Cyclooxygenase‐2 up‐regulation after FLAP transfection in human adenocarcinoma cell line HT29 cl.19A

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas

1994 • 2,553 citations

TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue

1991 • 1,814 citations

In situ detection of mycoplasma contamination in cell cultures by fluorescent Hoechst 33258 stain

1977 • 1,743 citations

Human cyclooxygenase-2 cDNA.

1992 • 1,493 citations

Prostaglandin synthase 2

1996 • 1,212 citations

Expression of cyclooxygenase-1 and -2 in human colorectal cancer.

1995 • 1,135 citations

Expression of prostaglandin G/H synthase-1 and -2 protein in human colon cancer.

1995 • 837 citations

Requirement of a 5-lipoxygenase-activating protein for leukotriene synthesis

1990 • 777 citations

Prostaglandin Endoperoxide H Synthases-1 and -2

1996 • 721 citations

Molecular cloning of human prostaglandin endoperoxide synthase type II and demonstration of expression in response to cytokines.

1993 • 710 citations

Different Intracellular Locations for Prostaglandin Endoperoxide H Synthase-1 and −2

1995 • 574 citations

Emergence of permanently differentiated cell clones in a human colonic cancer cell line in culture after treatment with sodium butyrate.

1984 • 532 citations

Structure of the mitogen-inducible TIS10 gene and demonstration that the TIS10-encoded protein is a functional prostaglandin G/H synthase.

1992 • 498 citations

Prostaglandin H synthase 2 is expressed abnormally in human colon cancer: evidence for a transcriptional effect.

1996 • 462 citations

Increased cyclooxygenase-2 levels in carcinogen-induced rat colonic tumors

1996 • 438 citations

Eicosanoids and the gastrointestinal tract

1995 • 426 citations

5-LIPOXYGENASE

1994 • 357 citations

Cloning of human gene encoding prostaglandin endoperoxide synthase and primary structure of the enzyme

1989 • 333 citations

Translocation of 5-lipoxygenase to the membrane in human leukocytes challenged with ionophore A23187.

1988 • 323 citations

MK886, a potent and specific leukotriene biosynthesis inhibitor blocks and reverses the membrane association of 5-lipoxygenase in ionophore-challenged leukocytes.

1990 • 319 citations

Prostaglandin H synthases, nonsteroidal antiinflammatory drugs, and colon cancer

1997 • 290 citations

The molecular biology of mammalian lipoxygenases and the quest for eicosanoid functions using lipoxygenase-deficient mice

1996 • 265 citations

5‐Lipoxygenase‐activating protein stimulates the utilization of arachidonic acid by 5‐lipoxygenase

1993 • 215 citations

N-glycosylation of prostaglandin endoperoxide synthases-1 and -2 and their orientations in the endoplasmic reticulum.

1993 • 211 citations

Correlation between expression of 5-lipoxygenase-activating protein, 5-lipoxygenase, and cellular leukotriene synthesis.

1990 • 191 citations

Transcriptional induction of prostaglandin G/H synthase-2 by basic fibroblast growth factor.

1995 • 144 citations

Cyclooxygenase-1 and cyclooxygenase-2 gene expression in human colorectal adenocarcinomas and in azoxymethane induced colonic tumours in rats.

1996 • 117 citations

Eosinophil-rich human polymorphonuclear leukocyte preparations characteristically release leukotriene C4 on ionophore A23187 challenge

1984 • 114 citations

Rapid Import of Cytosolic 5-Lipoxygenase into the Nucleus of Neutrophils after in Vivo Recruitment and in Vitro Adherence

1997 • 114 citations

Colocalization of Cytosolic Phospholipase A₂, 5‐Lipoxygenase, and 5‐Lipoxygenase‐Activating Protein at the Nuclear Membrane of A23187‐Stimulated Human Neutrophils

1996 • 106 citations

Bile acids, non‐phorbol‐ester‐type tumor promoters, stimulate the phosphorylation of protein kinase C substrates in human platelets and colon cell line HT29

1992 • 99 citations

Eicosanoid forming enzyme mRNA in human tissues. Analysis by quantitative polymerase chain reaction

1991 • 79 citations

5-Lipoxygenase-activating protein (FLAP)

1995 • 73 citations

Proteolytic activity is involved in changes in intrafollicular insulin-like growth factor-binding protein levels during growth and atresia of ovine ovarian follicles.

1996 • 68 citations

Role of Transcription Factor Egr-1 in Phorbol Ester-induced Phenylethanolamine N-Methyltransferase Gene Expression

1995 • 56 citations

Modulation of cellular phospholipid fatty acids and leukotriene B4 synthesis in the human intestinal cell (CaCo-2).

1992 • 53 citations

Translocation of HL-60 cell 5-lipoxygenase. Inhibition of A23187- or N-formyl-methionyl-leucyl-phenylalanine-induced translocation by indole and quinoline leukotriene synthesis inhibitors.

1991 • 49 citations

Proteolytic activity is involved in changes in intrafollicular insulin- like growth factor-binding protein levels during growth and atresia of ovine ovarian follicles

1996 • 31 citations

The 5-lipoxygenase pathway in cultured human intestinal epithelial cells

1995 • 25 citations

Cyclooxygenase-2 expression in human adenocarcinoma cell line HT29 cl.19A.

1998 • 19 citations

Production of arachidonic acid metabolites by the colon adenocarcinoma cell line HT29 cl.19A and their effect on chloride secretion

1997 • 16 citations

Linoleic acid peroxidation by Solanum tuberosum lipoxygenase was activated in the presence of human 5-lipoxygenase-activating protein

1998 • 7 citations

High efficiency capillary column-gas chromatography mass spectrometry : Analysis of the lipoxygenase pathway in eukaryot cells

1984 • 5 citations

Deleted Work

1955 • 0 citations