Quantitative autoradiographic mapping of μ-, δ- and κ-opioid receptors in knockout mice lacking the μ-opioid receptor gene

The Mouse Brain in Stereotaxic Coordinates

2001 • 12,804 citations

Drugs of abuse: anatomy, pharmacology and function of reward pathways

1992 • 2,091 citations

The rat brain in stereotaxic coordinates (2nd edn)

1987 • 1,743 citations

Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the µ-opioid-receptor gene

1996 • 1,652 citations

Autoradiographic differentiation of mu, delta and kappa opioid receptors in the rat forebrain and midbrain

1988 • 980 citations

Pharmacological Mechanisms of Opioid Analgesics

1993 • 559 citations

Neurobiology of opiate abuse

1992 • 546 citations

Opiate receptor knockout mice define μ receptor roles in endogenous nociceptive responses and morphine-induced analgesia

1997 • 511 citations

Deltorphins: a family of naturally occurring peptides with high affinity and selectivity for delta opioid binding sites.

1989 • 453 citations

Multiple opioid receptors: ligand selectivity profiles and binding site signatures.

1989 • 441 citations

Recent advances in molecular recognition and signal transduction of active peptides: Receptors for opioid peptides

1995 • 386 citations

Neuroanatomical patterns of the mu, delta, and kappa opioid receptors of rat brain as determined by quantitative in vitro autoradiography.

1987 • 377 citations

Minireview: Multiple MU opiate receptors

1986 • 348 citations

Kappa opiate receptor multiplicity: evidence for two U50,488-sensitive kappa 1 subtypes and a novel kappa 3 subtype.

1989 • 331 citations

Differential antagonism of delta opioid agonists by naltrindole and its benzofuran analog (NTB) in mice: evidence for delta opioid receptor subtypes.

1991 • 330 citations

κ-Opioid receptors and analgesia

1990 • 318 citations

Differential antagonism of opioid delta antinociception by [D-Ala2,Leu5,Cys6]enkephalin and naltrindole 5'-isothiocyanate: evidence for delta receptor subtypes.

1991 • 265 citations

Discrete mapping of brain mu and delta opioid receptors using selective peptides: Quantitative autoradiography, species differences and comparison with kappa receptors

1989 • 207 citations

δ-Opioid receptor subtypes and cross-talk with μ-receptors

1993 • 188 citations

Altered Hematopoiesis, Behavior, and Sexual Function in μ Opioid Receptor–deficient Mice

1997 • 171 citations

Autoradiographic localization of μ- and δ-opiate receptors in the forebrain of the rat

1986 • 170 citations

CI‐977, a novel and selective agonist for the κ‐opioid receptor

1990 • 150 citations

Mechanisms of the analgesic actions of opiates and opioids

1991 • 148 citations

Delta opioid receptor mRNA distribution in the brain: Comparison to delta receptor binding and proenkephalin mRNA

1993 • 143 citations

Light microscopic autoradiographic localization of mu and delta opioid binding sites in the mouse central nervous system

1984 • 136 citations

Spinal opioid delta antinociception in the mouse: mediation by a 5'-NTII-sensitive delta receptor subtype.

1992 • 118 citations

Autoradiographic distribution of Mu1 and Mu2 opioid binding in the mouse central nervous system

1985 • 117 citations

The kappa-opioid receptor: Evidence for the different subtypes

1993 • 110 citations

Neuroanatomical localization ofκ1and κ2 opioid receptors in rat and guinea pig brain

1991 • 108 citations

Modulation of μ-mediated antinociception by δ agonists in the mouse: selective potentiation of morphine and normorphine by [D-Pen2, D-Pen5]enkephalin

1989 • 99 citations

Modulation of μ-mediated antinociception by δ agonists: characterization with antagonists

1989 • 86 citations

Immunocytochemical localization of delta opioid receptors in mouse brain

1995 • 64 citations

Subtypes of the κ-opioid receptor: fact or fiction?

1989 • 62 citations

Autoradiographic localization in rat brain of κ opiate binding sites labelled by [3Hbremazocine

1986 • 58 citations

Light microscopic autoradiographic localization of delta opioid receptors in the rat brain using a highly selective bis-penicillamine cyclic enkephalin analog.

1986 • 52 citations

Comparative binding of μ and δ selective ligands in whole brain and pons/medulla homogenates from rat: Affinity profiles of fentanyl derivatives

1988 • 51 citations

Quantitative autoradiographic mapping of delta‐opioid receptors in the rat central nervous system using [¹²⁵I][D.Ala²]deltorphin‐I

1993 • 50 citations

Endogenous opiates: 1993

1994 • 49 citations

[125I][D-Ala2]deltorphin-I: A high affinity, delta-selective opioid receptor ligand

1991 • 44 citations

Effects of the δ‐opioid receptor antagonist naltrindole on antinociceptive responses to selective δ‐agonists in post‐weanling rats

1992 • 35 citations

κ3 opiate receptor binding in the mouse and rat

1992 • 33 citations

Development of delta-opioid receptor subtypes and the regulatory role of weaning: radioligand binding, autoradiography and in situ hybridization studies.

1995 • 31 citations

Contribution of supraspinal μ- and δ-opioid receptors to antinociception in the rat

1991 • 30 citations

Fentanyl isothiocyanate reveals the existence of physically associated μ- and δ-opioid receptors mediating inhibition of adenylate cyclase in rat neostriatum

1988 • 26 citations

Autoradiographic study on [3H]-[D-Ala2]-deltorphin-I binding sites in the rat brain.

1993 • 20 citations