Detection of chromosome aberrations in metaphase and interphase tumor cells by in situ hybridization using chromosome-specific library probes

Cytogenetic analysis using quantitative, high-sensitivity, fluorescence hybridization.

1986 • 3,231 citations

Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin

1985 • 1,523 citations

Delineation of individual human chromosomes in metaphase and interphase cells by in situ suppression hybridization using recombinant DNA libraries

1988 • 1,171 citations

Zur Frage der Entstehung maligner Tumoren

1914 • 796 citations

GENETICS OF HUMAN CANCER

1986 • 565 citations

Cytogenetic features of human neuroblastomas and cell lines.

1981 • 386 citations

Detection of chromosome aberrations in the human interphase nucleus by visualization of specific target DNAs with radioactive and non-radioactive in situ hybridization techniques: diagnosis of trisomy 18 with probe L1.84

1986 • 380 citations

Zur Frage der Entstehung maligner Tumoren

1914 • 294 citations

Reproducible compartmentalization of individual chromosome domains in human CNS cells revealed by in situ hybridization and three-dimensional reconstruction

1988 • 279 citations

Individual interphase chromosome domains revealed by in situ hybridization

1985 • 274 citations

Genomic Organization of Alpha Satellite DNA on Human Chromosome 7: Evidence for Two Distinct Alphoid Domains on a Single Chromosome

1987 • 231 citations

Specific staining of human chromosomes in Chinese hamster x man hybrid cell lines demonstrates interphase chromosome territories

1985 • 231 citations

Report of the committee on structural chromosome changes in neoplasia

1988 • 230 citations

Amplification of the structurally and functionally altered epidermal growth factor receptor gene (c-erbB) in human brain tumors.

1988 • 218 citations

Gene Amplification in Malignant Human Gliomas: Clinical and Histopathologic Aspects

1988 • 216 citations

2-Acetylaminofluorene-modified probes for the indirect hybridocytochemical detection of specific nucleic acid sequences

1984 • 208 citations

Genetics of cancer predisposition.

1987 • 199 citations

Chromosome 1 aberrations in cancer

1986 • 197 citations

Rapid interphase and metaphase assessment of specific chromosomal changes in neuroectodermal tumor cells by in situ hybridization with chemically modified DNA probes

1988 • 177 citations

Structure and localization of genes encoding aberrant and normal epidermal growth factor receptor RNAs from A431 human carcinoma cells.

1985 • 171 citations

Sensitive system for visualising biotinylated DNA probes hybridised in situ: rapid sex determination of intact cells.

1985 • 168 citations

Genomic organization of alpha satellite DNA on human chromosome 7: evidence for two distinct alphoid domains on a single chromosome.

1987 • 149 citations

Chromosomal evolution in malignant human gliomas starts with specific and usually numerical deviations

1986 • 139 citations

Relationship between gene amplification and chromosomal deviations in malignant human gliomas

1987 • 129 citations

Cytogenetic studies of human brain tumors and their clinical significance. II. Meningioma

1987 • 98 citations

Fluorescence in situ hybridization to interphase cell nuclei in suspension allows flow cytometric analysis of chromosome content and microscopic analysis of nuclear organization

1988 • 95 citations

Somatic cell fusion as a source of genetic rearrangement leading to metastatic variants

1984 • 85 citations

Sex chromosome positions in human interphase nuclei as studied by in situ hybridization with chromosome specific DNA probes

1984 • 83 citations

Polysomy of chromosome 7 is correlated with overexpression of the erbB oncogene in human glioblastoma cell lines

1986 • 80 citations

The Role of Chromosomal Translocations in B- and T-Cell Neoplasia

1987 • 76 citations

Biology of gliomas: heterogeneity, oncogenes, growth factors.

1986 • 74 citations

Isolation and characterization of an ?-satellite repeated sequence from human chromosome 22

1986 • 64 citations

Cytogenetic studies of human brain tumors and their clinical significance

1987 • 60 citations

Report of the committee on structural chromosome changes in neoplasia

1987 • 55 citations

Amplification of the Structurally and Functionally Altered Epidermal Growth Factor Receptor Gene (c-erbB) in Human Brain Tumors

1988 • 53 citations

The Genetic Analysis of Malignancy

1986 • 53 citations

Progress in Neuropathology. Vol. 2

1973 • 49 citations

Catalogue of Chromosome Aberrations in Cancer

1984 • 42 citations

Structure and Localization of Genes Encoding Aberrant and Normal Epidermal Growth Factor Receptor RNAs from A431 Human Carcinoma Cells

1985 • 41 citations

On trisomy of chromosome 7 in human gliomas

1987 • 28 citations