Genetic and Pharmacological Evidence for a Novel, Intermediate Phase of Long-Term Potentiation Suppressed by Calcineurin

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Short-Term Synaptic Plasticity

1989 • 1,464 citations

Genetic Demonstration of a Role for PKA in the Late Phase of LTP and in Hippocampus-Based Long-Term Memory

1997 • 1,228 citations

Effects of cAMP Simulate a Late Stage of LTP in Hippocampal CA1 Neurons

1993 • 1,212 citations

CREB Phosphorylation and Dephosphorylation: A Ca2+- and Stimulus Duration–Dependent Switch for Hippocampal Gene Expression

1996 • 1,109 citations

Involvement of a calcineurin/ inhibitor-1 phosphatase cascade in hippocampal long-term depression

1994 • 1,063 citations

Induction of a dominant negative CREB transgene specifically blocks long-term memory in Drosophila

1994 • 959 citations

FK-506- and CsA-sensitive activation of the interleukin-2 promoter by calcineurin

1992 • 865 citations

CREB as a Memory Modulator: induced expression of a dCREB2 activator isoform enhances long-term memory in drosophila

1995 • 639 citations

Long-Term Depression in Hippocampus

1996 • 583 citations

Aplysia CREB2 represses long-term facilitation: Relief of repression converts transient facilitation into long-term functional and structural change

1995 • 575 citations

MAP Kinase Translocates into the Nucleus of the Presynaptic Cell and Is Required for Long-Term Facilitation in Aplysia

1997 • 548 citations

The CaM kinase II hypothesis for the storage of synaptic memory

1994 • 510 citations

Synaptic Desensitization of NMDA Receptors by Calcineurin

1995 • 404 citations

Restricted and Regulated Overexpression Reveals Calcineurin as a Key Component in the Transition from Short-Term to Long-Term Memory

1998 • 365 citations

A generic intron increases gene expression in transgenic mice.

1991 • 351 citations

Blockade of long-term potentiation in rat hippocampal CA1 region by inhibitors of protein synthesis

1984 • 346 citations

Postsynaptic CAMP pathway gates early LTP in hippocampal CA1 region

1995 • 326 citations

Somatic Mutations in Paroxysmal Nocturnal Hemoglobinuria: A Blessing in Disguise?

1997 • 305 citations

Activity-Dependent β-Adrenergic Modulation of Low Frequency Stimulation Induced LTP in the Hippocampal CA1 Region

1996 • 282 citations

β-Adrenergic Regulation of Synaptic NMDA Receptors by cAMP-Dependent Protein Kinase

1996 • 280 citations

Calcineurin regulation of synaptic function: from ion channels to transmitter release and gene transcription

1997 • 239 citations

Recruitment of New Sites of Synaptic Transmission During the cAMP-Dependent Late Phase of LTP at CA3–CA1 Synapses in the Hippocampus

1997 • 225 citations

Long-lasting forms of synaptic potentiation in the mammalian hippocampus.

1996 • 222 citations

Protein synthesis-dependent formation of protein kinase Mzeta in long- term potentiation

1996 • 179 citations

Concerted regulation of protein phosphorylation and dephosphorylation by calmodulin

1991 • 155 citations

[22] Isolation and characterization of bovine brain calcineurin: A calmodulin-stimulated protein phosphatase

1983 • 133 citations

Distinct Cellular Expression of Calcineurin Aα and Aβ in Rat Brain

1992 • 127 citations

Control of rat GluR6 glutamate receptor open probability by protein kinase A and calcineurin

1997 • 119 citations

A biochemist's view of long-term potentiation.

1996 • 117 citations

The balance between postsynaptic Ca(2+)-dependent protein kinase and phosphatase activities controlling synaptic strength.

1996 • 113 citations

Postsynaptic Calcineurin Activity Downregulates Synaptic Transmission by Weakening Intracellular Ca²⁺Signaling Mechanisms in Hippocampal CA1 Neurons

1997 • 111 citations

Control of a Novel Adenylyl Cyclase by Calcineurin

1995 • 98 citations

Involvement of the Ca2+-dependent Phosphatase Calcineurin in Gene Transcription That Is Stimulated by cAMP through cAMP Response Elements

1995 • 89 citations

Memory and behavior: a second generation of genetically modified mice

1997 • 65 citations

Heterosynaptic interactions between UP and LTD in CA1 hippocampal slices

1995 • 64 citations

Regulation of calcineurin phosphatase activity and interaction with the FK-506.FK-506 binding protein complex.

1994 • 63 citations

Peptidyl prolyl cis-trans isomerase activity of cyclophilin A in functional homo-oligomeric receptor expression

1997 • 62 citations

Calcineurin inhibitors, FK506 and cyclosporin A, suppress the NMDA receptor-mediated potentials and LTP, but not depotentiation in the rat hippocampus

1996 • 57 citations

Inhibition of phosphatase 2B prevents expression of hippocampal long-term potentiation

1994 • 48 citations

Enhancement of AMPA‐mediated Synaptic Transmission by the Protein Phosphatase Inhibitor Calyculin A in Rat Hippocampal Slices

1993 • 48 citations

Immunocytochemical localization of phosphatase inhibitor‐1 in rat brain

1991 • 45 citations

Localization of phosphatase inhibitor-1 mRNA in the developing and adult rat brain in comparison with that of protein phosphatase-1 mRNAs

1994 • 37 citations

Memory and behavior.

2011 • 5 citations