Neuritic pathology and dementia in alzheimer's disease

Diagnosis of Alzheimer's Disease

1985 • 2,482 citations

Synapse loss in frontal cortex biopsies in Alzheimer's disease: Correlation with cognitive severity

1990 • 2,131 citations

Observations on the brains of demented old people

1970 • 2,066 citations

Neurotrophic and Neurotoxic Effects of Amyloid β Protein: Reversal by Tachykinin Neuropeptides

1990 • 1,975 citations

Microtubule-associated protein tau (tau) is a major antigenic component of paired helical filaments in Alzheimer disease.

1986 • 1,387 citations

Clinical, pathological, and neurochemical changes in dementia: A subgroup with preserved mental status and numerous neocortical plaques

1988 • 1,186 citations

Some morphometric aspects of the brain in senile dementia of the alzheimer type

1981 • 803 citations

Observations on the brains of non-demented old people

1968 • 656 citations

Plaques, tangles and dementia

1982 • 603 citations

A quantitative morphometric analysis of the neuronal and synaptic content of the frontal and temporal cortex in patients with Alzheimer's disease

1987 • 602 citations

Clinico‐pathologic studies in dementia

1988 • 567 citations

Formic acid pretreatment enhances immunostaining of cerebral and systemic amyloids.

1987 • 469 citations

The pattern of acquisition of plaques and tangles in the brains of patients under 50 years of age with Down's syndrome

1989 • 463 citations

Isolation of Low‐Molecular‐Weight Proteins from Amyloid Plaque Fibers in Alzheimer's Disease

1986 • 443 citations

Occurrence of neuropil threads in the senile human brain and in Alzheimer's disease: A third location of paired helical filaments outside of neurofibrillary tangles and neuritic plaques

1986 • 419 citations

Synaptic loss in Alzheimer's disease and other dementias

1989 • 406 citations

Alzheimer's disease. A double-labeling immunohistochemical study of senile plaques.

1988 • 381 citations

A4 amyloid protein deposition and the diagnosis of Alzheimer's disease

1988 • 367 citations

Immunohistochemical quantification of the synapse-related protein synaptophysin in Alzheimer disease

1989 • 353 citations

Axonal disruption and aberrant localization of tau protein characterize the neuropil pathology of Alzheimer's disease

1987 • 348 citations

Correlation between Scores for Dementia and Counts of ‘Senile Plaques’ in Cerebral Grey Matter of Elderly Subjects

1966 • 293 citations

Senile Dementia of the Alzheimer Type Without Neocortical Neurofibrillary Tangles

1987 • 269 citations

Alzheimer's disease: a correlative study.

1986 • 269 citations

Beta-protein amyloid is widely distributed in the central nervous system of patients with Alzheimer's disease.

1989 • 241 citations

Spectrum of morphological appearance of amyloid deposits in Alzheimer's disease

1989 • 219 citations

Alzheimer's disease and other dementing illnesses in a defined united states population: Incidence rates and clinical features

1987 • 204 citations

Choline acetyltransferase activity and histopathology of frontal neocortex from biopsies of demented patients

1982 • 200 citations

Alzheimer's disease: striatal amyloid deposits and neurofibrillary changes.

1990 • 192 citations

Quantitative histological studies on the aged human brain

1970 • 178 citations

Alzheimerʼs Disease

1990 • 171 citations

Ubiquitin immunoreactive structures in normal human brains. Distribution and developmental aspects.

1990 • 170 citations

Microtubular reorganization and dendritic growth response in alzheimer's disease

1989 • 159 citations

Defined neurofilament, tau, and beta-amyloid precursor protein epitopes distinguish Alzheimer from non-Alzheimer senile plaques.

1990 • 154 citations

Neuropil Threads Occur in Dendrites of Tangle—Bearing Nerve Cells

1988 • 147 citations

Morphology and distribution of plaque and related deposits in the brains of Alzheimer's disease and control cases. An immunohistochemical study using amyloid beta-protein antibody.

1989 • 143 citations

Alzheimer's disease: areal and laminar pathology in the occipital isocortex

1989 • 141 citations

Comparison of four staining methods on the detection of neuritic plaques

1989 • 120 citations

Quantitative histological studies on the aged human brain

1970 • 106 citations

About the presence of paired helical filaments in dystrophic neurites participating in the plaque formation

1989 • 105 citations

Distinctive, rapid, and easy labeling of diffuse plaques in the Alzheimer brains by a new methenamine silver stain

1990 • 89 citations

COMPARISON OF SEVEN STAINING METHODS FOR SENILE PLAQUES AND NEUROFIBRILLARY TANGLES IN A PROSPECTIVE SERIES OF 15 ELDERLY PATIENTS

1989 • 81 citations

Senile plaque neurites fail to demonstrate anti-paired helical filament and anti-microtubule-associated protein-tau immunoreactive proteins in the absence of neurofibrillary tangles in the neocortex

1989 • 65 citations

Comparison of three silver stains for demonstrating neurofibrillary tangles and neuritic plaques in brain tissue stored for long periods

1990 • 24 citations

Measurement of Water Potential of Leaves by Methods involving Immersion in Sucrose Solutions

1965 • 16 citations