Decrease of CD4+FOXP3+ T regulatory cells in the peripheral blood of human subjects undergoing a mental stressor

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2003 • 7,902 citations

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

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Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells

2010 • 5,969 citations

Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

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Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases.

1995 • 5,124 citations

Regulatory T Cells and Immune Tolerance

2008 • 4,778 citations

The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

2001 • 3,260 citations

Psychological Stress and the Human Immune System: A Meta-Analytic Study of 30 Years of Inquiry.

2004 • 3,037 citations

Central Memory and Effector Memory T Cell Subsets: Function, Generation, and Maintenance

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Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

1995 • 2,842 citations

Regulatory T cells, tumour immunity and immunotherapy

2006 • 2,009 citations

Loss of Functional Suppression by CD4+CD25+ Regulatory T Cells in Patients with Multiple Sclerosis

2004 • 1,835 citations

Stimulation of CD25+CD4+ regulatory T cells through GITR breaks immunological self-tolerance

2002 • 1,745 citations

Foxp3⁺CD25⁺CD4⁺ natural regulatory T cells in dominant self‐tolerance and autoimmune disease

2006 • 1,535 citations

Induction of Tumor Immunity by Removing CD25+CD4+ T Cells: A Common Basis Between Tumor Immunity and Autoimmunity

1999 • 1,475 citations

CD4+CD25+ Immunoregulatory T Cells

2002 • 1,434 citations

Role of LAG-3 in Regulatory T Cells

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Regulatory CD4(+)CD25(+) T cells in tumors from patients with early-stage non-small cell lung cancer and late-stage ovarian cancer.

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Natural regulatory T cells in infectious disease

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Mechanisms of suppression by suppressor T cells

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Acute Stress Enhances while Chronic Stress Suppresses Cell-Mediated Immunityin Vivo:A Potential Role for Leukocyte Trafficking

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Defective Suppressor Function in CD4+CD25+ T-Cells From Patients With Type 1 Diabetes

2005 • 825 citations

Regulatory T cells in cancer

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TGF-β1 Plays an Important Role in the Mechanism of CD4+CD25+ Regulatory T Cell Activity in Both Humans and Mice

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Tregs and rethinking cancer immunotherapy

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Catecholamine-Induced Leukocytosis: Early Observations, Current Research, and Future Directions

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In Vivo Activation of Antigen-Specific CD4 T Cells

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The role of acute and chronic stress in asthma attacks in children

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Association between stressful life events and exacerbation in multiple sclerosis: a meta-analysis

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Interleukin-2 gene variation impairs regulatory T cell function and causes autoimmunity

2007 • 367 citations

Defective Suppressor Function of Human CD4+ CD25+ Regulatory T Cells in Autoimmune Polyglandular Syndrome Type II

2004 • 359 citations

CD4 Effector T Cell Subsets in the Response to Influenza

2002 • 328 citations

The role of CD28 and cytotoxic T‐lymphocyte antigen‐4 (CTLA‐4) in regulatory T‐cell biology

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Immediate Cytotoxicity But Not Degranulation Distinguishes Effector and Memory Subsets of CD8+ T Cells

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Signaling Life and Death in the Thymus: Timing Is Everything

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Stress-induced enhancement of leukocyte trafficking into sites of surgery or immune activation

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Regulatory T Cells and Human Disease

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Selective expression of latency-associated peptide (LAP) and IL-1 receptor type I/II (CD121a/CD121b) on activated human FOXP3+ regulatory T cells allows for their purification from expansion cultures

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Human Virus-Specific CD8+ CTL Clones Revert from CD45ROhigh to CD45RAhigh In Vivo: CD45RAhighCD8+ T Cells Comprise Both Naive and Memory Cells

1999 • 173 citations

CD8 T cells specific for human immunodeficiency virus, Epstein-Barr virus, and cytomegalovirus lack molecules for homing to lymphoid sites of infection

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How psychological stress via hormones and nerve fibers may exacerbate rheumatoid arthritis

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Human regulatory T cells and autoimmunity

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Cardiovascular reactivity and the course of immune response to an acute psychological stressor.

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Acute stress evokes selective mobilization of T cells that differ in chemokine receptor expression: a potential pathway linking immunologic reactivity to cardiovascular disease

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Cutting Edge: L-Selectin (CD62L) Expression Distinguishes Small Resting Memory CD4+ T Cells That Preferentially Respond to Recall Antigen

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PSYCHONEUROIMMUNOLOGY

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ACUTE PSYCHOLOGICAL STRESS SIMULTANEOUSLY ALTERS HORMONE LEVELS, RECRUITMENT OF LYMPHOCYTE SUBSETS, AND PRODUCTION OF REACTIVE OXYGEN SPECIES

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Changes in immune regulation in response to examination stress in atopic and healthy individuals

2006 • 94 citations

Real-time RT-PCR for the Detection of Beta-adrenoceptor Messenger RNAs in Small Human Endomyocardial Biopsies

2001 • 76 citations

Glucocorticoid Receptor Isoforms α and β inin VitroCytokine-induced Glucocorticoid Insensitivity

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Acute psychological stress alerts the adaptive immune response: Stress-induced mobilization of effector T cells

2006 • 67 citations

CD4+CD25+FOXP3+ T regulatory cells reconstitute and accumulate in the bone marrow of patients with multiple myeloma following allogeneic stem cell transplantation

2008 • 64 citations

Acute psychological stress induces a prolonged suppression of the production of reactive oxygen species by phagocytes

2003 • 23 citations

Tregs and rheumatoid arthritis.

2008 • 19 citations

TGFβ1 deficiency does not affect the generation and maintenance of CD4+CD25+FOXP3+ putative Treg cells, but causes their numerical inadequacy and loss of regulatory function

2008 • 9 citations