Vitamin D compounds and diabetic nephropathy

Clinical epidemiology of cardiovascular disease in chronic renal disease

1998 • 3,896 citations

Endocrine Regulation of Energy Metabolism by the Skeleton

2007 • 2,443 citations

FGF-23 Is a Potent Regulator of Vitamin D Metabolism and Phosphate Homeostasis

2004 • 1,745 citations

Diabetic Nephropathy: Diagnosis, Prevention, and Treatment

2005 • 1,717 citations

Prevalence of abnormal serum vitamin D, PTH, calcium, and phosphorus in patients with chronic kidney disease: Results of the study to evaluate early kidney disease

2006 • 1,440 citations

An Endocytic Pathway Essential for Renal Uptake and Activation of the Steroid 25-(OH) Vitamin D3

1999 • 989 citations

Survival of Patients Undergoing Hemodialysis with Paricalcitol or Calcitriol Therapy

2003 • 930 citations

Fibroblast Growth Factor-23 Mitigates Hyperphosphatemia but Accentuates Calcitriol Deficiency in Chronic Kidney Disease

2005 • 903 citations

Activated Injectable Vitamin D and Hemodialysis Survival

2005 • 780 citations

Selective vitamin D receptor activation with paricalcitol for reduction of albuminuria in patients with type 2 diabetes (VITAL study): a randomised controlled trial

2010 • 672 citations

Proteinuria, albuminuria, risk, assessment, detection, elimination (PARADE): A position paper of the National Kidney Foundation

1999 • 591 citations

Smad3 as a mediator of the fibrotic response

2004 • 577 citations

Expression of Advanced Glycation End Products and Their Cellular Receptor RAGE in Diabetic Nephropathy and Nondiabetic Renal Disease

2000 • 468 citations

Mouse Models of Diabetic Nephropathy

2004 • 452 citations

Vitamin D levels and patient outcome in chronic kidney disease

2008 • 428 citations

Prevalence of Calcidiol Deficiency in CKD: A Cross-Sectional Study Across Latitudes in the United States

2005 • 396 citations

Mortality risk among hemodialysis patients receiving different vitamin D analogs

2006 • 391 citations

Antiproteinuric effect of oral paricalcitol in chronic kidney disease

2005 • 371 citations

Wnt/β-Catenin Signaling Promotes Podocyte Dysfunction and Albuminuria

2009 • 371 citations

Identification of a Vitamin D response element in the human insulin receptor gene promoter

2003 • 364 citations

The Multifunctional Properties and Characteristics of Vitamin D-binding Protein

2000 • 360 citations

Paricalcitol Reduces Albuminuria and Inflammation in Chronic Kidney Disease

2008 • 324 citations

Possible involvement of circulating fibroblast growth factor 23 in the development of secondary hyperparathyroidism associated with renal insufficiency

2004 • 318 citations

Fibroblast growth factor 23 impairs phosphorus and vitamin D metabolism in vivo and suppresses 25-hydroxyvitamin D-1α-hydroxylase expression in vitro

2007 • 289 citations

25-Hydroxyvitamin D Levels and Albuminuria in the Third National Health and Nutrition Examination Survey (NHANES III)

2007 • 288 citations

Combination therapy with AT1 blocker and vitamin D analog markedly ameliorates diabetic nephropathy: Blockade of compensatory renin increase

2008 • 285 citations

Paricalcitol Attenuates Renal Interstitial Fibrosis in Obstructive Nephropathy

2006 • 283 citations

Blockade of Wnt/β-Catenin Signaling by Paricalcitol Ameliorates Proteinuria and Kidney Injury

2010 • 252 citations

Effect of 1,25(OH)2 vitamin D3 on glomerulosclerosis in subtotally nephrectomized rats

1998 • 248 citations

Paricalcitol Inhibits Renal Inflammation by Promoting Vitamin D Receptor–Mediated Sequestration of NF-κB Signaling

2008 • 247 citations

Mechanisms of progression of chronic kidney disease

2007 • 243 citations

Serum levels of 1,25-dihydroxyvitamin D, 24,25-dihydroxyvitamin D, and 25-hydroxyvitamin D in nondialyzed patients with chronic renal failure

1999 • 234 citations

Is the Vitamin D Receptor Found in Muscle?

2010 • 226 citations

1,25-Dihydroxyvitamin D₃decreases podocyte loss and podocyte hypertrophy in the subtotally nephrectomized rat

2004 • 221 citations

Mouse models of diabetic nephropathy

2011 • 199 citations

Oral Paricalcitol in the Treatment of Patients With CKD and Proteinuria: A Randomized Trial

2009 • 188 citations

Parathyroid hormone inhibits 25-hydroxyvitamin D3-24-hydroxylase mRNA expression stimulated by 1 alpha,25-dihydroxyvitamin D3 in rat kidney but not in intestine.

1992 • 186 citations

Vitamin D and Kidney Disease

2008 • 173 citations

Hypovitaminosis D in Chronic Kidney Disease

2008 • 170 citations

1,25-Dihydroxyvitamin D3 targeting of NF-κB suppresses high glucose-induced MCP-1 expression in mesangial cells

2007 • 169 citations

Enhanced Excretion of Vitamin D Binding Protein in Type 1 Diabetes: A Role in Vitamin D Deficiency?

