RhoA is required for cortical retraction and rigidity during mitotic cell rounding

Rho GTPases and the Actin Cytoskeleton

1998 • 6,129 citations

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

1992 • 4,454 citations

Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension

1997 • 2,847 citations

Regulation of Myosin Phosphatase by Rho and Rho-Associated Kinase (Rho-Kinase)

1996 • 2,843 citations

Rho GTPases and signaling networks

1997 • 2,380 citations

Phosphorylation and Activation of Myosin by Rho-associated Kinase (Rho-kinase)

1996 • 1,964 citations

Rho GTPases and their effector proteins

2000 • 1,941 citations

Rho-stimulated contractility drives the formation of stress fibers and focal adhesions.

1996 • 1,614 citations

Signaling from Rho to the Actin Cytoskeleton Through Protein Kinases ROCK and LIM-kinase

1999 • 1,581 citations

Regulation of the small GTP-binding protein Rho by cell adhesion and the cytoskeleton

1999 • 1,558 citations

Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations.

1993 • 1,086 citations

Cooperation between mDia1 and ROCK in Rho-induced actin reorganization

1999 • 884 citations

The small GTP-binding protein Rho binds to and activates a 160 kDa Ser/Thr protein kinase homologous to myotonic dystrophy kinase.

1996 • 872 citations

p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin

1997 • 819 citations

Microinjection of recombinant p21rho induces rapid changes in cell morphology.

1990 • 720 citations

A Novel Serine/Threonine Kinase Binding the Ras-related RhoA GTPase Which Translocates the Kinase to Peripheral Membranes

1995 • 711 citations

Nucleotide exchange factor GEF-H1 mediates cross-talk between microtubules and the actin cytoskeleton

2002 • 633 citations

The mammalian G protein rhoC is ADP-ribosylated by Clostridium botulinum exoenzyme C3 and affects actin microfilaments in Vero cells.

1989 • 529 citations

Anaphase onset in vertebrate somatic cells is controlled by a checkpoint that monitors sister kinetochore attachment to the spindle.

1994 • 511 citations

RhoA is required for monocyte tail retraction during transendothelial migration

2001 • 498 citations

RhoA Inactivation by p190RhoGAP Regulates Cell Spreading and Migration by Promoting Membrane Protrusion and Polarity

2001 • 431 citations

Integrin engagement suppresses RhoA activity via a c-Src-dependent mechanism

2000 • 429 citations

Cofilin Phosphorylation and Actin Cytoskeletal Dynamics Regulated by Rho- and Cdc42-Activated Lim-Kinase 2

1999 • 384 citations

Regulation of cytoplasmic division of Xenopus embryo by rho p21 and its inhibitory GDP/GTP exchange protein (rho GDI).

1993 • 363 citations

A cytoplasmic clock with the same period as the division cycle in Xenopus eggs.

1980 • 358 citations

Animal Cell Cytokinesis

2001 • 337 citations

Traction forces of cytokinesis measured with optically modified elastic substrata

1997 • 330 citations

Direct, high-resolution measurement of furrow stiffening during division of adherent cells

2001 • 321 citations

Phosphorylation of Adducin by Rho-Kinase Plays a Crucial Role in Cell Motility

1999 • 300 citations

Functional modification of a 21-kilodalton G protein when ADP-ribosylated by exoenzyme C3 of Clostridium botulinum.

1988 • 299 citations

Protein kinase C modulates in vitro phosphorylation of the smooth muscle heavy meromyosin by myosin light chain kinase.

1984 • 249 citations

Altered phosphorylation and activation of PP60c-src during fibroblast mitosis

1988 • 249 citations

Rho-kinase/ROCK is involved in cytokinesis through the phosphorylation of myosin light chain and not ezrin/radixin/moesin proteins at the cleavage furrow

2000 • 236 citations

Microtubule Disruption Induces the Formation of Actin Stress Fibers and Focal Adhesions in Cultured Cells: Possible Involvement of the Rho Signal Cascade.

