Induction of human cytomegalovirus (HCMV)-glycoprotein B (gB)-specific neutralizing antibody and phosphoprotein 65 (pp65)-specific cytotoxic T lymphocyte responses by naked DNA immunization

Tight control of gene expression in mammalian cells by tetracycline-responsive promoters.

1992 • 4,885 citations

Heterologous Protection Against Influenza by Injection of DNA Encoding a Viral Protein

1993 • 2,330 citations

Analysis of the Protein-Coding Content of the Sequence of Human Cytomegalovirus Strain AD169

1990 • 1,280 citations

DNA vaccines: protective immunizations by parenteral, mucosal, and gene-gun inoculations.

1993 • 1,122 citations

DNA VACCINES

1997 • 977 citations

Potential Role of Human Cytomegalovirus and p53 Interaction in Coronary Restenosis

1994 • 750 citations

The human cytotoxic T-lymphocyte (CTL) response to cytomegalovirus is dominated by structural protein pp65: frequency, specificity, and T-cell receptor usage of pp65-specific CTL

1996 • 711 citations

Cytotoxic T-lymphocyte response to cytomegalovirus after human allogeneic bone marrow transplantation: pattern of recovery and correlation with cytomegalovirus infection and disease

1991 • 686 citations

Different T helper cell types and antibody isotypes generated by saline and gene gun DNA immunization.

1997 • 566 citations

Intradermal gene immunization: the possible role of DNA uptake in the induction of cellular immunity to viruses.

1994 • 550 citations

Preferential induction of a Th1 immune response and inhibition of specific IgE antibody formation by plasmid DNA immunization.

1996 • 524 citations

Association between Prior Cytomegalovirus Infection and the Risk of Restenosis after Coronary Atherectomy

1996 • 446 citations

Protection against a lethal influenza virus challenge by immunization with a haemagglutinin-expressing plasmid DNA

1993 • 432 citations

Vaccination with a Plasmid Vector Carrying the Rabies Virus Glycoprotein Gene Induces Protective Immunity against Rabies Virus

1994 • 393 citations

Identification of the major late human cytomegalovirus matrix protein pp65 as a target antigen for CD8⁺ virus‐specific cytotoxic T lymphocytes

1994 • 359 citations

Bovine herpesvirus 1: immune responses in mice and cattle injected with plasmid DNA

1993 • 344 citations

Genetic immunization against herpes simplex virus. Protection is mediated by CD4+ T lymphocytes.

1995 • 333 citations

Preclinical efficacy of a prototype DNA vaccine: Enhanced protection against antigenic drift in influenza virus

1995 • 325 citations

Cell surface expression of human cytomegalovirus (HCMV) gp55-116 (gB): use of HCMV-recombinant vaccinia virus-infected cells in analysis of the human neutralizing antibody response

1990 • 316 citations

DNA-mediated immunization to the hepatitis B surface antigen in mice: aspects of the humoral response mimic hepatitis B viral infection in humans.

1995 • 266 citations

Simian immunodeficiency virus DNA vaccine trial in macaques

1996 • 240 citations

Class I MHC-restricted cytotoxic T lymphocyte recognition of cells infected with human cytomegalovirus does not require endogenous viral gene expression.

1991 • 235 citations

Nucleic acid vaccination primes hepatitis B virus surface antigen-specific cytotoxic T lymphocytes in nonresponder mice

1995 • 214 citations

Neutralizing antibodies detect a disulfide-linked glycoprotein complex within the envelope of human cytomegalovirus

1984 • 195 citations

ASSOCIATION BETWEEN PRIOR CYTOMEGALOVIRUS INFECTION AND THE RISK OF RESTENOSIS AFTER CORONARY ATHERECTOMY

1996 • 195 citations

DNA immunization confers protection against lethal lymphocytic choriomeningitis virus infection

1995 • 185 citations

Immunization with DNA vaccines encoding glycoprotein D or glycoprotein B, alone or in combination, induces protective immunity in animal models of herpes simplex virus-2 disease.

