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Intake-dependent Effect of Cocoa Flavanol Absorption, Metabolism and Excretion in Humans

NCT03201822

NAINTERVENTIONAL
University of California, Davis
14 participants
Started 2013-04-01 · Completed 2013-05-25
Status: Completed (as of 12-23-2025)

Conditions

Healthy

Interventions

OTHER: 100 mg of Cocoa Flavanols/70 kg BWOTHER: 200 mg of Cocoa Flavanols/70 kg BWOTHER: 400 mg of Cocoa Flavanols/70 kg BWOTHER: 1000 mg of Cocoa Flavanols/70 kg BW

Linked Papers (from SciSciNet-V2)

Total Papers5
Background
0
Result
0
Derived
0
Unknown
5
View on ClinicalTrials.gov

Total Citations Per Year

Brief Summary

A randomized, double-masked and cross-over dietary intervention study in healthy young adult males to evaluate the concentration of F-derived metabolites in plasma and urine after single acute intakes of F-containing drinks on four different test days.

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Background Papers0

No background papers linked

Result Papers0

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Derived Papers0

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Unknown Papers5

Acute Consumption of Flavanol-Rich Cocoa and the Reversal of Endothelial Dysfunction in Smokers
2005
344 citations
Structurally related (−)-epicatechin metabolites in humans: Assessment using de novo chemically synthesized authentic standards
2011
142 citations
Hypertension, the Kuna, and the Epidemiology of Flavanols
2006
126 citations
Recommending flavanols and procyanidins for cardiovascular health: Current knowledge and future needs
2010
117 citations
Dose-dependent shifts in the sulfation and glucuronidation of phenolic compounds in the rat in vivo and in isolated hepatocytes
1981
95 citations