Establishment and maintenance of the border of the neural plate in the chick: involvement of FGF and BMP activity

A series of normal stages in the development of the chick embryo

1951 • 12,226 citations

The Spemann Organizer Signal noggin Binds and Inactivates Bone Morphogenetic Protein 4

1996 • 1,604 citations

Dorsal differentiation of neural plate cells induced by BMP-mediated signals from epidermal ectoderm

1995 • 1,060 citations

Retinoic acid causes an anteroposterior transformation in the developing central nervous system

1989 • 885 citations

Induction of epidermis and inhibition of neural fate by Bmp-4

1995 • 782 citations

Follistatin, an antagonist of activin, is expressed in the Spemann organizer and displays direct neuralizing activity

1994 • 759 citations

Cerberus is a head-inducing secreted factor expressed in the anterior endoderm of Spemann's organizer

1996 • 757 citations

Regulation of neural induction by the Chd and Bmp-4 antagonistic patterning signals in Xenopus

1995 • 731 citations

A positive feedback loop coordinates growth and patterning in the vertebrate limb

1994 • 702 citations

A role for bone morphogenetic proteins in the induction of cardiac myogenesis.

1997 • 687 citations

Fgf-4 expression during gastrulation, myogenesis, limb and tooth development in the mouse

1992 • 676 citations

The Xenopus Dorsalizing Factor Gremlin Identifies a Novel Family of Secreted Proteins that Antagonize BMP Activities

1998 • 649 citations

Anterior primitive endoderm may be responsible for patterning the anterior neural plate in the mouse embryo

1996 • 548 citations

A truncated activin receptor inhibits mesoderm induction and formation of axial structures in Xenopus embryos

1992 • 538 citations

A New Technique for the Cultivation of the Chick Embryo in vitro

1955 • 530 citations

Segment-specific expression of a zinc-finger gene in the developing nervous system of the mouse

1989 • 511 citations

A comparison of the properties ofSox-3withSryand two related genes,Sox-1andSox-2

1996 • 485 citations

Inhibition of activin receptor signaling promotes neuralization in Xenopus

1994 • 484 citations

Neural crest induction in Xenopus: evidence for a two-signal model

1998 • 472 citations

Ectodermal Patterning in Vertebrate Embryos

1997 • 457 citations

Induction of the prospective neural crest of Xenopus

1995 • 451 citations

Origins of the avian neural crest: the role of neural plate-epidermal interactions

1995 • 423 citations

On the function of BMP-4 in patterning the marginal zone of the Xenopus embryo.

1994 • 396 citations

Fibroblast growth factor is a direct neural inducer, which combined with noggin generates anterior-posterior neural pattern

1995 • 390 citations

Embryonic expression of the chicken Sox2, Sox3 and Sox11 genes suggests an interactive role in neuronal development

1995 • 388 citations

FGFs and BMP4 induce both Msx1-independent and Msx1-dependent signaling pathways in early tooth development

1998 • 371 citations

Disruption of BMP signals in embryonic Xenopus ectoderm leads to direct neural induction.

1995 • 368 citations

Secreted noggin protein mimics the Spemann organizer in dorsalizing Xenopus mesoderm

1993 • 365 citations

Identification of a retinoic acid-sensitive period during primary axis formation in Xenopus laevis.

1990 • 364 citations

Concentration-dependent patterning of the Xenopus ectoderm by BMP4 and its signal transducer Smad1

1997 • 354 citations

Chordin regulates primitive streak development and the stability of induced neural cells, but is not sufficient for neural induction in the chick embryo

1998 • 350 citations

Ventral mesodermal patterning in Xenopus embryos: Expression patterns and activities of BMP‐2 and BMP‐4

1995 • 344 citations

Activation and organization of the central nervous system in amphibians. Part I. Induction and activation

1952 • 319 citations

Xenopus msx1 mediates epidermal induction and neural inhibition by BMP4

1997 • 311 citations

A role for FGF-8 in the initiation and maintenance of vertebrate limb bud outgrowth

1995 • 303 citations

Dorsalization of the neural tube by the non-neural ectoderm

1995 • 295 citations

Expression of a novel FGF in theXenopusembryo. A new candidate inducing factor for mesoderm formation and anteroposterior specification

1992 • 291 citations

Caudalization of neural fate by tissue recombination and bFGF

1995 • 290 citations

The inductive properties of mesoderm suggest that the neural crest cells are specified by a BMP gradient

1998 • 270 citations

Neural induction and regionalisation in the chick embryo

1992 • 250 citations

Endoderm induction by the organizer-secreted factors chordin and noggin in Xenopus animal caps.

1996 • 248 citations

A spinal cord fate map in the avian embryo: while regressing, Hensen’s node lays down the notochord and floor plate thus joining the spinal cord lateral walls

1996 • 233 citations

Dynamic expression of chicken Sox2 and Sox3 genes in ectoderm induced to form neural tissue

1997 • 226 citations

Wnt and FGF pathways cooperatively pattern anteroposterior neural ectoderm in Xenopus

1997 • 224 citations

Specification of the Anteroposterior Neural Axis through Synergistic Interaction of the Wnt Signaling Cascade withnogginandfollistatin

1995 • 222 citations

Retinoic acid modifies the pattern of cell differentiation in the central nervous system of neurula stage Xenopus embryos

1991 • 204 citations

Organization and development of the tail bud analyzed with the quail-chick chimaera system

1995 • 203 citations

A truncated FGF receptor blocks neural induction by endogenous Xenopus inducers

1996 • 198 citations

c-otx2 is expressed in two different phases of gastrulation and is sensitive to retinoic acid treatment in chick embryo

1995 • 197 citations

The origins of neural crest cells in the axolotl

1990 • 187 citations

Mesodermal subdivision along the mediolateral axis in chicken controlled by different concentrations of BMP-4

1997 • 183 citations

Role of FGF andNogginin Neural Crest Induction

1997 • 183 citations

The Drosophila short gastrulation gene prevents Dpp from autoactivating and suppressing neurogenesis in the neuroectoderm.

