rich layer in rat dentate gyrus following entorhinal lesions

1972 • 451 citations

CHOLINE: SELECTIVE ACCUMULATION BY CENTRAL CHOLINERGIC NEURONS

1973 • 435 citations

Cholinergic-Anticholinergic Antagonism in Parkinsonism

1967 • 337 citations

The pathogenesis of Parkinson's disease: a new hypothesis.

1962 • 337 citations

Plastic changes in the adrenergic innervation of the rat septal area in response to denervation

1971 • 320 citations

SPROUTING AS A CAUSE OF SPASTICITY

1958 • 302 citations

Neostriatal choline acetylase and cholinesterase following selective brain lesions

1971 • 279 citations

Influences of cholinergic mechanisms on the function and turnover of brain dopamine

1971 • 266 citations

Enhanced striatal acetylcholine release by chlorpromazine and its reversal by apomorphine

1973 • 263 citations

Enhancement of Dopamine-Stimulated Adenylate Cyclase Activity in Rat Caudate after Lesions in Substantia Nigra: Evidence for Denervation Supersensitivity

1974 • 228 citations

Turning behavior of mice with unilateral 6-hydroxydopamine lesions in the striatum: Effects of apomorphine, l-DOPA, amantadine, amphetamine and other psychomotor stimulants

1973 • 204 citations

Drug-Induced Extrapyramidal Reactions

1961 • 199 citations

Origin and modulation of acetylcholine activity in the neostriatum

1974 • 174 citations

Electrophysiological evidence for involvement of cyclic adenosine monophosphate in dopamine responses of caudate neurons

1974 • 162 citations

Influence of noncholinergic drugs on rat striatal acetylcholine levels

1974 • 160 citations

In vivo identification of muscarinic cholinergic receptor binding in rat brain

1974 • 160 citations

Temporal changes in amine synthesizing enzymes of rat extrapyramidal structures after hemitransections or 6-hydroxydopamine administration

1973 • 157 citations

In vivo inhibition of striatal acetylcholine turnover by L-DOPA, apomorphine and (+)-amphetamine

1975 • 145 citations

Pharmacologically Induced Behavioural Supersensitivity to Apomorphine

1973 • 136 citations

L-glutamate decarboxylase and Choline acetyltransferase activity in the substantia nigra and the striatum after surgical interruption of the strio-nigral fibres of the baboon

1974 • 130 citations

Injected Apomorphine and Orally Administered Levodopa in Parkinsonism

1972 • 130 citations

Choline acetyltransferase and acetylcholinesterase in fascia dentata following lesion of the entorhinal afferents

1974 • 129 citations

The demonstration of acetylcholinesterase containing neurones within the caudate nucleus of the rat

1972 • 124 citations

Enhanced sensitivity of caudate neurones to microiotophoretic injections of dopamine in 6-hydroxydopamine treated cats

1972 • 121 citations

Cholinergic-dopaminergic interaction in the striatum: The effect of 6-hydroxydopamine or pimozide treatment on the increased striatal acetylcholine levels induced by apomorphine, piribedil andD-amphetamine

1975 • 98 citations

Choline uptake by nerve terminals: A sensitive and a specific marker of cholinergic innervation

1974 • 95 citations

Dopaminergic denervation supersensitivity and dopamine stimulated adenyl cyclase activity

1973 • 84 citations

Oxotremorine and central monoamine neurons

1967 • 83 citations

Altered response to apomorphine in 6-hydroxydopamine-treated rats

1972 • 82 citations

Supersensitivity of caudate neurones after repeated administration of haloperidol

1975 • 75 citations

Cholinergic Enzyme Systems in Parkinson's Disease

1971 • 67 citations

Enhancement of apomorphine-induced inhibition of striatal dopamine-turnover following chronic haloperidol

1975 • 63 citations

Effect of oxotremorine on homovanillic acid concentration in the striatum of the rat

1974 • 62 citations

Atropine-induced changes of cerebral dopamine turnover

1971 • 57 citations

Neurochemical evidence for denervation supersensitivity: The effect of unilateral substantia nigra lesions on apomorphine-induced increases in neostriatal acetylcholine levels

1974 • 55 citations

Effect of chronic amphetamine exposure on stereotyped behavior: implications for pathogenesis of l-dopa-induced dyskinesias.

1975 • 51 citations

Striatal adenylate cyclase activity following reserpine and chronic chlorpromazine administration in rats

1975 • 39 citations

THE EFFECTS OF ACETYLCHOLINE AND DOPAMINE ON THE CAUDATE NUCLEUS DEPLETED OF BIOGENIC AMINES

1975 • 39 citations

Anatomical and Physiological Correlates of Plasticity in the Central Nervous System

1973 • 33 citations

Chemistry of dopamine receptors.

1975 • 29 citations

BRAIN ACETYLCHOLINESTERASE IN PARKINSON'S DISEASE

2009 • 28 citations

Hyperpolarizing synaptic inhibition in cat neocortex

1973 • 10 citations

Neuronal hyposensitivity to dopamine in the caudate nucleus depleted of biogenic amines by tegmental lesions

1974 • 10 citations