Expression of apoptosis-regulatory genes in epithelial cells in pulmonary fibrosis in mice

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation.

1992 • 9,540 citations

WAF1, a potential mediator of p53 tumor suppression

1993 • 8,360 citations

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death

1993 • 6,009 citations

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

1993 • 5,680 citations

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

1995 • 4,043 citations

Participation of p53 protein in the cellular response to DNA damage.

1991 • 3,818 citations

Bcl-2 functions in an antioxidant pathway to prevent apoptosis

1993 • 3,465 citations

bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

1993 • 3,111 citations

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

1993 • 2,969 citations

p53 is required for radiation-induced apoptosis in mouse thymocytes

1993 • 2,911 citations

Bcl-2 and the regulation of programmed cell death

1994 • 2,346 citations

WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis.

1994 • 2,025 citations

Wild-type p53 is a cell cycle checkpoint determinant following irradiation.

1992 • 1,877 citations

Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species

1993 • 1,692 citations

A novel form of Epstein-Barr virus latency in normal B cells in vivo

1995 • 1,552 citations

Molecular thanatopsis: a discourse on the BCL2 family and cell death

1996 • 1,412 citations

Cloning of Senescent Cell-Derived Inhibitors of DNA Synthesis Using an Expression Screen

1994 • 1,368 citations

DNA strand breaks: the DNA template alterations that trigger p53-dependent DNA damage response pathways.

1994 • 850 citations

Induction of WAF1/CIP1 by a p53-independent pathway.

1994 • 773 citations

Prevention of hypoxia-induced cell death by Bcl-2 and Bcl-xL

1995 • 611 citations

Bcl-XL and Bcl-2 repress a common pathway of cell death.

1995 • 406 citations

Regulation of Lymphocyte Survival by the BCL-2 Gene Family

1995 • 380 citations

Induction of bax by genotoxic stress in human cells correlates with normal p53 status and apoptosis.

1994 • 377 citations

P21Waf1/Cip1/Sdi1 and p53 expression in association with DNA strand breaks in idiopathic pulmonary fibrosis.

1996 • 329 citations

Relationship of alveolar epithelial injury and repair to the induction of pulmonary fibrosis.

1988 • 287 citations

Apoptosis and expression of Fas/Fas ligand mRNA in bleomycin-induced pulmonary fibrosis in mice.

1997 • 274 citations

p53-catalyzed annealing of complementary single-stranded nucleic acids.

1993 • 225 citations

Pcr in Situ Hybridization: Protocols and Applications

1997 • 208 citations

Repopulation of denuded tracheal grafts with normal, preneoplastic, and neoplastic epithelial cell populations.

1978 • 128 citations

The potential role of BAX and BCL-2 expression in diffuse alveolar damage.

1997 • 105 citations

Association of p53 and WAF1 expression with apoptosis in diffuse alveolar damage.

1996 • 83 citations

Expression of the BCL-2 protein in normal and dysplastic bronchial epithelium and in lung carcinomas

1995 • 61 citations

Gamma-radiation-induced cell death in the fetal rat brain possesses molecular characteristics of apoptosis and is associated with specific messenger RNA elevations

1996 • 47 citations

PCR In Situ Hybridization. Protocols and Applications

1995 • 22 citations