Similarity of the conformation of diphtheria toxin at high temperature to that in the membrane-penetrating low-pH state.

Stability of Proteins Small Globular Proteins

1979 • 2,139 citations

Fluorescence quenching studies with proteins

1981 • 1,700 citations

Exposure of tryptophanyl residues in proteins. Quantitative determination by fluorescence quenching studies

1976 • 1,020 citations

Diphtheria Toxin

1977 • 780 citations

Membrane fusion proteins of enveloped animal viruses

1983 • 670 citations

Weak bases and ionophores rapidly and reversibly raise the pH of endocytic vesicles in cultured mouse fibroblasts.

1982 • 569 citations

Diphtheria toxin entry into cells is facilitated by low pH.

1980 • 467 citations

Fusion mutants of the influenza virus hemagglutinin glycoprotein

1985 • 399 citations

The entry of diphtheria toxin into the mammalian cell cytoplasm: evidence for lysosomal involvement.

1980 • 372 citations

Diphtheria toxin fragment forms large pores in phospholipid bilayer membranes.

1981 • 341 citations

Nucleotide sequence of the structural gene for diphtheria toxin carried by corynebacteriophage beta.

1983 • 307 citations

Rapid entry of nicked diphtheria toxin into cells at low pH. Characterization of the entry process and effects of low pH on the toxin molecule.

1981 • 291 citations

Diphtheria toxin forms transmembrane channels in planar lipid bilayers.

1981 • 281 citations

Effect of pH on the conformation of diphtheria toxin and its implications for membrane penetration

1985 • 188 citations

pH in the endosome

1984 • 176 citations

Circular differential scattering can be an important part of the circular dichroism of macromolecules.

1983 • 164 citations

Secondary structure and assembly mechanism of an oligomeric channel protein

1985 • 160 citations

Fluorescein conjugates as indicators of subcellular pH

1984 • 144 citations

Binding of triton X-100 to diphtheria toxin, crossreacting material 45, and their fragments.

1976 • 139 citations

Nucleotide Sequence and Expression of the Diphtheria tox 228 Gene in Escherichia coli

1983 • 120 citations

The complete nucleotide sequence of the gene coding for diphtheria toxin in the corynephage omega (tox⁺) genome

1983 • 110 citations

Evidence for direct insertion of fragments A and B of diphtheria toxin into model membranes.

1984 • 87 citations

Evidence for penetration of diphtheria toxin to the cytosol through a prelysosomal membrane

1984 • 80 citations

Mechanism of insertion of diphtheria toxin: peptide entry and pore size determinations.

1984 • 77 citations

Fluorescence characterization of the low pH-induced change in diphtheria toxin conformation: Effect of salt

1984 • 41 citations

An endogenous dinucleotide bound to diphtheria toxin. Adenylyl-(3',5')-uridine 3'-monophosphate.

1981 • 37 citations

Preliminary crystallographic investigation of the protein toxin from corynebacterium diphtheriae.

1982 • 30 citations

Immunotoxins

1984 • 30 citations

Effect of temperature on functional properties of carp hemoglobin

1980 • 24 citations

Diphtheria toxin

1982 • 21 citations

Gating of ion channels made by a diphtheria toxin fragment in phospholipid bilayer membranes.

1983 • 17 citations

Action Spectrum for the Appearance of the 520 mμ Difference Band in Illuminated Chlorella Cells

1964 • 16 citations

Thermal stability of different forms of diphtheria toxin

1984 • 6 citations