2010 • 136 citations

Reduction of the vitamin D hormonal system in kidney disease is associated with increased renal inflammation

2008 • 132 citations

Oral cholecalciferol decreases albuminuria and urinary TGF-β1 in patients with type 2 diabetic nephropathy on established renin–angiotensin–aldosterone system inhibition

2011 • 129 citations

Direct Renin Inhibition with Aliskiren in Hypertension and Target Organ Damage

2005 • 129 citations

Defective Photoproduction of Cholecalciferol in Normal and Uremic Humans

1984 • 116 citations

Possible renoprotection by vitamin D in chronic renal disease: beyond mineral metabolism

2009 • 112 citations

Secondary hyperparathyroidism in chronic renal failure: Pathogenic and clinical aspects

2001 • 111 citations

Dysregulation of renal vitamin D metabolism in the uremic rat

2010 • 109 citations

Microalbuminuria in Type 1 Diabetes Is Associated With Enhanced Excretion of the Endocytic Multiligand Receptors Megalin and Cubilin

2009 • 106 citations

Free and total 1,25-dihydroxyvitamin D levels in subjects with renal disease

1992 • 103 citations

1,25-dihydroxyvitamin D3 inhibits renal interstitial myofibroblast activation by inducing hepatocyte growth factor expression

2005 • 102 citations

Functional Cooperation between CCAAT/Enhancer-Binding Proteins and the Vitamin D Receptor in Regulation of 25-Hydroxyvitamin D₃ 24-Hydroxylase

2004 • 101 citations

Persistent Renal Hypertrophy and Faster Decline of Glomerular Filtration Rate Precede the Development of Microalbuminuria in Type 1 Diabetes

2006 • 97 citations

Oral Calcitriol for the Treatment of Persistent Proteinuria in Immunoglobulin A Nephropathy: An Uncontrolled Trial

2008 • 93 citations

2-Methylene-19-nor-(20S)-1,25-dihydroxyvitamin D3 Potently Stimulates Gene-specific DNA Binding of the Vitamin D Receptor in Osteoblasts

2003 • 90 citations

Vitamin D Analogs Modulate the Expression of Plasminogen Activator Inhibitor-1, Thrombospondin-1 and Thrombomodulin in Human Aortic Smooth Muscle Cells

2006 • 86 citations

Vitamin D receptor agonist doxercalciferol modulates dietary fat-induced renal disease and renal lipid metabolism

2011 • 82 citations

22-Oxacalcitriol prevents progressive glomerulosclerosis without adversely affecting calcium and phosphorus metabolism in subtotally nephrectomized rats

2002 • 79 citations

Nephropathy of type 1 and type 2 diabetes: diverse pathophysiology, same treatment?

2000 • 77 citations

CYP24A1 and kidney disease

2011 • 77 citations

Vitamin D metabolism in the kidney: Regulation by phosphorus and fibroblast growth factor 23

2011 • 67 citations

1,25-(OH2)D3 Alters the Transforming Growth Factor β Signaling Pathway in Renal Tissue

2001 • 66 citations

Regulation of the Porcine 1,25-Dihydroxyvitamin D3-24-Hydroxylase (CYP24) by 1,25-Dihydroxyvitamin D3 and Parathyroid Hormone in AOK-B50 Cells

2000 • 65 citations

Antiproteinuric treatment reduces urinary loss of vitamin D-binding protein but does not affect vitamin D status in patients with chronic kidney disease

2011 • 61 citations

The Functional Metabolism and Molecular Biology of Vitamin D Action

2009 • 58 citations

Therapeutic Modalities in Diabetic Nephropathy: Standard and Emerging Approaches

2011 • 56 citations

Podocytes as Target of Vitamin D

2011 • 53 citations

Vitamin D and glucose metabolism in chronic kidney disease

2008 • 49 citations

Renal Lesions in Spontaneous Insulin-dependent Diabetes Mellitus in the Nonobese Diabetic Mouse: Acute Phase of Diabetes

2003 • 40 citations

Contributions of nuclear architecture and chromatin to vitamin D-dependent transcriptional control of the rat osteocalcin gene

2001 • 38 citations

Modulatory role of 1,25 dihydroxyvitamin D₃ on pancreatic islet insulin release via the cyclic AMP pathway in the rat

1997 • 35 citations

Effect of Combination Therapy with Angiotensin Receptor Blocker and 1,25-Dihydroxyvitamin D<sub>3</sub> in Type 2 Diabetic Nephropathy in KK-A<sup>y</sup>/Ta Mice

2010 • 34 citations

The nature of vitamin D resistance of patients with chronic renal disease.

1969 • 32 citations

Renal 25-hydroxyvitamin D3-1-hydroxylase in patients with renal disease

1988 • 26 citations

The Nature of Vitamin D Resistance of Patients With Chronic Renal Disease

1969 • 23 citations

Vitamin D and diabetic nephropathy

2008 • 23 citations

Intensive Glycemic Control and Renal Outcome

2011 • 22 citations

THE ROLE OF PARICALCITOL ON PROTEINURIA

2011 • 19 citations

The vitamin D system: a view from basic science to the clinic

1981 • 14 citations

2α-Methyl-19-nor-(20S)-1,25-dihydroxyvitamin D3 protects the insulin 2 knockout non-obese diabetic mouse from developing type 1 diabetes without hypercalcaemia

2011 • 11 citations

Interactions between renal tubules and interstitium.

1996 • 9 citations

Changes of renal vitamin D metabolic enzyme expression and calcium transporter abundance in obstructive nephropathy

2011 • 6 citations

Vitamin D3-24-hydroxylase (CYP24) as a potential target for intervention with diabetic and nondiabetic nephropathy.

2007 • 3 citations