Iron regulatory elements (IREs): a family of mRNA non-coding sequences

Transcription Factor Interactions: Selectors of Positive or Negative Regulation from a Single DNA Element

1990 • 1,326 citations

Regulating the fate of mRNA: The control of cellular iron metabolism

1993 • 1,233 citations

Iron-Responsive Elements: Regulatory RNA Sequences That Control mRNA Levels and Translation

1988 • 707 citations

A stem-loop in the 3′ untranslated region mediates iron-dependent regulation of transferrin receptor mRNA stability in the cytoplasm

1988 • 565 citations

Identification of the Iron-Responsive Element for the Translational Regulation of Human Ferritin mRNA

1987 • 547 citations

MINIREVIEW: The Steroid Receptor Superfamily: More Excitement Predicted for the Future

1990 • 489 citations

RIBOSOMAL RNA AND TRANSLATION

1991 • 489 citations

The Second Sir Hans Krebs Lecture

2005 • 397 citations

Human erythroid 5-aminolevulinate synthase: promoter analysis and identification of an iron-responsive element in the mRNA.

1991 • 374 citations

Gene regulation of plasmid- and chromosome-determined inorganic ion transport in bacteria

1992 • 369 citations

Iron regulates ferritin mRNA translation through a segment of its 5' untranslated region.

1987 • 365 citations

Visualizing the Higher Order Folding of a Catalytic RNA Molecule

1991 • 354 citations

Identification of a novel iron-responsive element in murine and human erythroid delta-aminolevulinic acid synthase mRNA.

1991 • 349 citations

Purification and characterization of cytosolic aconitase from beef liver and its relationship to the iron-responsive element binding protein.

1992 • 345 citations

Regulation of ferritin and transferrin receptor mRNAs.

1990 • 339 citations

Novel mechanism for translational control in regulation of ferritin synthesis by iron.

1976 • 324 citations

Cellular regulation of the iron-responsive element binding protein: disassembly of the cubane iron-sulfur cluster results in high-affinity RNA binding.

1992 • 324 citations

mRNA decay: Finding the right targets

1989 • 318 citations

Mechanism of action of regulatory proteins encoded by complex retroviruses

1992 • 299 citations

A cytosolic protein binds to structural elements within the iron regulatory region of the transferrin receptor mRNA.

1989 • 244 citations

Engineering of protein bound iron‐sulfur clusters

1989 • 211 citations

Translational control of 5-aminolevulinate synthase mRNA by iron-responsive elements in erythroid cells.

1993 • 210 citations

Cloning of the cDNA encoding an RNA regulatory protein--the human iron-responsive element-binding protein.

1990 • 205 citations

Ferritin gene transcription is regulated by iron in soybean cell cultures.

1991 • 183 citations

Genetics of the iron dicitrate transport system of Escherichia coli

1988 • 180 citations

Evidence for conservation of ferritin sequences among plants and animals and for a transit peptide in soybean.

1990 • 168 citations

Differences in the regulation of messenger RNA for housekeeping and specialized-cell ferritin. A comparison of three distinct ferritin complementary DNAs, the corresponding subunits, and identification of the first processed in amphibia.

1987 • 156 citations

A phylogenetically conserved sequence within viral 3' untranslated RNA pseudoknots regulates translation.

1993 • 153 citations

Translational repression by a complex between the iron-responsive element of ferritin mRNA and its specific cytoplasmic binding protein is position-dependent in vivo.

1990 • 147 citations

Purification of a Specific Repressor of Ferritin mRNA Translation from Rabbit Liver

1989 • 138 citations

Site-specific cleavage of RNA by Fe(II).bleomycin.

1990 • 130 citations

The half-life of c-myc mRNA in growing and serum-stimulated cells: influence of the coding and 3' untranslated regions and role of ribosome translocation.

1994 • 129 citations

Iron-responsive element-binding protein. Phosphorylation by protein kinase C.