1996 • 214 citations

Regulation of the Association of Adducin with Actin Filaments by Rho-associated Kinase (Rho-kinase) and Myosin Phosphatase

1998 • 209 citations

Phosphorylation of myosin-II regulatory light chain by cyclin-p34cdc2: a mechanism for the timing of cytokinesis.

1992 • 197 citations

Lysophosphatidic acid and microtubule-destabilizing agents stimulate fibronectin matrix assembly through Rho-dependent actin stress fiber formation and cell contraction.

1997 • 197 citations

Microtubule Depolymerization Induces Stress Fibers, Focal Adhesions, and DNA Synthesis via the GTP-Binding Protein Rho

1998 • 197 citations

Phosphorylation of non-muscle caldesmon by p34cdc2 kinase during mitosis

1991 • 171 citations

Accumulation of GTP-bound RhoA during Cytokinesis and a Critical Role of ECT2 in This Accumulation

2000 • 163 citations

In vivo phosphorylation of regulatory light chain of myosin II during mitosis of cultured cells

1994 • 154 citations

Location of cellular adhesions to solid substrata

1973 • 152 citations

Roles of Rho-associated Kinase and Myosin Light Chain Kinase in Morphological and Migratory Defects of Focal Adhesion Kinase-null Cells

2002 • 151 citations

Regulation of p190 Rho-GAP by v-Src is linked to cytoskeletal disruption during transformation

1999 • 148 citations

Actin polymerization induces a shape change in actin-containing vesicles.

1989 • 127 citations

Alteration of the cytoskeleton of mammalian cells cultured in vitro by Clostridium botulinum C2 toxin and C3 ADP-ribosyltransferase.

1991 • 126 citations

The Small GTP-binding Protein Rho Regulates Cortical Activities in Cultured Cells during Division

1999 • 125 citations

Investigation of the mechanism of retraction of the cell margin and rearward flow of nodules during mitotic cell rounding.

1997 • 122 citations

Dissociation of FAK/p130CAS/c-Src Complex during Mitosis: Role of Mitosis-specific Serine Phosphorylation of FAK

1999 • 121 citations

The Mechanical Properties of the Cell Surface

1955 • 111 citations

Analysis of cell division using fluorescently labeled actin and myosin in living PtK2 cells

1989 • 107 citations

Mitosis-specific Activation of LIM Motif-containing Protein Kinase and Roles of Cofilin Phosphorylation and Dephosphorylation in Mitosis

2002 • 105 citations

Regulation of cytoplasmic division of Xenopus embryo by rho p21 and its inhibitory GDP/GTP exchange protein (rho GDI)

1994 • 100 citations

Tension at the Surface of the Dividing Sea-Urchin Egg

1972 • 99 citations

Inhibition of RhoGAP activity is sufficient for the induction of Rho-mediated actin reorganization

1999 • 73 citations

Functional Modification of a 21-Kilodalton G Protein when ADP-Ribosylated by Exoenzyme C3 of Clostridium botulinum

1988 • 66 citations

Parameters That Specify the Timing of Cytokinesis

1999 • 66 citations

Advances in Cytokinesis Research. Role of Myosin Light Chain Phosphorylation in the Regulation of Cytokinesis.

2001 • 60 citations

Src tyrosine kinase activity down-regulates Rho-dependent responses during Shigella entry into epithelial cells and stress fibre formation

2000 • 59 citations

Stress fiber and cleavage furrow formation in living cells microinjected with fluorescently labeled α‐actinin

1987 • 56 citations

Mitosis specific serine phosphorylation and downregulation of one of the focal adhesion protein, paxillin

1997 • 56 citations

Cell surface changes during mitosis and cytokinesis of epithelial cells

1984 • 36 citations

Effects of taxol on microtubule organization in mouse splenic lymphocytes and on response to mitogenic stimulation.

1985 • 29 citations

Talin dynamics in living microinjected nonmuscle cells

1989 • 26 citations

Tyrosine 807 of the v-Fms oncogene product controls cell morphology and association with p120RasGAP

1995 • 22 citations

Protein kinase C mediates phosphorylation of the regulatory light chain of myosin-II during mitosis.

2001 • 17 citations

Deleted Work

1955 • 0 citations