1996 • 163 citations

DNA Immunization against Experimental Genital Herpes Simplex Virus Infection

1996 • 157 citations

Protection of ferrets against influenza challenge with a DNA vaccine to the haemagglutinin

1994 • 156 citations

DNA-based immunization with chimeric vectors for the induction of immune responses against the hepatitis C virus nucleocapsid

1995 • 154 citations

Antibodies to Recombinant-Derived Glycoprotein B after Natural Human Cytomegalovirus Infection Correlate with Neutralizing Activity

1992 • 154 citations

Long-Term Anti-Nucleoprotein Cellular and Humoral Immunity Is Induced by Intramuscular Injection of Plasmid DNA Containing NP Gene

1993 • 150 citations

Use of DNAs Expressing HIV-1 Env and Noninfectious HIV-1 Particles to Raise Antibody Responses in Mice

1995 • 148 citations

DNA vaccination against persistent viral infection

1995 • 147 citations

A Qualitative Progression in HIV Type 1 Glycoprotein 120-Specific Cytotoxic Cellular and Humoral Immune Responses in Mice Receiving a DNA-Based Glycoprotein 120 Vaccine

1994 • 143 citations

DNA-Mediated Immunization in Mice Induces a Potent MHC Class I-Restricted Cytotoxic T Lymphocyte Response to the Hepatitis B Envelope Protein

1995 • 142 citations

DNA immunization induces antibody and cytotoxic T cell responses to hepatitis B core antigen in H-2b mice.

1996 • 135 citations

Complexity of the cytokine and antibody response elicited by immunizing mice with Plasmodium yoelii circumsporozoite protein plasmid DNA.

1995 • 126 citations

Protective CTL-dependent immunity and enhanced immunopathology in mice immunized by particle bombardment with DNA encoding an internal virion protein.

1995 • 109 citations

Viral polypeptides detected by a complement-dependent neutralizing murine monoclonal antibody to human cytomegalovirus

1985 • 99 citations

DNA immunization confers protection against murine cytomegalovirus infection

1996 • 95 citations

Human cytomegalovirus structural proteins

1994 • 84 citations

Isolated gA/gB glycoprotein complex of human cytomegalovirus envelope induces humoral and cellular immune-responses in human volunteers

1990 • 79 citations

Preclinical evaluation of an ALVAC (canarypox)-human cytomegalovirus glycoprotein B vaccine candidate

1995 • 67 citations

Cytomegalovirus and atherosclerosis

1995 • 56 citations

A rapid microneutralization assay for cytomegalovirus

1986 • 54 citations

High expression of human cytomegalovirus (HCMV)-gB protein in cells infected with a vaccinia-gB recombinant: the importance of the gB protein in HCMV immunity

1991 • 50 citations

Formulation Of An Immunogenic Human Cytomegalovirus Vaccine: Responses In Mice

1995 • 50 citations

An Adenovirus Recombinant that Expresses the Human Cytomegalovirus Major Envelope Glycoprotein and Induces Neutralizing Antibodies

1990 • 48 citations

Epitope analysis of human cytomegalovirus glycoprotein complexes using murine monoclonal antibodies

1988 • 44 citations

Epitope-Specific Distribution of IgG Subclasses against Antigenic Domains on Glycoproteins of Human Cytomegalovirus

1994 • 40 citations

A Major Neutralizing Domain Maps within the Carboxyl-terminal Half of the Cleaved Cytomegalovirus B Glycoprotein

1989 • 38 citations

The IgG Subclass Responses to Influenza Virus Haemagglutinin in the Mouse: Effect of Route of Inoculation

1989 • 34 citations

Direct DNA immunization of mice with plasmid DNA encoding the tegument protein pp65 (ppUL83) of human cytomegalovirus induces high levels of circulating antibody to the encoded protein.

1995 • 31 citations

Murine cytotoxic T cell response specific for human cytomegalovirus glycoprotein B (gB) induced by adenovirus and vaccinia virus recombinants expressing gB

1993 • 26 citations

Preparation of human monoclonal antibodies against a cytomegalovirus glycoprotein complex of 130 and 55 kDa

1990 • 13 citations

Deleted Work

1955 • 0 citations