The Half-Life of c-myc mRNA in Growing and Serum-Stimulated Cells: Influence of the Coding and 3′ Untranslated Regions and Role of Ribosome Translocation

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

RNA molecular weight determinations by gel electrophoresis under denaturing conditions, a critical reexamination

1977 • 3,548 citations

Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene

1984 • 3,150 citations

Various rat adult tissues express only one major mRNA species from the glyceraldehyde-3-phosphate-dehydrogenase multigenic family

1985 • 2,145 citations

Platelet-derived growth factor induces rapid but transient expression of the c-fos gene and protein

1984 • 949 citations

Transient accumulation of c-fos RNA following serum stimulation requires a conserved 5′ element and c-fos 3′ sequences

1985 • 871 citations

Plasmid-encoded hygromycin B resistance: the sequence of hygromycin B phosphotransferase gene and its expression in Escherichia coli and Saccharomyces cerevisiae

1983 • 810 citations

THE myc ONCOGENE: ITS ROLE IN TRANSFORMATION AND DIFFERENTIATION

1986 • 714 citations

Control of c-myc Regulation in Normal and Neoplastic Cells

1991 • 632 citations

The c-fos transcript is targeted for rapid decay by two distinct mRNA degradation pathways.

1989 • 601 citations

A stem-loop in the 3′ untranslated region mediates iron-dependent regulation of transferrin receptor mRNA stability in the cytoplasm

1988 • 565 citations

Two distinct destabilizing elements in the c-fos message trigger deadenylation as a first step in rapid mRNA decay.

1991 • 546 citations

The nucleotide sequence of the human β-globin gene

1980 • 502 citations

An A + U-rich element RNA-binding factor regulates c-myc mRNA stability in vitro.

1991 • 484 citations

New light on Myc and Myb. Part I. Myc.

1990 • 325 citations

Control of c-myc mRNA half-life in vitro by a protein capable of binding to a coding region stability determinant.

1992 • 301 citations

The protein-coding region of c-myc mRNA contains a sequence that specifies rapid mRNA turnover and induction by protein synthesis inhibitors.

1991 • 297 citations

A precursor of globin messenger RNA

1976 • 254 citations

Rapid cytoplasmic turnover of c-myc mRNA: requirement of the 3' untranslated sequences.

1987 • 182 citations

H4 histone messenger RNA decay in cell-free extracts initiates at or near the 3′ terminus and proceeds 3′ to 5′

1986 • 179 citations

A comparison of apparent mRNA half-life using kinetic labeling techniques vs decay following administration of transcriptional inhibitors

1991 • 114 citations

Transfection of mouse erythroleukemia cells with myc sequences changes the rate of induced commitment to differentiate.

1986 • 112 citations

Half-lives of beta and gamma globin messenger RNAs and of protein synthetic capacity in cultured human reticulocytes

1985 • 108 citations

Phosphorothioate analogs of 2',5'-oligoadenylate. Enzymatically synthesized 2',5'-phosphorothioate dimer and trimer: unequivocal structural assignment and activation of 2',5'-oligoadenylate-dependent endoribonuclease

1987 • 57 citations

Translation of c-myc mRNA is required for its post-transcriptional regulation during myogenesis.

1990 • 54 citations

Phosphorothioate analogs of 2',5'-oligoadenylate. Activation of 2',5'-oligoadenylate-dependent endoribonuclease by 2',5'-phosphorothioate cores and 5'-monophosphates

1987 • 44 citations

Cleavage of nascent reovirus mRNA by localized activation of the 2'-5'-oligoadenylate-dependent endoribonuclease

1984 • 43 citations

Rapidc-mycmRNA degradation does not require (A + U)-rich sequences or complete translation of the mRNA

1991 • 43 citations

Enhancement of RNA polymerase II initiation complexes by a novel DNA control domain downstream from the cap site of the cytomegalovirus major immediate-early promoter

1991 • 41 citations

Phosphorothioate analogs of 2',5'-oligoadenylate. Enzymic synthesis, properties, and biological activities of 2',5'-phosphorothioates from adenosine 5'-O-(2-thiotriphosphate) and adenosine 5'-O-(3-thiotriphosphate)

1987 • 25 citations

The myb and myc nuclear oncogenes as transcriptional activators

1990 • 16 citations