Endostatin Causes G1 Arrest of Endothelial Cells through Inhibition of Cyclin D1

Cancer Cell Cycles

1996 • 5,379 citations

Endostatin: An Endogenous Inhibitor of Angiogenesis and Tumor Growth

1997 • 4,504 citations

β-Catenin regulates expression of cyclin D1 in colon carcinoma cells

1999 • 3,566 citations

The cyclin D1 gene is a target of the β-catenin/LEF-1 pathway

1999 • 2,206 citations

Expression of achaete-scute homolog 3 in Xenopus embryos converts ectodermal cells to a neural fate.

1994 • 1,032 citations

A stable human-derived packaging cell line for production of high titer retrovirus/vesicular stomatitis virus G pseudotypes.

1996 • 925 citations

Endostatin Induces Endothelial Cell Apoptosis

1999 • 594 citations

Mammalian G1- and S-phase checkpoints in response to DNA damage

2001 • 560 citations

Endostatin inhibits VEGF-induced endothelial cell migration and tumor growth independently of zinc binding

1999 • 451 citations

Interaction of endostatin with integrins implicated in angiogenesis

2001 • 442 citations

The Cyclins and Cyclin-Dependent Kinase Inhibitors in Hormonal Regulation of Proliferation and Differentiation*

1999 • 358 citations

Cell Surface Glypicans Are Low-Affinity Endostatin Receptors

2001 • 310 citations

Endostatin: yeast production, mutants, and antitumor effect in renal cell carcinoma.

1999 • 246 citations

Identification of a Myc-dependent step during the formation of active G1 cyclin-cdk complexes.

1995 • 243 citations

Antisense to cyclin D1 inhibits the growth and tumorigenicity of human colon cancer cells.

1997 • 227 citations

Myc induces cyclin D1 expression in the absence of de novo protein synthesis and links mitogen-stimulated signal transduction to the cell cycle.

1994 • 227 citations

Structural basis and potential role of heparin/heparan sulfate binding to the angiogenesis inhibitor endostatin

1999 • 214 citations

Antiangiogenesis signals by endostatin

2001 • 198 citations

Cloning, Expression, andin VitroActivity of Human Endostatin

1999 • 188 citations

Inhibition of Cyclin D1 Kinase Activity Is Associated with E2F-Mediated Inhibition of Cyclin D1 Promoter Activity through E2F and Sp1

1998 • 160 citations

Inhibition of basal and mitogen-stimulated pancreatic cancer cell growth by cyclin D1 antisense is associated with loss of tumorigenicity and potentiation of cytotoxicity to cisplatinum.

1998 • 145 citations

Antisense to cyclin D1 inhibits growth and reverses the transformed phenotype of human esophageal cancer cells.

1995 • 143 citations

TCF Is the Nuclear Effector of the β-Catenin Signal That Patterns the Sea Urchin Animal–Vegetal Axis

2000 • 137 citations

Inhibition of cyclin D1 expression in human pancreatic cancer cells is associated with increased chemosensitivity and decreased expression of multiple chemoresistance genes.

1999 • 114 citations

Antisense cyclin D1 induces apoptosis and tumor shrinkage in human squamous carcinomas.

1999 • 113 citations

Transcriptional Activation of the cyclin D1 Gene Is Mediated by Multiple Cis-Elements, Including SP1 Sites and a cAMP-responsive Element in Vascular Endothelial Cells

2001 • 97 citations

Antiangiogenesis signals by endostatin

2001 • 64 citations

Requirement of Cyclin D1 in Mesangial Cell Mitogenesis

2000 • 24 citations

Cyclin D1 Antisense Oligonucleotide Inhibits Cell Growth Stimulated by Epidermal Growth Factor and Induces Apoptosis of Gastric Cancer Cells

2001 • 20 citations