Regulatory T cells facilitate the nuclear accumulation of inducible cAMP early repressor (ICER) and suppress nuclear factor of activated T cell c1 (NFATc1)

CD4+CD25+ Immunoregulatory T Cells Suppress Polyclonal T Cell Activation In Vitro by Inhibiting Interleukin 2 Production

1998 • 2,658 citations

Transcriptional regulation by calcium, calcineurin, and NFAT

2003 • 1,893 citations

FOXP3 Controls Regulatory T Cell Function through Cooperation with NFAT

2006 • 1,135 citations

Regulatory T cells exert checks and balances on self tolerance and autoimmunity

2009 • 1,079 citations

The Foxp3+ regulatory T cell: a jack of all trades, master of regulation

2008 • 999 citations

Selective depletion of Foxp3+ regulatory T cells induces a scurfy-like disease

2007 • 887 citations

Cyclic adenosine monophosphate is a key component of regulatory T cell–mediated suppression

2007 • 618 citations

A Low Interleukin-2 Receptor Signaling Threshold Supports the Development and Homeostasis of T Regulatory Cells

2009 • 250 citations

Defective thymocyte proliferation and IL-2 production in transgenic mice expressing a dominant-negative form of CREB

1996 • 249 citations

Autoregulation of NFATc1/A Expression Facilitates Effector T Cells to Escape from Rapid Apoptosis

2002 • 194 citations

NFATc2 and NFATc3 transcription factors play a crucial role in suppression of CD4+ T lymphocytes by CD4+ CD25+ regulatory T cells

2005 • 142 citations

Role of Transcriptional Repressor ICER in Cyclic AMP-mediated Attenuation of Cytokine Gene Expression in Human Thymocytes

1998 • 112 citations

Sumoylation of the Transcription Factor NFATc1 Leads to Its Subnuclear Relocalization and Interleukin-2 Repression by Histone Deacetylase

2009 • 104 citations

Inhibition of cAMP Degradation Improves Regulatory T Cell-Mediated Suppression

2009 • 89 citations

Antisense Cyclic Adenosine 5′-Monophosphate Response Element Modulator Up-Regulates IL-2 in T Cells from Patients with Systemic Lupus Erythematosus

2002 • 89 citations

Rapid Regulatory T-Cell Response Prevents Cytokine Storm in CD28 Superagonist Treated Mice

2009 • 80 citations

Protection from graft-versus-host disease by HIV-1 envelope protein gp120-mediated activation of human CD4+CD25+ regulatory T cells

2009 • 76 citations

Suppression of T-cell responsiveness by inducible cAMP early repressor (ICER)

2001 • 66 citations

ICER/CREM‐mediated transcriptional attenuation of IL‐2 and its role in suppression by regulatory T cells

2007 • 66 citations

Mitogen-activated Protein Kinase Phosphorylates and Targets Inducible cAMP Early Repressor to Ubiquitin-mediated Destruction

2001 • 46 citations

Epigenetic Changes and Suppression of the Nuclear Factor of Activated T Cell 1 (NFATC1) Promoter in Human Lymphomas with Defects in Immunoreceptor Signaling

2007 • 42 citations

Flow cytometry analysis of gap junction‐mediated cell–cell communication: Advantages and pitfalls

2006 • 41 citations

Regulation of the NFAT pathway discriminates CD4+CD25+ regulatory T cells from CD4+CD25− helper T cells

2007 • 33 citations