Molecular properties of the proteasome activator PA28 family proteins and γ‐interferon regulation

STRUCTURE AND FUNCTIONS OF THE 20S AND 26S PROTEASOMES

1996 • 2,408 citations

The ubiquitin-proteasome proteolytic pathway

1994 • 1,778 citations

UBIQUITIN-DEPENDENT PROTEIN DEGRADATION

1996 • 1,680 citations

THE UBIQUITIN SYSTEM FOR PROTEIN DEGRADATION

1992 • 1,402 citations

ANTIGEN PROCESSING AND PRESENTATION BY THE CLASS I MAJOR HISTOCOMPATIBILITY COMPLEX

1996 • 613 citations

γ-Interferon and expression of MHC genes regulate peptide hydrolysis by proteasomes

1993 • 572 citations

MHC-linked LMP gene products specifically alter peptidase activities of the proteasome

1993 • 453 citations

Identification, purification, and characterization of a protein activator (PA28) of the 20 S proteasome (macropain).

1992 • 439 citations

GENERATION, TRANSLOCATION, AND PRESENTATION OF MHC CLASS I-RESTRICTED PEPTIDES

1995 • 428 citations

Proteasomes: multicatalytic proteinase complexes

1993 • 395 citations

Purification of an 11 S regulator of the multicatalytic protease.

1992 • 384 citations

Proteasomes: destruction as a programme

1996 • 373 citations

Interferon-γ Induces Different Subunit Organizations and Functional Diversity of Proteasomes1

1994 • 371 citations

Proteasomes: protein degradation machines of the cell

1994 • 320 citations

Interferon gamma stimulation modulates the proteolytic activity and cleavage site preference of 20S mouse proteasomes.

1994 • 314 citations

Coordinated Dual Cleavages Induced by the Proteasome Regulator PA28 Lead to Dominant MHC Ligands

1996 • 287 citations

Proteasomes (multi-protease complexes) as 20 S ring-shaped particles in a variety of eukaryotic cells.

1988 • 225 citations

Displacement of housekeeping proteasome subunits by MHC-encoded LMPs: a newly discovered mechanism for modulating the multicatalytic proteinase complex.

1994 • 220 citations

Chronic active hepatitis in transgenic mice expressing interferon-gamma in the liver.

1994 • 217 citations

Primary structures of two homologous subunits of PA28, a γ‐interferon‐inducible protein activator of the 20S proteasome

1995 • 196 citations

Newly identified pair of proteasomal subunits regulated reciprocally by interferon gamma.

1996 • 195 citations

Fluorescence in situ hybridization with Alu and L1 polymerase chain reaction probes for rapid characterization of human chromosomes in hybrid cell lines.

1990 • 186 citations

PA28 Activator Protein Forms Regulatory Caps on Proteasome Stacked Rings

1994 • 167 citations

Proteasome components with reciprocal expression to that of the MHC-encoded LMP proteins

1994 • 157 citations

ATP‐dependent reversible association of proteasomes with multiple protein components to form 26S complexes that degrade ubiquitinated proteins in human HL‐60 cells

1991 • 141 citations

Possible mechanism of nuclear translocation of proteasomes

1990 • 132 citations

Molecular Characterization of the "26S" Proteasome Complex from Rat Liver

1993 • 131 citations

Demonstration that a human 26S proteolytic complex consists of a proteasome and multiple associated protein components and hydrolyzes ATP and ubiquitin‐ligated proteins by closely linked mechanisms

1992 • 115 citations

THE GENETICS OF PROTEASOMES AND ANTIGEN PROCESSING

1995 • 108 citations

Structural Features of 26S and 20S Proteasomes

1993 • 107 citations

Proteasomes and Antigen Processing

1997 • 106 citations

Characterization of the Proteasome Regulator PA28

1996 • 93 citations

Cloning and nucleotide sequence of cDNA for Ki antigen, a highly conserved nuclear protein detected with sera from patients with systemic lupus erythematosus

1990 • 86 citations

Effects of interferon gamma and major histocompatibility complex-encoded subunits on peptidase activities of human multicatalytic proteases.

1995 • 80 citations

A Model for the Quaternary Structure of the Proteasome Activator PA28

1996 • 76 citations

Interferon‐γ up‐regulates a unique set of proteins in human keratinocytes

1993 • 55 citations

Regulatory Proteins of the Proteasome

1993 • 47 citations

cDNA Cloning of p40, a Regulatory Subunit of the Human 26S Proteasome, and a Homolog of the Mov-34 Gene Product

1995 • 28 citations