Calcineurin-Mediated LTD of GABAergic Inhibition Underlies the Increased Excitability of CA1 Neurons Associated with LTP

A synaptic model of memory: long-term potentiation in the hippocampus

1993 • 11,303 citations

Long‐lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path

1973 • 7,118 citations

THE STRUCTURE AND REGULATION OF PROTEIN PHOSPHATASES

1989 • 2,518 citations

Long‐lasting potentiation of synaptic transmission in the dentate area of the unanaesthetized rabbit following stimulation of the perforant path

1973 • 1,140 citations

Involvement of a calcineurin/ inhibitor-1 phosphatase cascade in hippocampal long-term depression

1994 • 1,063 citations

Contrasting properties of two forms of long-term potentiation in the hippocampus

1995 • 839 citations

Postsynaptic Calcium Is Sufficient for Potentiation of Hippocampal Synaptic Transmission

1988 • 830 citations

Mice Lacking Metabotropic Glutamate Receptor 5 Show Impaired Learning and Reduced CA1 Long-Term Potentiation (LTP) But Normal CA3 LTP

1997 • 631 citations

Long-term potentiation in the hippocampus is blocked by tyrosine kinase inhibitors

1991 • 520 citations

Activation of NMDA receptors blocks GABAergic inhibition in an in vitro model of epilepsy

1987 • 375 citations

Possible mechanisms for long‐lasting potentiation of synaptic transmission in hippocampal slices from guinea‐pigs.

1980 • 367 citations

Restricted and Regulated Overexpression Reveals Calcineurin as a Key Component in the Transition from Short-Term to Long-Term Memory

1998 • 365 citations

Genetic and Pharmacological Evidence for a Novel, Intermediate Phase of Long-Term Potentiation Suppressed by Calcineurin

1998 • 355 citations

Src Activation in the Induction of Long-Term Potentiation in CA1 Hippocampal Neurons

1998 • 329 citations

Low-frequency stimulation erases LTP through an NMDA receptor-mediated activation of protein phosphatases.

1994 • 281 citations

Associative long-term potentiation in hippocampal slices.

1983 • 280 citations

Inhibitors of protein kinases and phosphatases

1994 • 268 citations

Identification of an autoinhibitory domain in calcineurin.

1990 • 268 citations

Temporal limits on the rise in postsynaptic calcium required for the induction of long-term potentiation

1992 • 258 citations

Long-term potentiation : from biophysics to behavior

1988 • 222 citations

The Return of the Spike

1999 • 193 citations

Long‐term potentiation involves enhanced synaptic excitation relative to synaptic inhibition in guinea‐pig hippocampus.

1987 • 167 citations

Mechanisms of long-term potentiation: EPSP/spike dissociation, intradendritic recordings, and glutamate sensitivity

1988 • 156 citations

Shaping of IPSCs by Endogenous Calcineurin Activity

1997 • 148 citations

Suppression of GABAA receptor responses by NMDA application in hippocampal neurones acutely isolated from the adult guinea‐pig.

1995 • 138 citations

Localization of sodium channels in cultured neural cells

1981 • 135 citations

Spontaneous inhibitory post-synaptic potentials in hippocampus: Mechanism for tonic inhibition

1980 • 134 citations

Facilitatory transmitters and cAMP can modulate accommodation as well as transmitter release in Aplysia sensory neurons: Evidence for parallel processing in a single cell

1986 • 119 citations

Long-term potentiation in thin hippocampal sections studied by intracellular and extracellular recordings

1978 • 118 citations

The EPSP-spike (E-S) component of long-term potentiation in the rat hippocampal slice is modulated by GABAergic but not cholinergic mechanisms

1989 • 114 citations

Heterosynaptic changes accompany long‐term but not short‐term potentiation of the perforant path in the anaesthetized rat.

1985 • 112 citations

A decrease in firing threshold observed after induction of the EPSP-spike (E-S) component of long-term potentiation in rat hippocampal slices

1990 • 111 citations

A role for protein kinases and phosphatases in the Ca2+-induced enhancement of hippocampal AMPA receptor-mediated synaptic responses

1994 • 106 citations

Field potential evidence for long-term potentiation of feed-forward inhibition in the rat dentate gyrus

1987 • 76 citations

Associative EPSP‐‐spike potentiation induced by pairing orthodromic and antidromic stimulation in rat hippocampal slices.

1995 • 70 citations

Thresholds of action potentials evoked by synapses on the dendrites of pyramidal cells in the rat hippocampus in vitro.

1987 • 63 citations

Long‐term potentiation of excitatory synaptic transmission in the rat hippocampus: the role of inhibitory processes

1982 • 59 citations

Calcineurin inhibitors, FK506 and cyclosporin A, suppress the NMDA receptor-mediated potentials and LTP, but not depotentiation in the rat hippocampus

1996 • 57 citations

LTP-associated EPSP/spike dissociation in the dentate gyrus: GABAergic and non-GABAergic components

1991 • 50 citations

Voltage-clamp analysis of synaptic inhibition during long-term potentiation in hippocampus

1986 • 43 citations

Action potential propagation and threshold parameters in inhomogeneous regions of squid axons.

1983 • 42 citations

Only ‘de novo’ long-term depression (LTD) in the rat hippocampus in vitro is blocked by the same low concentration of FK506 that blocks LTD in the visual cortex

1995 • 35 citations

Long-Term Potentiation

1987 • 35 citations

Fast pre-potential generation in rat hippocampal ca1 pyramidal neurons

1993 • 26 citations

Comparison of membrane properties of the cell body and the initial part of the axon of phasic motoneurones in the spinal cord of the cat

1974 • 21 citations

Synaptically triggered action potentials begin as a depolarizing ramp in rat hippocampal neurones in vitro.

1992 • 19 citations