Function of Domains of Human O⁶-Alkylguanine-DNA Alkyltransferase

REGULATION AND EXPRESSION OF THE ADAPTIVE RESPONSE TO ALKYLATING AGENTS

1988 • 645 citations

Active and alkylated human AGT structures: a novel zinc site, inhibitor and extrahelical base binding

2000 • 219 citations

Crystal structure of a suicidal DNA repair protein: the Ada O6-methylguanine-DNA methyltransferase from E. coli.

1994 • 198 citations

Increased spontaneous mutation and alkylation sensitivity of Escherichia coli strains lacking the ogt O6-methylguanine DNA repair methyltransferase

1991 • 187 citations

p53 is involved in regulation of the DNA repair gene O6-methylguanine-DNA methyltransferase (MGMT) by DNA damaging agents

1998 • 138 citations

Hyperthermostable Protein Structure Maintained by Intra and Inter-helix Ion-pairs in Archaeal O6-Methylguanine-DNA Methyltransferase

1999 • 96 citations

DNA-binding Mechanism ofO 6-Alkylguanine-DNA Alkyltransferase

2003 • 75 citations

DNA-repair methyltransferase as a molecular device for preventing mutation and cancer

1996 • 53 citations

O 6-Alkylguanine-DNA Alkyltransferase

2010 • 52 citations

Regulation of expression of the ada gene controlling the adaptive response

1989 • 51 citations

Positive and negative regulation of transcription by a cleavage product of Ada protein

1990 • 45 citations

Roles of DNA repair methyltransferase in mutagenesis and carcinogenesis

1997 • 17 citations