p21CIP1 and p57KIP2 control muscle differentiation at the myogenin step

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

1993 • 5,680 citations

The retinoblastoma protein and cell cycle control

1995 • 4,873 citations

Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

1995 • 2,115 citations

Effects of an Rb mutation in the mouse

1992 • 1,779 citations

Mice Lacking p27 Display Increased Body Size, Multiple Organ Hyperplasia, Retinal Dysplasia, and Pituitary Tumors

1996 • 1,583 citations

Role of the INK4a Locus in Tumor Suppression and Cell Mortality

1996 • 1,580 citations

A Syndrome of Multiorgan Hyperplasia with Features of Gigantism, Tumorigenesis, and Female Sterility in p27 -Deficient Mice

1996 • 1,488 citations

Muscle deficiency and neonatal death in mice with a targeted mutation in the myogenin gene

1993 • 1,314 citations

Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis

1992 • 1,285 citations

Enhanced Growth of Mice Lacking the Cyclin-Dependent Kinase Inhibitor Function of p27

1996 • 1,283 citations

Correlation of Terminal Cell Cycle Arrest of Skeletal Muscle with Induction of p21 by MyoD

1995 • 1,154 citations

p53-Independent Expression of p21 ^Cip1 in Muscle and Other Terminally Differentiating Cells

1995 • 1,058 citations

Requirement for a functional Rb-1 gene in murine development

1992 • 1,015 citations

Myogenin gene disruption results in perinatal lethality because of severe muscle defect

1993 • 912 citations

Cooperative activation of muscle gene expression by MEF2 and myogenic bHLH proteins

1995 • 817 citations

Altered cell differentiation and proliferation in mice lacking p57KIP2 indicates a role in Beckwith–Wiedemann syndrome

1997 • 753 citations

Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiation

1993 • 734 citations

bHLH factors in muscle development: dead lines and commitments, what to leave in and what to leave out.

1994 • 686 citations

Myogenin expression, cell cycle withdrawal, and phenotypic differentiation are temporally separable events that precede cell fusion upon myogenesis.

1996 • 601 citations

Mef2 gene expression marks the cardiac and skeletal muscle lineages during mouse embryogenesis

1994 • 553 citations

Requirement of MADS Domain Transcription Factor D-MEF2 for Muscle Formation in Drosophila

1995 • 502 citations

Ablation of the CDK inhibitor p57Kip2 results in increased apoptosis and delayed differentiation during mouse development.

1997 • 496 citations

Commitment, fusion and biochemical differentiation of a myogenic cell line in the absence of DNA synthesis

1978 • 491 citations

Growth factor control of skeletal muscle differentiation: commitment to terminal differentiation occurs in G1 phase and is repressed by fibroblast growth factor.

1987 • 480 citations

Retinoblastoma protein positively regulates terminal adipocyte differentiation through direct interaction with C/EBPs.

1996 • 446 citations

Drosophila MEF2, a transcription factor that is essential for myogenesis.

1995 • 426 citations

Shared role of the pRB-related p130 and p107 proteins in limb development.

1996 • 424 citations

MyoD-Induced Expression of p21 Inhibits Cyclin-Dependent Kinase Activity upon Myocyte Terminal Differentiation

1995 • 416 citations

Cdk inhibitors in development and cancer

1996 • 410 citations

Inhibition of myogenic differentiation in proliferating myoblasts by cyclin D1-dependent kinase

1995 • 404 citations

Reversal of Terminal Differentiation Mediated by p107 in Rb ^-/- Muscle Cells

1994 • 369 citations

Hoxb-4 (Hox-2.6) mutant mice show homeotic transformation of a cervical vertebra and defects in the closure of the sternal rudiments

1993 • 352 citations

Stable binding to E2F is not required for the retinoblastoma protein to activate transcription, promote differentiation, and suppress tumor cell growth

1998 • 340 citations

The retinoblastoma gene family: cousins with overlapping interests

1998 • 337 citations

MITOSIS AND THE PROCESSES OF DIFFERENTIATION OF MYOGENIC CELLS IN VITRO

1969 • 318 citations

Skeletal muscle cells lacking the retinoblastoma protein display defects in muscle gene expression and accumulate in S and G2 phases of the cell cycle.

1996 • 305 citations

pRb controls proliferation, differentiation, and death of skeletal muscle cells and other lineages during embryogenesis.

1996 • 298 citations

Myogenin is required for late but not early aspects of myogenesis during mouse development.

1995 • 292 citations

Ectopic expression of cyclin D1 prevents activation of gene transcription by myogenic basic helix-loop-helix regulators.

1994 • 186 citations

Cyclin-Mediated Inhibition of Muscle Gene Expression via a Mechanism That Is Independent of pRB Hyperphosphorylation

1996 • 131 citations

Rb binds c-Jun and activates transcription

1998 • 122 citations

Infection of muscle cultures from various species with oncogenic DNA viruses (SV40 and polyoma).

1967 • 79 citations

Homeodomain protein MHox and MADS protein myocyte enhancer-binding factor-2 converge on a common element in the muscle creatine kinase enhancer

1994 • 76 citations

E1A-mediated inhibition of myogenesis correlates with a direct physical interaction of E1A12S and basic helix-loop-helix proteins.

1993 • 56 citations

Ectopic Expression of Cyclin D1 Prevents Activation of Gene Transcription by Myogenic Basic Helix-Loop-Helix Regulators

1994 • 56 citations

The inhibition of cultured myoblast differentiation by the simian virus 40 large T antigen occurs after myogenin expression and Rb up-regulation and is not exerted by transformation-competent cytoplasmic mutants

1995 • 25 citations

The relationship of polyoma virus-induced tumor (T) antigen to activation of DNA synthesis in rat myotubes

1973 • 21 citations

Adenovirus Infection Induces Reentry into the Cell Cycle of Terminally Differentiated Skeletal Muscle Cells^a

1995 • 21 citations

Inhibition of Myogenic Differentiation in Proliferating Myoblasts by Cyclin D1-Dependent Kinase

1995 • 20 citations

E1A-Mediated Inhibition of Myogenesis Correlates with a Direct Physical Interaction of E1A_12S and Basic Helix-Loop-Helix Proteins

1993 • 14 citations

The effect of polyoma virus on differentiating multinucleated muscle fibers.

1967 • 12 citations