Back to search

Targeting an antioxidant to mitochondria decreases cardiac ischemia‐reperfusion injury

Data up to Jan 2025

Published2005
Citations581
References39

Total Citations Per Year

Abstract

References (39)

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Methods of Enzymatic Analysis

1975 • 20,446 citations

Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide.

1990 • 7,068 citations

Mitochondrial Diseases in Man and Mouse

1999 • 3,008 citations

4 Lactate Dehydrogenase

1975 • 1,272 citations

Direct measurement of free radical generation following reperfusion of ischemic myocardium.

1987 • 1,185 citations

Mitochondria, oxygen free radicals, disease and ageing

2000 • 1,054 citations

Selective Targeting of a Redox-active Ubiquinone to Mitochondria within Cells

2001 • 1,025 citations

Delivery of bioactive molecules to mitochondria in vivo

2003 • 669 citations

UV-Assay with Pyruvate and NADH

1974 • 580 citations

Role of the Mitochondrial Permeability Transition in Myocardial Disease

2003 • 575 citations

Decrease in Mitochondrial Complex I Activity in Ischemic/Reperfused Rat Heart

2003 • 429 citations

Drug delivery to mitochondria: the key to mitochondrial medicine

2000 • 415 citations

The role of iron in the activation-inactivation of aconitase.

1983 • 379 citations

Overexpression of MnSOD Protects Against Myocardial Ischemia/reperfusion Injury in Transgenic Mice

1998 • 351 citations

Mitochondria‐targeted antioxidants protect Friedreich Ataxia fibroblasts from endogenous oxidative stress more effectively than untargeted antioxidants

2003 • 349 citations

Selective targeting of bioactive compounds to mitochondria

1997 • 344 citations

Conversion of biomembrane-produced energy into electric form. I. Submitochondrial particles

1970 • 321 citations

Mitochondrial Aconitase Is a Source of Hydroxyl Radical

2000 • 306 citations

Supplementation of Endothelial Cells with Mitochondria-targeted Antioxidants Inhibit Peroxide-induced Mitochondrial Iron Uptake, Oxidative Damage, and Apoptosis

2004 • 233 citations

Inhibition of mitochondrial permeability transition prevents mitochondrial dysfunction, cytochrome c release and apoptosis induced by heart ischemia

2003 • 192 citations

Fine‐tuning the hydrophobicity of a mitochondria‐targeted antioxidant

2004 • 179 citations

Altered mitochondrial function in fibroblasts containing MELAS or MERRF mitochondrial DNA mutations

1996 • 165 citations

Antioxidants in myocardial ischemia–reperfusion injury: therapeutic potential and basic mechanisms

2003 • 162 citations

Heat Shock Protein 72 Enhances Manganese Superoxide Dismutase Activity During Myocardial Ischemia-Reperfusion Injury, Associated With Mitochondrial Protection and Apoptosis Reduction

2002 • 142 citations

Prevention of Mitochondrial Oxidative Damage Using Targeted Antioxidants

2002 • 130 citations

Reoxygenation-dependent decrease in mitochondrial NADH:CoQ reductase (Complex I) activity in the hypoxic/reoxygenated rat heart

1991 • 126 citations

Postischemic Recovery of Contractile Function is Impaired in SOD2 +/− but Not SOD1 +/− Mouse Hearts

2002 • 124 citations

Ischemia–reperfusion injury in the aged heart: role of mitochondria

2003 • 114 citations

Lifespan and mitochondrial control of neurodegeneration

2004 • 103 citations

Mitochondria. A practical approach

1988 • 96 citations

Release of mitochondrial cytochrome c and activation of cytosolic caspases induced by myocardial ischaemia

2001 • 96 citations

Heat Stress Contributes to the Enhancement of Cardiac Mitochondrial Complex Activity

2001 • 91 citations

Neuroprotective effects of spermine following hypoxia‐ischemia‐induced brain damage: A mechanistic study

2004 • 70 citations

How understanding the control of energy metabolism can help investigation of mitochondrial dysfunction, regulation and pharmacology

2001 • 55 citations

Water content and its intracellular distribution in intact and saline perfused rat hearts revisited

2002 • 52 citations

Cardiac ischemia/reperfusion, aging, and redox-dependent alterations in mitochondrial function

2003 • 51 citations

Effects of 6-(.OMEGA.-substituted alkyl)-2,3-dimethoxy-5-methyl-1,4-benzoquinones and related compounds on mitochondrial succinate and reduced nicotinamide adenine dinucleotide oxidase systems.

1985 • 41 citations

Mitochondrial membrane potentials in ischemic hearts

2003 • 33 citations

Cited By (0)

Loading...
Targeting an antioxidant to mitochondria decreases cardiac ischemia‐reperfusion injury (2005) – The FASEB Journal | Metascience Observatory Explorer