1996 • 178 citations

Multiple roles for FGF-3 during cranial neural development in the chicken

1995 • 176 citations

Neural Crest Induction by Xwnt7B in Xenopus

1998 • 175 citations

Expression of Pax-3 is initiated in the early neural plate by posteriorizing signals produced by the organizer and by posterior non-axial mesoderm

1997 • 172 citations

A graded response to BMP-4 spatially coordinates patterning of the mesoderm and ectoderm in the zebrafish

1997 • 168 citations

Preventing the loss of competence for neural induction: HGF/SF, L5 and Sox-2

1997 • 162 citations

Early posterior neural tissue is induced by FGF in the chick embryo

1998 • 160 citations

Direct neural induction and selective inhibition of mesoderm and epidermis inducers by Xnr3

1997 • 158 citations

Msx2 Is a Transcriptional Regulator in the BMP4-Mediated Programmed Cell Death Pathway

1997 • 153 citations

Cwnt-8C: a novel Wnt gene with a potential role in primitive streak formation and hindbrain organization

1993 • 153 citations

Locations of the ectodermal and nonectodermal subdivisions of the epiblast at stages 3 and 4 of avian gastrulation and neurulation

1993 • 146 citations

The origins of the neural crest. Part I: embryonic induction

1997 • 144 citations

THE CULTIVATION OF TISSUES IN SALINE EMBRYONIC JUICE.

1924 • 143 citations

Über Induktion von Medullarplatte durch Medullarplatte im Jüngeren Keim, ein Beispiel homöogenetischer oder assimilatorischer Induktion

1927 • 138 citations

Developmental expression of the Xenopus int-2 (FGF-3) gene: activation by mesodermal and neural induction

1992 • 136 citations

An integrated experimental study of endoderm formation in avian embryos

1981 • 136 citations

Vertebrate Neural Induction: Inducers, Inhibitors, and a New Synthesis

1997 • 131 citations

A Dominant Negative Bone Morphogenetic Protein 4 Receptor Causes Neuralization in Xenopus Ectoderm

1995 • 127 citations

13 Detection of Multiple Gene Products Simultaneously by in situ Hybridization and lmmunohistochemistry in Whole Mounts of Avian Embryos

1997 • 124 citations

Paraxial-Fated Mesoderm Is Required for Neural Crest Induction inXenopusEmbryos

1998 • 121 citations

A role for HGF/SF in neural induction and its expression in Hensen’s node during gastrulation

1995 • 106 citations

Formation of ectopic neurepithelium in chick blastoderms: Age‐related capacities for induction and self‐differentiation following transplantation of quail Hensen's nodes

1990 • 101 citations

A role for BMP-4 in the development of subcutaneous cartilage

1996 • 97 citations

The role in neural patterning of translation initiation factor eIF4AII; induction of neural fold genes

1997 • 93 citations

Neural Activation and Transformation in Explants of Competent Ectoderm under the Influence of Fragments of Anterior Notochord in Urodeles

1954 • 92 citations

Neural Induction in Whole Chick Embryo Cultures by FGF

1998 • 85 citations

Chick noggin is expressed in the organizer and neural plate during axial development, but offers no evidence of involvement in primary axis formation.

1997 • 82 citations

Continuing organizer function during chick tail development

1998 • 76 citations

Mesoderm patterning and somite formation during node regression: differential effects of chordin and noggin

1999 • 75 citations

cash4, a novel achaete-scute homolog induced by Hensen's node during generation of the posterior nervous system.

1997 • 71 citations

Nucleo-cytoplasmic translocation and secretion of fibroblast growth factor-2 during avian gastrulation

1995 • 66 citations

Quantitative analyses of cell behaviors underlying notochord formation and extension in mouse embryos

1994 • 54 citations

Cloning, sequencing, and expressional analysis of the chick homologue of follistatin

1995 • 53 citations

The inducing capacities of the primary hypoblast as revealed by transfilter induction studies

1970 • 46 citations

Formation of ectopic neuroepithelium in chick blastoderms: age related capacities for induction and selfdifferentiating following transplantation of quail Hensen's node

1990 • 45 citations

State of Commitment of Prospective Neural Plate and Prospective Mesoderm in Late Gastrula/Early Neurula Stages of Avian Embryos

1997 • 42 citations

The roles of activin and follistatin signaling in chick gastrulation.

1998 • 36 citations

Spatial and temporal relationships betweenShh, Fgf4, andFgf8 gene expression at diverse signalling centers during mouse development

1996 • 36 citations

8 Embryonic Explant and Slice Preparations for Studies of Cell Migration and Axon Guidance

1997 • 32 citations

Studies on the Role of Fibroblast Growth Factor Signaling in Neurogenesis Using Conjugated/Aged Animal Caps and Dorsal Ectoderm-Grafted Embryos

1997 • 28 citations

Origin of the avian neural crestt

1995 • 16 citations

Neural Induction by Previously Induced Epiblast in Avian Embryo in vitro

1976 • 8 citations