Endogenous bone morphogenetic protein antagonists regulate mammalian neural crest generation and survival

Mitosis-specific phosphorylation of histone H3 initiates primarily within pericentromeric heterochromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensation

1997 • 1,814 citations

Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse.

1995 • 1,782 citations

Fate of the mammalian cranial neural crest during tooth and mandibular morphogenesis

2000 • 1,400 citations

Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase

1998 • 1,272 citations

Dorsal differentiation of neural plate cells induced by BMP-mediated signals from epidermal ectoderm

1995 • 1,060 citations

Neural Crest and the Origin of Vertebrates: A New Head

1983 • 1,011 citations

Identification of BMP-4 as a signal mediating secondary induction between epithelial and mesenchymal tissues during early tooth development

1993 • 908 citations

Noggin-mediated antagonism of BMP signaling is required for growth and patterning of the neural tube and somite

1998 • 838 citations

Noggin, Cartilage Morphogenesis, and Joint Formation in the Mammalian Skeleton

1998 • 810 citations

Alternative Neural Crest Cell Fates Are Instructively Promoted by TGFβ Superfamily Members

1996 • 785 citations

Sox10, a Novel Transcriptional Modulator in Glial Cells

1998 • 759 citations

Bmp4 and Morphological Variation of Beaks in Darwin's Finches

2004 • 745 citations

Tissue Origins and Interactions in the Mammalian Skull Vault

2002 • 734 citations

Bone morphogenetic proteins (BMPs) as regulators of dorsal forebrain development

1997 • 705 citations

DORSAL-VENTRAL PATTERNING AND NEURAL INDUCTION IN XENOPUS EMBRYOS

2004 • 652 citations

Transcription factor AP-2 essential for cranial closure and craniofacial development

1996 • 611 citations

Extracellular Regulation of BMP Signaling in Vertebrates: A Cocktail of Modulators

2002 • 602 citations

Neural tube, skeletal and body wall defects in mice lacking transcription factor AP-2

1996 • 595 citations

Transcription factor AP-2 is expressed in neural crest cell lineages during mouse embryogenesis.

1991 • 593 citations

The organizer factors Chordin and Noggin are required for mouse forebrain development

2000 • 528 citations

Ectodermal Wnt Function as a Neural Crest Inducer

2002 • 507 citations

The signalling molecule BMP4 mediates apoptosis in the rhombencephalic neural crest

1994 • 486 citations

Neural crest induction in Xenopus: evidence for a two-signal model

1998 • 472 citations

Vital dye analysis of cranial neural crest cell migration in the mouse embryo

1992 • 470 citations

Failure of Bone Marrow Cells to Transdifferentiate into Neural Cells in Vivo

2002 • 451 citations

Fgf8is required for pharyngeal arch and cardiovascular development in the mouse

2002 • 446 citations

Gene-Regulatory Interactions in Neural Crest Evolution and Development

2004 • 439 citations

Ventral and Lateral Regions of the Zebrafish Gastrula, Including the Neural Crest Progenitors, Are Established by abmp2b/swirlPathway of Genes

1998 • 424 citations

A new family of mouse homeo box-containing genes: molecular structure, chromosomal location, and developmental expression of Hox-7.1.

1989 • 399 citations

Induction of the neural crest: a multigene process

2002 • 344 citations

Early embryonic lethality in Bmp5;Bmp7 double mutant mice suggests functional redundancy within the 60A subgroup

1999 • 343 citations

Patterning the cranial neural crest: Hinbrain segmentation and hox gene plasticity

2000 • 338 citations

Xenopus msx1 mediates epidermal induction and neural inhibition by BMP4

1997 • 311 citations

Pathways of trunk neural crest cell migration in the mouse embryo as revealed by vital dye labelling

1990 • 300 citations

Regulation of Msx genes by a Bmp gradient is essential for neural crest specification

2003 • 296 citations

Inhibition of Sonic hedgehog signaling in vivo results in craniofacial neural crest cell death

1999 • 289 citations

Haploinsufficient Phenotypes inBmp4Heterozygous Null Mice and Modification by Mutations inGli3andAlx4

1997 • 282 citations

The Cellular and Molecular Origins of Beak Morphology

2003 • 275 citations

The inductive properties of mesoderm suggest that the neural crest cells are specified by a BMP gradient

1998 • 270 citations

Regulation of the onset of neural crest migration by coordinated activity of BMP4 and Noggin in the dorsal neural tube

1999 • 254 citations

A role for rhoB in the delamination of neural crest cells from the dorsal neural tube

