Cortical dysplasia resembling human type 2 lissencephaly in mice lacking all three APP family members

Epigenetic Regulations of GABAergic Neurotransmission: Relevance for Neurological Disorders and Epigenetic Therapy

2016 • 8,701 citations

Reeler/Disabled-like Disruption of Neuronal Migration in Knockout Mice Lacking the VLDL Receptor and ApoE Receptor 2

1999 • 1,231 citations

Reelin and brain development

2003 • 713 citations

β-amyloid precursor protein-deficient mice show reactive gliosis and decreased locomotor activity

1995 • 686 citations

Role of the Reelin Signaling Pathway in Central Nervous System Development

2001 • 662 citations

Proteolytic processing and cell biological functions of the amyloid precursor protein

2000 • 622 citations

Kinesin-mediated axonal transport of a membrane compartment containing β-secretase and presenilin-1 requires APP

2001 • 581 citations

β1-Class Integrins Regulate the Development of Laminae and Folia in the Cerebral and Cerebellar Cortex

2001 • 555 citations

Interaction of Cytosolic Adaptor Proteins with Neuronal Apolipoprotein E Receptors and the Amyloid Precursor Protein

1998 • 544 citations

Mice with Combined Gene Knock-Outs Reveal Essential and Partially Redundant Functions of Amyloid Precursor Protein Family Members

2000 • 485 citations

Expression of a ubiquitous, cross-reactive homologue of the mouse beta-amyloid precursor protein (APP).

1994 • 349 citations

Neuronal migration disorders: from genetic diseases to developmental mechanisms

2000 • 340 citations

Generation of APLP2 KO Mice and Early Postnatal Lethality in APLP2/APP Double KO Mice

1997 • 327 citations

Behavioral and anatomical deficits in mice homozygous for a modified ?-amyloid precursor protein gene

1994 • 307 citations

Dissection of Amyloid-β Precursor Protein-dependent Transcriptional Transactivation

2004 • 307 citations

Essential role of α6 integrins in cortical and retinal lamination

1998 • 301 citations

MARCKS deficiency in mice leads to abnormal brain development and perinatal death.

1995 • 291 citations

Distinct Intramembrane Cleavage of the β-Amyloid Precursor Protein Family Resembling γ-Secretase-like Cleavage of Notch

2001 • 289 citations

The beta-amyloid precursor protein of Alzheimer's disease enhances neuron viability and modulates neuronal polarity.

1997 • 250 citations

Silver Impregnation of Reticulum in Paraffin Sections.

1937 • 244 citations

The Alzheimer Amyloid Precursor Protein (APP) and Fe65, an APP-Binding Protein, Regulate Cell Movement

2001 • 239 citations

The Alzheimer's Disease Amyloid Precursor Protein Modulates Copper-Induced Toxicity and Oxidative Stress in Primary Neuronal Cultures

1999 • 222 citations

Cleavage of Amyloid-β Precursor Protein and Amyloid-β Precursor-like Protein by BACE 1

2004 • 216 citations

The Proteolytic Processing of the Amyloid Precursor Protein Gene Family Members APLP-1 and APLP-2 Involves α-, β-, γ-, and ϵ-Like Cleavages

2004 • 206 citations

Disabled-1 Binds to the Cytoplasmic Domain of Amyloid Precursor-Like Protein 1

1999 • 188 citations

The β-Amyloid Precursor Protein of Alzheimer’s Disease Enhances Neuron Viability and Modulates Neuronal Polarity

1997 • 187 citations

Rescue of Ataxia and Preplate Splitting by Ectopic Expression of Reelin in reeler Mice

2002 • 183 citations

beta-Amyloid precursor protein binds to the neurite-promoting IKVAV site of laminin.

1993 • 180 citations

Defective glycosylation in muscular dystrophy

2002 • 171 citations

Regulation of Amyloid Protein Precursor (APP) Binding to Collagen and Mapping of the Binding Sites on APP and Collagen Type I

1996 • 170 citations

Genetic background changes the pattern of forebrain commissure defects in transgenic mice underexpressing the β-amyloid-precursor protein

1999 • 169 citations

Expression in mouse embryos and in adult mouse brain of three members of the amyloid precursor protein family, of the alpha-2-macroglobulin receptor/low density lipoprotein receptor-related protein and of its ligands apolipoprotein E, lipoprotein lipase, alpha-2-macroglobulin and the 40,000 molecular weight receptor-associated protein

1995 • 166 citations

Generation of mice with a 200-kb amyloid precursor protein gene deletion by Cre recombinase-mediated site-specific recombination in embryonic stem cells.

1996 • 145 citations

Potential Link between Amyloid β-Protein 42 and C-terminal Fragment γ 49–99 of β-Amyloid Precursor Protein

2003 • 141 citations

Defective glycosylation in congenital muscular dystrophies

2004 • 140 citations

Processing of β-Amyloid Precursor-like Protein-1 and -2 by γ-Secretase Regulates Transcription

2002 • 139 citations

Presenilin-1 deficiency leads to loss of Cajal–Retzius neurons and cortical dysplasia similar to human type 2 lissencephaly

1999 • 136 citations

Cell surface amyloid beta-protein precursor colocalizes with beta 1 integrins at substrate contact sites in neural cells.

1997 • 132 citations

Functions of brain chondroitin sulfate proteoglycans during developments: interactions with adhesion molecules.

1996 • 116 citations

Hypersensitivity to seizures in β-amyloid precursor protein deficient mice

1998 • 112 citations

γ-Secretase Cleavage and Binding to FE65 Regulate the Nuclear Translocation of the Intracellular C-Terminal Domain (ICD) of the APP Family of Proteins

2003 • 101 citations

Cell Surface Amyloid β-Protein Precursor Colocalizes with β1 Integrins at Substrate Contact Sites in Neural Cells

1997 • 95 citations

Survival of cultured neurons from amyloid precursor protein knock-out mice against Alzheimer's amyloid-beta toxicity and oxidative stress.

1998 • 90 citations

The β‐Amyloid Precursor Protein (APP) and Alzheimer's Disease: Does the Tail Wag the Dog?

2002 • 82 citations

Alzheimer's disease amyloid precursor protein on the surface of cortical neurons in primary culture co-localizes with adhesion patch components

1996 • 81 citations

Identification of Heparin‐Binding Domains in the Amyloid Precursor Protein of Alzheimer's Disease by Deletion Mutagenesis and Peptide Mapping

1997 • 80 citations

Neurobehavioral development, adult openfield exploration and swimming navigation learning in mice with a modified β-amyloid precursor protein gene

1998 • 75 citations

Survival of Cultured Neurons from Amyloid Precursor Protein Knock-Out Mice against Alzheimer’s Amyloid-β Toxicity and Oxidative Stress

1998 • 73 citations

Widespread Neuronal Ectopia Associated with Secondary Defects in Cerebrocortical Chondroitin Sulfate Proteoglycans and Basal Lamina in MARCKS-Deficient Mice

1997 • 57 citations

Loss ofEmx2function leads to ectopic expression ofWnt1in the developing telencephalon and cortical dysplasia

2003 • 56 citations

Neuronal Migration Defects in the Dreher (Lmx1a) Mutant Mouse: Role of Disorders of the Glial Limiting Membrane

2001 • 34 citations

Some morphometric methods for the central nervous system

1975 • 26 citations