Ceramide formation during heat shock: a potential mediator of alpha B-crystallin transcription.

JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

1994 • 3,219 citations

The stress-activated protein kinase subfamily of c-Jun kinases

1994 • 2,616 citations

Alpha-crystallin can function as a molecular chaperone.

1992 • 1,822 citations

Programmed Cell Death Induced by Ceramide

1993 • 1,779 citations

Transcription Factor ATF2 Regulation by the JNK Signal Transduction Pathway

1995 • 1,453 citations

TNF activates NF-κB by phosphatidylcholine-specific phospholipase C-induced “Acidic” sphingomyelin breakdown

1992 • 1,058 citations

Ceramide activates heterotrimeric protein phosphatase 2A

1993 • 657 citations

Sphingomyelin turnover induced by vitamin D3 in HL-60 cells

1989 • 629 citations

Identification of sphingomyelin turnover as an effector mechanism for the action of tumor necrosis factor alpha and gamma-interferon. Specific role in cell differentiation.

1991 • 621 citations

Activation of the Sphingomyelin Cycle Through the Low-Affinity Neurotrophin Receptor

1994 • 583 citations

Alpha B-crystallin is a small heat shock protein.

1991 • 526 citations

Tumor Necrosis Factor-α Activates the Sphingomyelin Signal Transduction Pathway in a Cell-Free System

1992 • 428 citations

Two putative protein-tyrosine kinases identified by application of the polymerase chain reaction.

1989 • 413 citations

Sphingomyelins in bilayers and biological membranes

1980 • 367 citations

Interleukin-1-mediated PGE2 production and sphingomyelin metabolism. Evidence for the regulation of cyclooxygenase gene expression by sphingosine and ceramide.

1992 • 272 citations

Diverse gene sequences are overexpressed in werner syndrome fibroblasts undergoing premature replicative senescence.

1991 • 196 citations

Cell Cycle Arrest Induced by an Inhibitor of Glucosylceramide Synthase

1995 • 165 citations

Expression of the α-Crystallin/Small Heat-Shock Protein/Molecular Chaperone Genes in the Lens and other Tissues

1994 • 152 citations

Alpha-crystallin/small heat shock protein has autokinase activity.

1994 • 138 citations

Ceramide stimulates epidermal growth factor receptor phosphorylation in A431 human epidermoid carcinoma cells. Evidence that ceramide may mediate sphingosine action

1991 • 134 citations

αB-Crystallin Expression in Mouse NIH 3T3 Fibroblasts: Glucocorticoid Responsiveness and Involvement in Thermal Protection

1993 • 126 citations

Analogs of ceramide that inhibit glucocerebroside synthetase in mouse brain

1980 • 123 citations

Coordinate and independent regulation of αB‐crystallin and HSP27 expression in response to physiological stress

1994 • 119 citations

Identification of a defect in the phospholipase D/diacylglycerol pathway in cellular senescence

1994 • 117 citations

Modulation of renal epithelial cell growth by glucosylceramide. Association with protein kinase C, sphingosine, and diacylglycerol.

1991 • 98 citations

Ceramide regulates oxidant release in adherent human neutrophils

1994 • 77 citations

Dissociation of endogenous cellular ceramide from NF-kappa B activation.

1994 • 67 citations

The murine alpha B-crystallin/small heat shock protein enhancer: identification of alpha BE-1, alpha BE-2, alpha BE-3, and MRF control elements.

1993 • 65 citations

Diverse Gene Sequences Are Overexpressed in Werner Syndrome Fibroblasts Undergoing Premature Replicative Senescence

1991 • 46 citations

The Murine αB-Crystallin/Small Heat Shock Protein Enhancer: Identification of αBE-1, αBE-2, αBE-3, and MRF Control Elements

1993 • 15 citations