1993 • 128 citations

Control of mRNA Stability in Higher Plants

1993 • 127 citations

The mRNA-binding protein which controls ferritin and transferrin receptor expression is conserved during evolution

1990 • 125 citations

Structural requirements of iron-responsive elements for binding of the protein involved in both transferrin receptor and ferritin mRNA post-transcriptional regulation

1990 • 114 citations

Translational control of ferritin synthesis by iron in embryonic reticulocytes of the bullfrog.

1982 • 104 citations

The putative iron-responsive element in the human erythroid 5-aminolevulinate synthase mRNA mediates translational control

1993 • 103 citations

[11] Using hydroxyl radical to probe DNA structure

1992 • 100 citations

Translational control of gene expression in a normal fibroblast. Characterization of a subclass of mRNAs with unusual kinetic properties

1986 • 98 citations

Characterization and evolution of the expressed rat ferritin light subunit gene and its pseudogene family. Conservation of sequences within noncoding regions of ferritin genes.

1987 • 95 citations

Ferritin mRNA: interactions of iron regulatory element with translational regulator protein P-90 and the effect on base-paired flanking regions.

1991 • 95 citations

Unification of the ferritin family of proteins.

1992 • 94 citations

Nucleotide sequence and structural determinants of specific binding of coat protein or coat protein peptides to the 3' untranslated region of alfalfa mosaic virus RNA 4

1994 • 90 citations

The importance of the 3'-untranslated region in the translational control of ferritin mRNA.

1988 • 84 citations

The iron-responsive element binding protein. Purification, cloning, and regulation in rat liver.

1992 • 78 citations

Transferrin receptor gene expression during rat liver regeneration. Evidence for post-transcriptional regulation by iron regulatory factorB, a second iron-responsive element-binding protein.

1994 • 76 citations

Multiple red cell ferritin mRNAs, which code for an abundant protein in the embryonic cell type, analyzed by cDNA sequence and by primer extension of the 5'-untranslated regions.

1986 • 68 citations

Structure of the 5' untranslated regulatory region of ferritin mRNA studied in solution

1990 • 67 citations

Recognition of tertiary structure in tRNAs by Rh(phen)2phi3+, a new reagent for RNA structure-function mapping

1992 • 66 citations

The Influence of the Base-paired Flanking region on Structure and Function of the Ferritin mRNA Iron Regulatory Element

1993 • 66 citations

Scission of RNA by the chemical nuclease of 1,10-phenanthroline-eopper ion: preference for single-stranded loops

1989 • 64 citations

The iron regulatory region of ferritin mRNA is also a positive control element for iron-independent translation

1992 • 63 citations

The IRE (iron regulatory element) family: structures which regulate mRNA translation or stability.

1993 • 57 citations

Differential regulation of iron regulatory element-binding protein(s) in cell extracts of activated lymphocytes versus monocytes-macrophages

1991 • 57 citations

Cloning of a functional cDNA for the rabbit ferritin mRNA repressor protein. Demonstration of a tissue-specific pattern of expression.

1992 • 56 citations

A Phylogenetically Conserved Sequence within Viral 3' Untranslated RNA Pseudoknots Regulates Translation

1993 • 51 citations

Regulation of ferritin mRNA: a possible gene-sparing phenomenon. Induction of ferritin synthesis by iron in liver as well as red cells combines high translational efficiency with increased utilization of preformed ferritin mRNA.

1983 • 47 citations

Posttranscriptional Regulation of Ferritin during Nodule Development in Soybean

1994 • 44 citations

Iron Chelation in Plants and Soil Microorganisms

1993 • 43 citations

Translationaj repression by the human iron-regulatory factor (IRF) in Saccharomyces cerevisiae

1993 • 39 citations

The effect of iron on the synthesis and amount of ferritin in red blood cells during ontogeny.

1981 • 36 citations

The Half-Life of c-myc mRNA in Growing and Serum-Stimulated Cells: Influence of the Coding and 3′ Untranslated Regions and Role of Ribosome Translocation

1994 • 36 citations

Regulation of Gene Expression by Steroid Hormones

1992 • 32 citations

Ferritin synthesis is controlled by iron-dependent translational derepression and by changes in synthesis/transport of nuclear ferritin RNAs.

1993 • 31 citations