Expression cloning of a rat brain somatostatin receptor cDNA.

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

SV40-transformed simian cells support the replication of early SV40 mutants

1981 • 2,564 citations

Transcription termination and 3′ processing: the end is in site!

1985 • 1,482 citations

Synthesis and Processing of Asparagine-Linked Oligosaccharides

1981 • 1,403 citations

At least six nucleotides preceding the AUG initiator codon enhance translation in mammalian cells

1987 • 1,189 citations

Protein kinase recognition sequence motifs

1990 • 1,014 citations

Evolutionary conservation in the untranslated regions of actin mRNAs: DNA sequence of a human beta-actin cDNA

1984 • 973 citations

High level transient expression of a chloramphenicol acetyl transferase gene by DEAE-dextran mediated DNA transfection coupled with a dimethyl sulfoxide or glycerol shock treatment

1984 • 898 citations

cDNA Expression Cloning of the IL-1 Receptor, a Member of the Immunoglobulin Superfamily

1988 • 896 citations

Human IL-3 (multi-CSF): Identification by expression cloning of a novel hematopoietic growth factor related to murine IL-3

1986 • 823 citations

Molecular cloning of a CD28 cDNA by a high-efficiency COS cell expression system.

1987 • 802 citations

Palmitoylation of the human β2-adrenergic receptor

1989 • 599 citations

Somatostatin

1983 • 581 citations

Rhodopsin Mutants That Bind But Fail to Activate Transducin

1990 • 377 citations

Electroporation in biology: Methods, applications, and instrumentation

1988 • 335 citations

The Role of Somatostatin in the Regulation of Anterior Pituitary Hormone Secretion and the Use of Its Analogs in the Treatment of Human Pituitary Tumors

1988 • 271 citations

Somatostatin stimulates Ca2+-activated K+ channels through protein dephosphorylation

1991 • 261 citations

Somatostatin receptors: identification and characterization in rat brain membranes.

1981 • 252 citations

Structure/function relationship of proteins belonging to the family of receptors coupled to GTP‐binding proteins

1991 • 241 citations

Two Types of Somatostatin Receptors Differentiated by Cyclic Somatostatin Analogs

1985 • 228 citations

High affinity binding sites for a somatostatin-28 analog in rat brain

1981 • 192 citations

Evidence for two somatostatin-14 receptor types in rat brain cortex

1984 • 179 citations

Somatostatin-14 and somatostatin-28 induce opposite effects on potassium currents in rat neocortical neurons.

1989 • 145 citations

Identification of the subunits of GTP-binding proteins coupled to somatostatin receptors.

1991 • 144 citations

New specific radioligand for one subpopulation of brain somatostatin receptors

1985 • 141 citations

Optimization of electroporation for transfection of mammalian cell lines

1989 • 111 citations

The somatostatin receptor on isolated pancreatic acinar cell plasma membranes. Identification of subunit structure and direct regulation by cholecystokinin.

1984 • 101 citations

Pertussis Toxin Blocks the Somatostatin-Induced Inhibition of Growth Hormone Release and Adenosine 3′,5′ -Monophosphate Accumulation^*

1983 • 98 citations

Ontogeny of somatostatin receptors in the rat brain: Biochemical and autoradiographic study

1989 • 84 citations

Generation of high efficiency, single-stranded DNA hybridization probes by PCR.

1991 • 65 citations

Characterization of Pituitary Membrane Receptors for Somatostatin in the Rat*

1982 • 65 citations

Somatostatin potentiates the alpha 1-adrenergic activation of phospholipase C in striatal astrocytes through a mechanism involving arachidonic acid and glutamate.

1991 • 57 citations

Different ionic requirements for somatostatin receptor subpopulations in the brain

1986 • 55 citations

Somatostatin receptors in the adrenal

1986 • 53 citations

Functional somatostatin receptors on a rat pancreatic acinar cell line

1988 • 47 citations

Identification and characterization of somatostatin receptors in neonatal rat long bones

1990 • 43 citations

Biochemical properties of brain somatostatin receptors

1989 • 42 citations

Somatostatin receptors on rat cerebrocortical membranes. Structural characterization of somatostatin-14 and somatostatin-28 receptors and comparison with pancreatic type receptors.

1988 • 39 citations

Pertussis toxin modifies the characteristics of both the inhibitory GTP binding proteins and the somatostatin receptor in anterior pituitary tumor cells.

1988 • 37 citations

Pharmacological Characterization of Somatostatin Receptors in the Rat Cerebellum During Development

1990 • 35 citations

Purification of a putative brain somatostatin receptor.

1989 • 35 citations

Somatostatin Receptors in Normal and Tumoral Tissue

1988 • 31 citations

[33] Sib selection

1987 • 30 citations

Solubilization of active somatostatin receptors from rat brain.

1990 • 26 citations

Inhibition of the growth of transplanted rat pancreatic acinar carcinoma with octreotide

1991 • 25 citations

Regional distribution of somatostatin receptor affinity states in rat brain: effects of divalent cations and GTP

1989 • 25 citations

Somatostatin increases intracellular Ca2+ concentration in cultured rat hippocampal neurons

1989 • 19 citations

Generation of high efficiency, single-stranded DNA hybridization probes by PCR.

1991 • 16 citations