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Somatostatin stimulates Ca2+-activated K+ channels through protein dephosphorylation

Data up to Jan 2025

Published1991
Citations261
References38

Total Citations Per Year

Abstract

References (38)

THE STRUCTURE AND REGULATION OF PROTEIN PHOSPHATASES

1989 • 2,518 citations

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1988 • 1,777 citations

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1987 • 393 citations

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1979 • 296 citations

Somatostatin analogues inhibit growth of pancreatic cancer by stimulating tyrosine phosphatase.

1989 • 288 citations

Modulation of single Ca2+-dependent K+-channel activity by protein phosphorylation

1985 • 249 citations

A guanine nucleotide-binding protein mediates the inhibition of voltage-dependent calcium current by somatostatin in a pituitary cell line.

1986 • 243 citations

Calcium channel regulation by calcineurin, a Ca2+-activated phosphatase in mammalian brain

1989 • 195 citations

Pertussis toxin blocks both cyclic AMP-mediated and cyclic AMP-independent actions of somatostatin. Evidence for coupling of Ni to decreases in intracellular free calcium.

1985 • 190 citations

Reconstitution of Somatostatin and Muscarinic Receptor Mediated Stimulation of K+Channels by Isolated GKProtein in Clonal Rat Anterior Pituitary Cell Membranes *

1987 • 188 citations

Cholecystokinin activation of single-channel currents is mediated by internal messenger in pancreatic acinar cells

1982 • 177 citations

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1989 • 162 citations

Ionic currents in two strains of rat anterior pituitary tumor cells.

1984 • 142 citations

The Somatostatin Receptor Is Directly Coupled to Adenylate Cyclase in GH4Ci Pituitary Cell Membranes*

1984 • 130 citations

Characterization of the cyclic AMP-independent actions of somatostatin in GH cells. I. An increase in potassium conductance is responsible for both the hyperpolarization and the decrease in intracellular free calcium produced by somatostatin.

1988 • 122 citations

Somatostatin, an inhibitor of ACTH secretion, decreases cytosolic free calcium and voltage-dependent calcium current in a pituitary cell line

1986 • 110 citations

Somatostatin Inhibits Basal and Vasoactive Intestinal Peptide-Stimulated Hormone Release by Different Mechanisms in GH Pituitary Cells*

1983 • 101 citations

Cyclic AMP-independent, dual regulation of voltage-dependent Ca2+ currents by LHRH and somatostatin in a pituitary cell line.

1988 • 101 citations

Two distinct calcium‐activated potassium currents in a rat anterior pituitary cell line.

1987 • 100 citations

Somatostatin Inhibits Vasoactive Intestinal Peptide-Stimulated Cyclic Adenosine Monophosphate Accumulation in GH Pituitary Cells*

1983 • 93 citations

Hyperpolarization of the membrane potential caused by somatostatin in dissociated human pituitary adenoma cells that secrete growth hormone.

1986 • 89 citations

GTP-dependent regulation of myometrial KCa channels incorporated into lipid bilayers.

1990 • 86 citations

Calcium-dependent inactivation of the dihydropyridine-sensitive calcium channels in GH3 cells.

1988 • 83 citations

Somatostatin lowers the cytosolic free Ca2+ concentration in clonal rat pituitary cells (GH3 cells)

1984 • 81 citations

Pertussis toxin blocks the inhibitory effects of somatostatin on cAMP-dependent vasoactive intestinal peptide and cAMP-independent thyrotropin releasing hormone-stimulated prolactin secretion of GH3 cells.

1986 • 78 citations

Dihydropyridine Ca2+ antagonists: potent inhibitors of secretion from normal and transformed pituitary cells

1985 • 73 citations

Somatostatin Blocks Ca2+Action Potential Activity in Prolactin-Secreting Pituitary Tumor Cells through Coordinate Actions on K+ and Ca2+Conductances*

1988 • 71 citations

Structural and Functional Relationships of Guanosine Triphosphate Binding Proteins

1988 • 69 citations

Characterization of the cyclic AMP-independent actions of somatostatin in GH cells. II. An increase in potassium conductance initiates somatostatin-induced inhibition of prolactin secretion.

1988 • 65 citations

Vasoactive intestinal peptide activates Ca2+ -dependent K+ channels through a cAMP pathway in mouse lacrimal cells

1988 • 58 citations

Differential modulation of Ca2+-activated K+ channels in ovine pituitary gonadotrophs by GnRH, Ca2+ and cyclic AMP

1989 • 35 citations

Requirement of GTP on somatostatin-induced K+ current in human pituitary tumor cells.

1988 • 33 citations

Preface

1990 • 2 citations

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Somatostatin stimulates Ca2+-activated K+ channels through protein dephosphorylation (1991) – Nature | Metascience Observatory Explorer