SINEs and LINEs cluster in distinct DNA fragments of Giemsa band size

CpG-rich islands and the function of DNA methylation

1986 • 3,760 citations

Separation of yeast chromosome-sized DNAs by pulsed field gradient gel electrophoresis

1984 • 2,847 citations

A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomeres of human chromosomes.

1988 • 2,281 citations

Separation of Large DNA Molecules by Contour-Clamped Homogeneous Electric Fields

1986 • 1,525 citations

Fluorescence in situ hybridization with human chromosome-specific libraries: detection of trisomy 21 and translocations of chromosome 4.

1988 • 1,334 citations

Delineation of individual human chromosomes in metaphase and interphase cells by in situ suppression hybridization using recombinant DNA libraries

1988 • 1,171 citations

NONVIRAL RETROPOSONS: GENES, PSEUDOGENES, AND TRANSPOSABLE ELEMENTS GENERATED BY THE REVERSE FLOW OF GENETIC INFORMATION

1986 • 1,032 citations

Ubiquitous, interspersed repeated sequences in mammalian genomes.

1980 • 568 citations

Detection of chromosome aberrations in metaphase and interphase tumor cells by in situ hybridization using chromosome-specific library probes

1988 • 563 citations

Human genome organization: Alu, LINES, and the molecular structure of metaphase chromosome bands

1988 • 563 citations

Replication Timing of Genes and Middle Repetitive Sequences

1984 • 561 citations

THE ROLE OF THE NUCLEAR MATRIX IN THE ORGANIZATION AND FUNCTION OF DNA

1986 • 360 citations

Partial nucleotide sequence of the 300-nucleotide interspersed repeated human DNA sequences

1980 • 346 citations

Cloning defined regions of the human genome by microdissection of banded chromosomes and enzymatic amplification

1989 • 337 citations

The sequence of a large L1Md element reveals a tandemly repeated 5' end and several features found in retrotransposons.

1986 • 326 citations

Unit-length line-1 transcripts in human teratocarcinoma cells.

1988 • 296 citations

Reproducible compartmentalization of individual chromosome domains in human CNS cells revealed by in situ hybridization and three-dimensional reconstruction

1988 • 279 citations

Sequence definition and organization of a human repeated DNA

1980 • 230 citations

L1 family of repetitive DNA sequences in primates may be derived from a sequence encoding a reverse transcriptase-related protein

1986 • 218 citations

Identification and cloning of endogenous retroviral sequences present in human DNA.

1981 • 215 citations

Mid-prophase human chromosomes. The attainment of 2000 bands

1981 • 198 citations

The distribution of interspersed repetitive DNA sequences in the human genome

1989 • 192 citations

Structure of the major block of alphoid satellite DNA on the human Y chromosome

1987 • 163 citations

Making sense out of LINES: long interspersed repeat sequences in mammalian genomes

1985 • 162 citations

Construction and use of human chromosome jumping libraries from NotI-digested DNA

1987 • 145 citations

Chromosomal and nuclear distribution of the HindIII 1.9-kb human DNA repeat segment

1984 • 143 citations

The Sequence of a Large L1Md Element Reveals a Tandemly Repeated 5′ End and Several Features Found in Retrotransposons

1986 • 140 citations

A unified model of eukaryotic chromosomes

1990 • 110 citations

Integration site preferences of the Alu family and similar repetitive DNA sequences

1985 • 106 citations

Transcription of the KpnI families of long interspersed DNAs in human cells

1983 • 87 citations

Nucleotide sequence definition of a major human repeated DNA, the Hind III 1.9 kb family

1982 • 83 citations

Chromosomes and chromatin

1988 • 83 citations

The coordinate replication of the human beta-globin gene domain reflects its transcriptional activity and nuclease hypersensitivity.

1988 • 74 citations

Toward a molecular paleontology of primate genomes

1981 • 68 citations

Temporal Order of Gene Replication in Chinese Hamster Ovary Cells

1989 • 63 citations

Detection of bromodeoxyuridine-incorporation in mammalian chromosomes by a bromodeoxyuridine-antibody

1986 • 61 citations

A novel cDNA/PCR strategy for efficient cloning of small amounts of undefined RNA

1989 • 61 citations

Characterization of human endogenous retroviral envelope RNA transcripts

1985 • 56 citations

Replication of a plasmid bearing a human Alu-family repeat in monkey COS-7 cells.

1986 • 55 citations

Some KpnI family members are associated with the Alu family in the human genome

1983 • 49 citations

Genomic representation of the Hind II 1.9 kb repeated DNA

1982 • 47 citations

Target sites for the transposition of rat long interspersed repeated DNA elements (LINEs) are not random

1986 • 45 citations

Isolation and characterization of cloned human DNA fragments carrying reiterated sequences common to both autosomes and the X chromosome

1981 • 45 citations

Heterochromatin and the Phenomenon of Chromosome Banding

1987 • 43 citations

Toward a molecular paleontology of primate genomes

1981 • 43 citations

Replication time of interspersed repetitive DNA sequences in hamsters

1986 • 40 citations

Temporal order of gene replication in Chinese hamster ovary cells.

1989 • 32 citations

The Coordinate Replication of the Human β-Globin Gene Domain Reflects Its Transcriptional Activity and Nuclease Hypersensitivity

1988 • 23 citations

Transcripts homologous to a long repeated DNA element in the human genome.

1984 • 22 citations

Conservation in the 5' region of the long interspersed mouse L1 repeat: implications of comparative sequence analysis

1986 • 20 citations

Chromatin loop structure of the human X chromosome: relevance to X inactivation and CpG clusters.

1989 • 20 citations

The association of the interspersed repetitive KpnI sequences with the nuclear matrix.

1985 • 18 citations

Human metallothionein-II processed gene is located in region p11→q21 of chromosome 4

1985 • 13 citations

Neuroblastoma double minutes isolated by pulsed-field gel electrophoresis without prior strand-cleaving treatments

1989 • 12 citations

Chromatin Loop Structure of the Human X Chromosome: Relevance to X Inactivation and CpG Clusters

1989 • 6 citations

A Modest Proposal for European Patents

1989 • 5 citations