Expression and characterization of the product of a human immune interferon cDNA gene in Chinese hamster ovary cells.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Rapid Isolation of Antigens from Cells with A Staphylococcal Protein A-Antibody Adsorbent: Parameters of the Interaction of Antibody-Antigen Complexes with Protein A

1975 • 3,054 citations

Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter.

1982 • 2,753 citations

Transformation of mammalian cells with genes from procaryotes and eucaryotes

1979 • 1,474 citations

Isolation of Chinese hamster cell mutants deficient in dihydrofolate reductase activity.

1980 • 903 citations

Expression of human immune interferon cDNA in E. coli and monkey cells

1982 • 703 citations

Transformation of rat cells by DNA of human adenovirus 5

1973 • 664 citations

Inhibition of SV40 replication in simian cells by specific pBR322 DNA sequences

1981 • 657 citations

Identification of DNA sequences required for transcription of the human α1-globin gene in a new SV40 host-vector system

1981 • 624 citations

Evidence that types I and II interferons have different receptors

1981 • 511 citations

Amplified dihydrofolate reductase genes are localized to a homogeneously staining region of a single chromosome in a methotrexate-resistant Chinese hamster ovary cell line.

1978 • 393 citations

Improved plasmid vectors with a thermoinducible expression and temperature-regulated runaway replication

1983 • 362 citations

Amplification and expression of sequences cotransfected with a modular dihydrofolate reductase complementary DNA gene

1982 • 356 citations

Expression of the mouse dihydrofolate reductase complementary deoxyribonucleic acid in simian virus 40 vectors.

1981 • 303 citations

Isolation and structure of a human fibroblast interferon gene

1980 • 300 citations

Differential efficacies of human type I and type II interferons as antiviral and antiproliferative agents.

1980 • 286 citations

Human leukocyte and fibroblast interferons are structurally related

1980 • 273 citations

Purified human immune interferon has more potent anticellular activity than fibroblast or leukocyte interferon

1980 • 221 citations

Molecular cloning of human immune interferon cDNA and its expression in eukaryotic cells

1982 • 192 citations

Correlation of dihydrofolate reductase elevation with gene amplification in a homogeneously staining chromosomal region in L5178Y cells.

1979 • 185 citations

The nucleotide sequence of a cloned human leukocyte Interferon cDNA

1980 • 158 citations

Transformation of mammalian cells with an amplifiable dominant-acting gene.

1980 • 158 citations

Large-scale production and physicochemical characterization of human immune interferon

1979 • 147 citations

Construction of a modular dihydrofolate reductase cDNA gene: analysis of signals utilized for efficient expression.

1982 • 145 citations

Partial purification and characterization of human gamma (immune) interferon.

1981 • 145 citations

Some Properties of Virus and Immune-Induced Human Lymphocyte Interferons

1972 • 103 citations

Inhibition of Murine Osteogenic Sarcomas by Treatment With Type I or Type II Interferon<xref ref-type="fn" rid="FN2">2</xref>

1978 • 101 citations

Immune (γ) interferon produced by a human T-lymphoblast cell line

1981 • 99 citations

Time and dosoge dependence of immunoenhancement by murine type II interferon preparations

1978 • 96 citations

Expression of the Mouse Dihydrofolate Reductase Complementary Deoxyribonucleic Acid in Simian Virus 40 Vectors

1981 • 96 citations

Purification of two subspecies of human gamma (immune) interferon.

1982 • 90 citations

Co-expression and amplification of dihydrofolate reductase cDNA and the Escherichia coli XGPRT gene in Chinese hamster ovary cells.

1981 • 75 citations

Gene amplification in methotrexate-resistant mouse cells

1981 • 66 citations

Construction of a Modular Dihydrofolate Reductase cDNA Gene: Analysis of Signals Utilized for Efficient Expression

1982 • 51 citations

Inferferon induced in human leukocytes by concanavalin A: isolation and characterization of γ‐ and β‐type components

1981 • 51 citations

Monoclonal antibody against human IFN-γ

1982 • 47 citations

Interferon-gamma: success, structure and speculation

1982 • 34 citations

Isolation and Characterization of IFN-Gamma mRNA Derived from Mitogen-Induced Human Splenocytes

1982 • 14 citations

Interferon redux

1982 • 2 citations