Only ‘de novo’ long-term depression (LTD) in the rat hippocampus in vitro is blocked by the same low concentration of FK506 that blocks LTD in the visual cortex

Inhibition of Postsynaptic PKC or CaMKII Blocks Induction But Not Expression of LTP

1989 • 1,335 citations

Long-Term Depression

1989 • 1,151 citations

A mechanism for the Hebb and the anti-Hebb processes underlying learning and memory.

1989 • 1,114 citations

Mechanisms underlying induction of homosynaptic long-term depression in area CA1 of the hippocampus

1992 • 1,088 citations

Involvement of a calcineurin/ inhibitor-1 phosphatase cascade in hippocampal long-term depression

1994 • 1,063 citations

Whole cell recording from neurons in slices of reptilian and mammalian cerebral cortex

1989 • 977 citations

Different voltage-dependent thresholds for inducing long-term depression and long-term potentiation in slices of rat visual cortex

1990 • 893 citations

Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A.

1992 • 811 citations

Long-term depression of excitatory synaptic transmission and its relationship to long-term potentiation

1993 • 780 citations

An Essential Role for Protein Phosphatases in Hippocampal Long-Term Depression

1993 • 678 citations

Regulation of NMDA receptors by tyrosine kinases and phosphatases

1994 • 671 citations

Mechanisms Underlying Long-Term Potentiation of Synaptic Transmission

1991 • 615 citations

Heterosynaptic depression: a postsynaptic correlate of long-term potentiation

1977 • 606 citations

Bidirectional long-term modification of synaptic effectiveness in the adult and immature hippocampus

1993 • 590 citations

Inhibition of T cell signaling by immunophilin-ligand complexes correlates with loss of calcineurin phosphatase activity

1992 • 561 citations

Persistent protein kinase activity underlying long-term potentiation

1988 • 557 citations

Immunosuppressant FK506 enhances phosphorylation of nitric oxide synthase and protects against glutamate neurotoxicity.

1993 • 543 citations

Modulation of ION Channels by Protein Phosphorylation and Dephosphorylation

1994 • 530 citations

The CaM kinase II hypothesis for the storage of synaptic memory

1994 • 510 citations

Enhancement of the Glutamate Response by cAMP-Dependent Protein Kinase in Hippocampal Neurons

1991 • 486 citations

Regulation of NMDA channel function by endogenous Ca2+-dependent phosphatase

1994 • 483 citations

Long‐term potentiation and depression of synaptic responses in the rat hippocampus: localization and frequency dependency.

1978 • 470 citations

Associative long-term depression in the hippocampus induced by hebbian covariance

1989 • 470 citations

Regulation of neurotransmitter receptor desensitization by protein phosphorylation

1990 • 439 citations

Role of guanylyl cyclase and cGMP-dependent protein kinase in long-term potentiation

1994 • 428 citations

Long‐term Potentiation in the Striatum is Unmasked by Removing the Voltage‐dependent Magnesium Block of NMDA Receptor Channels

1992 • 408 citations

Regulation of Kainate Receptors by cAMP-Dependent Protein Kinase and Phosphatases

1991 • 404 citations

Reversal of long-term potentiation (depotentiation) induced by tetanus stimulation of the input to CA1 neurons of guinea pig hippocampal slices

1991 • 356 citations

Protein kinase C modulation of NMDA currents: an important link for LTP induction

1992 • 350 citations

High brain densities of the immunophilin FKBP colocalized with calcineurin

1992 • 340 citations

The effects of repetitive low frequency stimulation on control and “potentiated” synaptic responses in the hippocampus

1980 • 315 citations

Stable depression of potentiated synaptic responses in the hippocampus with 1–5 Hz stimulation

1990 • 303 citations

GABAA receptor function is regulated by phosphorylation in acutely dissociated guinea‐pig hippocampal neurones.

1990 • 302 citations

Homosynaptic long-term depression in the visual cortex

1994 • 285 citations

The role of protein kinase C in long-term potentiation: a testable model

1989 • 278 citations

Phosphorylation of amino acid neurotransmitter receptors in synaptic plasticity

1993 • 260 citations

Regulation of NMDA receptors in cultured hippocampal neurons by protein phosphatases 1 and 2A

1994 • 210 citations

Excitatory Amino Acids and Neuronal Plasticity

1990 • 121 citations

An inhibitor for calcineurin, FK506, blocks induction of long-term depression in rat visual cortex

1995 • 78 citations

Long-term depression: not so depressing after all.

1993 • 58 citations

Homosynaptic long-term depression in area CA1 of hippocampus and effects of N-methyl-D-aspartate receptor blockade

1995 • 50 citations

Glutamate-stimulated protein phosphorylation in cultured hippocampal pyramidal neurons

1991 • 48 citations

Protein kinase C and long-term potentiation in the hippocampus

1989 • 48 citations

Arachidonic acid and diacylglycerol act synergistically through protein kinase C to persistently enhance synaptic transmission in the hippocampus

1994 • 41 citations

Effects of an inhibitor for calcium/calmodulin-dependent protein phosphatase, calcineurin, on induction of long-term potentiation in rat visual cortex

1994 • 39 citations

FKBP12-FK506 Complex Inhibits Phosphatase Activity of Two Mammalian Isoforms of Calcineurin Irrespective of Their Substrates or Activation Mechanisms11

1993 • 38 citations

Detection of the FK506-FKBP-Calcineurin Complex by a Simple Binding Assay

1993 • 27 citations

The Role of Protein Kinase C Substrate B-50 (GAP-43) in Neurotransmitter Release and Long-Term Potentiation

1990 • 13 citations