Heat Stress Contributes to the Enhancement of Cardiac Mitochondrial Complex Activity

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Heme oxygenase 1 is required for mammalian iron reutilization

1997 • 998 citations

Bilirubin, formed by activation of heme oxygenase-2, protects neurons against oxidative stress injury

1999 • 694 citations

Mitochondrial disease in superoxide dismutase 2 mutant mice

1999 • 581 citations

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1997 • 432 citations

Effect of reperfusion late in the phase of reversible ischemic injury. Changes in cell volume, electrolytes, metabolites, and ultrastructure.

1985 • 388 citations

Heat shock proteins: regulators of stress response and apoptosis

1998 • 300 citations

Bimoclomol: A nontoxic, hydroxylamine derivative with stress protein-inducing activity and cytoprotective effects

1997 • 280 citations

The Biological Significance and Physiological Role of Heme Oxygenase

1996 • 254 citations

Carbon monoxide is a major contributor to the regulation of vascular tone in aortas expressing high levels of haeme oxygenase‐1

1998 • 239 citations

Functional Interaction of Cytosolic hsp70 and a DnaJ-Related Protein, Ydj1p, in Protein Translocation In Vivo

1996 • 235 citations

Mitochondrial structure and function in acute myocardial ischemic injury.

1976 • 234 citations

Downregulation of Immunodetectable Connexin43 and Decreased Gap Junction Size in the Pathogenesis of Chronic Hibernation in the Human Left Ventricle

1998 • 217 citations

Bilirubin Is an Effective Antioxidant of Peroxynitrite-Mediated Protein Oxidation in Human Blood Plasma

1998 • 212 citations

Threshold Effects and Control of Oxidative Phosphorylation in Nonsynaptic Rat Brain Mitochondria

1996 • 204 citations

The protective role of heat stress in the ischaemic and reperfused rabbit myocardium

1992 • 174 citations

In vivo gene transfection with heat shock protein 70 enhances myocardial tolerance to ischemia-reperfusion injury in rat.

1997 • 170 citations

Differential Expression of Heat Shock Proteins in Normal and Failing Human Hearts

1998 • 167 citations

Active unfolding of precursor proteins during mitochondrial protein import

1997 • 159 citations

Frequency and specificity of antiheart antibodies in patients with dilated cardiomyopathy detected using SDS-PAGE and western blotting

1993 • 158 citations

Studies on partially reduced mammalian cytochrome oxidase. Reactions with carbon monoxide and oxygen

1974 • 154 citations

Mitochondrial heat shock protein 70, a molecular chaperone for proteins encoded by mitochondrial DNA.

1994 • 143 citations

Global ischaemia induces a biphasic response of the mitochondrial respiratory chain. Anoxic pre-perfusion protects against ischaemic damage

1992 • 141 citations

Whole-Body Hyperthermia Provides Biphasic Cardioprotection Against Ischemia/Reperfusion Injury in the Rat

1998 • 127 citations

Simultaneous Overexpression of Two Stress Proteins in Rat Cardiomyocytes and Myogenic Cells Confers Protection Against Ischemia-Induced Injury

1997 • 117 citations

Effects of 1‐Methyl‐4‐Phenylpyridinium on Isolated Rat Brain Mitochondria: Evidence for a Primary Involvement of Energy Depletion

1994 • 104 citations

Control and kinetic analysis of ischemia-damaged heart mitochondria: which parts of the oxidative phosphorylation system are affected by ischemia?

1995 • 97 citations

Transcriptional regulation of the heme oxygenase 1 gene by pyrrolidine dithiocarbamate

1998 • 96 citations

HSP70 Induction in the Brain Following Ethanol Administration in the Rat: Regulation by Glutathione Redox State

2000 • 91 citations

The other human genome: Mitochondrial DNA and disease

1996 • 81 citations

On the role of the general transcription factor Sp1 in the activation and repression of diverse mammalian oxidative phosphorylation genes.

1999 • 78 citations

Heat Shock-induced Manganese Superoxide Dismutase Enhances the Tolerance of Cardiac Myocytes to Hypoxia–Reoxygenation Injury

1997 • 71 citations

Gene Therapy for Myocardial Protection : Transfection of Donor Hearts With Heat Shock Protein 70 Gene Protects Cardiac Function Against Ischemia-Reperfusion Injury

2000 • 69 citations

Metabolic Disturbances During Myocardial Ischemia and Reperfusion

1995 • 67 citations

Relation between left ventricular function and oxidative stress in patients undergoing bypass surgery

1998 • 58 citations

The alpha regulatory subunit of the mitochondrial F1-ATPase complex is a heat-shock protein. Identification of two highly conserved amino acid sequences among the alpha-subunits and molecular chaperones.

1990 • 49 citations

Differential Expression of Connexin43 and Desmin Defines Two Subpopulations of Medial Smooth Muscle Cells in the Human Internal Mammary Artery

1999 • 45 citations

Induction of heat-shock proteins enhances myocardial and endothelial functional recovery after prolonged cardioplegic arrest

1994 • 43 citations

TIME-DEPENDENT IMPAIRMENT OF MITOCHONDRIAL FUNCTION AFTER STORAGE AND TRANSPLANTATION OF RABBIT KIDNEYS1

2000 • 43 citations

Postnatal Development of the Complexes of the Electron Transport Chain in Synaptic Mitochondria from Rat Brain

1995 • 43 citations

Impairment of Hepatic Mitochondrial Respiratory Function Following Storage and Orthotopic Transplantation of Rat Livers

1998 • 41 citations

Kinetics of induction and protective effect of heat-shock proteins after cardioplegic arrest

1996 • 36 citations

Endogenously produced peroxynitrite induces the oxidation of mitochondrial and nuclear proteins in immunostimulated macrophages

1997 • 35 citations

The chaperonin‐related protein Tcm62p ensures mitochondrial gene expresssion under heat stress

2000 • 31 citations

Biphasic Effect of Heat Stress Pretreatment on Ischemic Tolerance of Isolated Rat Hearts

1998 • 30 citations

Ischemia decreases the content of the adenine nucleotide translocator in mitochondria of rat kidney

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Mitochondrial myopathies: genetic defects

1990 • 22 citations

Heat shock improves ischemic tolerance of hypertrophied rat hearts

1994 • 21 citations

Heat stress pretreatment mitigates postischemic arachidonic acid accumulation in rat heart.

1998 • 21 citations

Changes in Calcium Uptake Rate by Rat Cardiac Mitochondria during Postnatal Development

1998 • 20 citations

Influence of heat stress on myocardial metabolism and functional recovery after cardioplegic arrest: a 31P N.M.R study1

1998 • 19 citations

Mitochondrial myopathies: clinical defects

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The molecular basis of adaptation to ischemia in the heart: The role of stress proteins and anti-oxidants in the ischemic and reperfused heart

1996 • 15 citations

Influence of intracellular pH on mitochondrial calcium during ischaemia of the isolated rat heart

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Reduction of cytochrome c by fragments of heat shock protein 70

1993 • 10 citations

Reduced purine catabolite production in the postischemic rat heart: a31P NMR assessment of cytosolic metabolites

1994 • 10 citations