Back to search

Acute Consumption of Flavanol-Rich Cocoa and the Reversal of Endothelial Dysfunction in Smokers

Data up to Jan 2025

Published2005
Citations344
References45

Total Citations Per Year

Abstract

References (45)

Atherosclerosis — An Inflammatory Disease

1999 • 21,494 citations

Guidelines for the ultrasound assessment of endothelial-dependent flow-mediated vasodilation of the brachial artery

2002 • 4,535 citations

The pathophysiology of cigarette smoking and cardiovascular disease

2004 • 2,125 citations

Endothelium‐derived relaxing and contracting factors

1989 • 2,017 citations

Nitric Oxide Is Responsible for Flow-Dependent Dilatation of Human Peripheral Conduit Arteries In Vivo

1995 • 1,632 citations

Cigarette smoking is associated with dose-related and potentially reversible impairment of endothelium-dependent dilation in healthy young adults.

1993 • 1,542 citations

The Effect of Fruit and Vegetable Intake on Risk for Coronary Heart Disease

2001 • 1,410 citations

Nitric oxide circulates in mammalian plasma primarily as an S-nitroso adduct of serum albumin.

1992 • 1,237 citations

Nutritional, Dietary and Postprandial Oxidative Stress

2005 • 590 citations

Impaired Progenitor Cell Activity in Age-Related Endothelial Dysfunction

2005 • 563 citations

Short- and Long-Term Black Tea Consumption Reverses Endothelial Dysfunction in Patients With Coronary Artery Disease

2001 • 540 citations

Short-term administration of dark chocolate is followed by a significant increase in insulin sensitivity and a decrease in blood pressure in healthy persons

2005 • 515 citations

Procyanidin dimer B2 [epicatechin-(4β-8)-epicatechin] in human plasma after the consumption of a flavanol-rich cocoa

2002 • 509 citations

Flavanol-rich cocoa induces nitric-oxide-dependent vasodilation in healthy humans

2003 • 496 citations

Flavonoid-Rich Dark Chocolate Improves Endothelial Function and Increases Plasma Epicatechin Concentrations in Healthy Adults

2004 • 467 citations

Tetrahydrobiopterin Improves Endothelium-Dependent Vasodilation in Chronic Smokers

2000 • 448 citations

Red Wine Polyphenols Enhance Endothelial Nitric Oxide Synthase Expression and Subsequent Nitric Oxide Release From Endothelial Cells

2002 • 425 citations

Thrombin Activates the Hypoxia-Inducible Factor-1 Signaling Pathway in Vascular Smooth Muscle Cells

2001 • 415 citations

l-Ascorbic Acid Potentiates Endothelial Nitric Oxide Synthesis via a Chemical Stabilization of Tetrahydrobiopterin

2001 • 410 citations

Uptake and metabolism of epicatechin and its access to the brain after oral ingestion

2002 • 360 citations

Epicatechin in Human Plasma: In Vivo Determination and Effect of Chocolate Consumption on Plasma Oxidation Status

2000 • 359 citations

Intravascular flow decreases erythrocyte consumption of nitric oxide

1999 • 302 citations

Effects of inhaled nitric oxide on regional blood flow are consistent with intravascular nitric oxidedelivery

2001 • 267 citations

Effects of Cocoa Extracts on Endothelium-Dependent Relaxation

2000 • 266 citations

Plasma kinetics in man of epicatechin from black chocolate

1999 • 253 citations

Identification and Characterization of Methylated and Ring-Fission Metabolites of Tea Catechins Formed in Humans, Mice, and Rats

2002 • 250 citations

Smoking a Single Cigarette Rapidly Reduces Combined Concentrations of Nitrate and Nitrite and Concentrations of Antioxidants in Plasma

2002 • 244 citations

Bioavailability of (-)-epicatechin upon intake of chocolate and cocoa in human volunteers

2000 • 237 citations

Reactive Oxygen Species Are Involved in Smoking-Induced Dysfunction of Nitric Oxide Biosynthesis and Upregulation of Endothelial Nitric Oxide Synthase

2003 • 231 citations

Effects of inhaled nitric oxide on regional blood flow are consistent with intravascular nitric oxidedelivery

2001 • 229 citations

Evidence for in vivo transport of bioactive nitric oxide in human plasma

2002 • 226 citations

Concomitant presence of N-nitroso and S-nitroso proteins in human plasma

2002 • 193 citations

Inflammation and Endothelial Function

2005 • 178 citations

Evidence for in vivo transport of bioactive nitric oxide in human plasma

2002 • 177 citations

Plasma Nitrosothiols Contribute to the Systemic Vasodilator Effects of Intravenously Applied NO

2002 • 175 citations

Effects of S-nitroso-glutathione in the human forearm circulation: evidence for selective inhibition of platelet activation

1994 • 166 citations

Biological activity of nitric oxide in the plasmatic compartment

2004 • 162 citations

Bioavailability of Flavan-3-ols and Procyanidins: Gastrointestinal Tract Influences and Their Relevance to Bioactive Forms In Vivo

2001 • 155 citations

Endothelium-dependent vasodilation in the brachial artery is impaired in smokers: effect of vitamin C

1997 • 130 citations

Dark chocolate inhibits platelet aggregation in healthy volunteers

2003 • 98 citations

Red wine's antioxidants counteract acute endothelial dysfunction caused by cigarette smoking in healthy nonsmokers

2004 • 79 citations

<scp>l</scp> -Arginine and S -Nitrosoglutathione Reduce Embolization in Humans

2001 • 78 citations

Uncontrolled Hypertension, Uncompensated Type II Diabetes, and Smoking Have Different Patterns of Vascular Dysfunction

2004 • 67 citations

Automated Ultrasonic Measurement of Human Arteries for the Determination of Endothelial Function

2002 • 57 citations

Rossi, R. et al. Physiological levels of S-nitrosothiols in human plasma. Circ. Res. 89, E47-E47

2002 • 12 citations

Cited By (0)

Loading...