A role for BRCA1 in sporadic breast cancer

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

STATISTICAL METHODS FOR ASSESSING AGREEMENT BETWEEN TWO METHODS OF CLINICAL MEASUREMENT

1986 • 45,881 citations

Measuring agreement in method comparison studies

1999 • 8,072 citations

Association of BRCA1 with Rad51 in Mitotic and Meiotic Cells

1997 • 1,466 citations

BRCA1 Mutations in Primary Breast and Ovarian Carcinomas

1994 • 1,205 citations

The Nottingham prognostic index in primary breast cancer

1992 • 1,051 citations

Dynamic Changes of BRCA1 Subnuclear Location and Phosphorylation State Are Initiated by DNA Damage

1997 • 910 citations

The Pathology of Familial Breast Cancer: Predictive Value of Immunohistochemical Markers Estrogen Receptor, Progesterone Receptor, HER-2, and p53 in Patients With Mutations in BRCA1 and BRCA2

2002 • 809 citations

The Tumor Suppressor Gene Brca1 Is Required for Embryonic Cellular Proliferation in the Mouse

1996 • 652 citations

Decreased expression of BRCA1 accelerates growth and is often present during sporadic breast cancer progression

1995 • 585 citations

Localization of human BRCA1 and its loss in high-grade, non-inherited breast carcinomas

1999 • 421 citations

BRCA1 protein is linked to the RNA polymerase II holoenzyme complex via RNA helicase A

1998 • 392 citations

The C-terminal (BRCT) Domains of BRCA1 Interact in Vivo with CtIP, a Protein Implicated in the CtBP Pathway of Transcriptional Repression

1998 • 383 citations

Somatic mutations in the BRCA1 gene in sporadic ovarian tumours

1995 • 377 citations

Growth retardation and tumour inhibition by BRCA1

1996 • 360 citations

The developmental pattern of Brca1 expression implies a role in differentiation of the breast and other tissues

1995 • 345 citations

Aberrant Subcellular Localization of BRCA1 in Breast Cancer

1995 • 310 citations

Aberrant methylation of the BRCA1 CpG island promoter is associated with decreased BRCA1 mRNA in sporadic breast cancer cells

1998 • 245 citations

Evaluating HER2 amplification and overexpression in breast cancer

2001 • 238 citations

Localization of BRCA1 and a Splice Variant Identifies the Nuclear Localization Signal

1997 • 233 citations

Differential subcellular localization, expression and biological toxicity of BRCA1 and the splice variant BRCA1-Δ11b

1997 • 195 citations

BRCA1 is secreted and exhibits properties of a granin

1996 • 184 citations

Hormone-dependent regulation of BRCA1 in human breast cancer cells.

1995 • 178 citations

Cell cycle regulation of BRCA1 messenger RNA in human breast epithelial cells.

1996 • 146 citations

High allele loss rates at I7q I2‐q2I in breast and ovarian tumors from BRCAI‐linked families

1995 • 122 citations

BRCA1 expression is not directly responsive to estrogen

1997 • 116 citations

Quantitative estimation of epidermal growth factor receptor and c-erbB-2 in human breast cancer.

1996 • 84 citations

Antisense RNA to the putative tumor suppressor gene BRCA1 transforms mouse fibroblasts.

1996 • 75 citations

The Functions of Breast Cancer Susceptibility Gene 1 (BRCA1) Product and Its Associated Proteins

1999 • 57 citations

Germ-line BRCA1 mutations in women with sporadic breast cancer: clinical correlations.

1998 • 37 citations

Quantitative radioimmunohistochemical measurements of p185(erbB-2) in frozen tissue sections.

1996 • 17 citations