1998 • 244 citations

Gap Junction–mediated Cell–Cell Communication Modulates Mouse Neural Crest Migration

1998 • 242 citations

Molecular Shaping of the Beak

2004 • 241 citations

Establishment and maintenance of the border of the neural plate in the chick: involvement of FGF and BMP activity

1999 • 236 citations

Sox10 is required for the early development of the prospective neural crest in Xenopus embryos

2003 • 228 citations

Differential Regulation ofchordinExpression Domains in Mutant Zebrafish

1997 • 210 citations

Dorsal and intermediate neuronal cell types of the spinal cord are established by a BMP signaling pathway

2000 • 208 citations

Neural crest formation in the head of the mouse embryo as observed using a new histological technique

1981 • 201 citations

Analysis of Spatial and Temporal Gene Expression Patterns in Blastula and Gastrula Stage Chick Embryos

2002 • 198 citations

Chordin and noggin promote organizing centers of forebrain development in the mouse

2002 • 198 citations

Induction of neural crest in Xenopus by transcription factor AP2α

2003 • 186 citations

Cadherin-6 Expression Transiently Delineates Specific Rhombomeres, Other Neural Tube Subdivisions, and Neural Crest Subpopulations in Mouse Embryos

1997 • 185 citations

BMP signaling is essential for development of skeletogenic and neurogenic cranial neural crest

2000 • 182 citations

BMP receptor IA is required in mammalian neural crest cells for development of the cardiac outflow tract and ventricular myocardium

2004 • 180 citations

Molecular control of neural crest formation, migration and differentiation

2000 • 175 citations

The role of chordin/Bmp signals in mammalian pharyngeal development and DiGeorge syndrome

2003 • 170 citations

In vivo convergence of BMP and MAPK signaling pathways: impact of differential Smad1 phosphorylation on development and homeostasis

2004 • 162 citations

Early induction of neural crest cells: lessons learned from frog, fish and chick

2002 • 160 citations

Wnt1-Cre-mediated deletion of AP-2α causes multiple neural crest-related defects

2003 • 153 citations

Isolation of Sna, a mouse gene homologous to the Drosophila genes snail and escargot: its expression pattern suggests multiple roles during postimplantation development

1992 • 144 citations

The BMP Antagonists Chordin and Noggin Have Essential but Redundant Roles in Mouse Mandibular Outgrowth

2001 • 133 citations

Effects of Shh and Noggin on neural crest formation demonstrate that BMP is required in the neural tube but not ectoderm

1998 • 131 citations

Regulative capacity of the cranial neural tube to form neural crest

1993 • 125 citations

Distinct activities of Msx1 and Msx3 in dorsal neural tube development

2004 • 124 citations

Formation and distribution of neural crest mesenchyme to the first pharyngeal arch region of the mouse embryo

1986 • 124 citations

Mouse cellular retinoic acid binding protein: cloning, complementary DNA sequence, and messenger RNA expression during the retinoic acid-induced differentiation of F9 wild type and RA-3-10 mutant teratocarcinoma cells.

1989 • 122 citations

Environmental signals and cell fate specification in premigratory neural crest

2000 • 110 citations

BMP-7 influences pattern and growth of the developing hindbrain of mouse embryos

1997 • 108 citations

Neural Induction and Patterning in the Mouse in the Absence of the Node and Its Derivatives

1999 • 107 citations

Cephalic Neural Crest and Placodes

1979 • 105 citations

Delayed neural crest cell emigration from Sp and Sp^d mouse neural tube explants

1990 • 79 citations

Modulation of BMP Activity in Dorsal-Ventral Pattern Formation by the Chordin and Ogon Antagonists

2002 • 56 citations

Spatiotemporal expression patterns of mammalian chordin during postgastrulation embryogenesis and in postnatal brain

2000 • 53 citations

Restricting Bmp-4 mediated apoptosis in hindbrain neural crest

2001 • 49 citations

Requirement of Xmsx-1 in the BMP-triggered ventralization of Xenopus embryos

2000 • 45 citations

Aortic arch and pharyngeal phenotype in the absence of BMP-dependent neural crest in the mouse

2002 • 43 citations

Cell-intrinsic and cell-extrinsic cues regulating lineage decisions in multipotent neural crest-derived progenitor cells.

2002 • 42 citations

Changes in Homeobox-Containing Gene Expression during Ectopic Bone Formation Induced by Bone Morphogenetic Protein

1994 • 33 citations

Introduction

1979 • 30 citations

Cyclopamine, a steroidal alkaloid, disrupts development of cranial neural crest cells in Xenopus

1995 • 26 citations

Cited By (0)

Loading...