Preferential induction of a Th1 immune response and inhibition of specific IgE antibody formation by plasmid DNA immunization.

TH1 and TH2 Cells: Different Patterns of Lymphokine Secretion Lead to Different Functional Properties

1989 • 7,558 citations

Direct Gene Transfer into Mouse Muscle in Vivo

1990 • 3,985 citations

Development of T _H 1 CD4 ⁺ T Cells Through IL-12 Produced by Listeria -Induced Macrophages

1993 • 3,140 citations

Heterologous Protection Against Influenza by Injection of DNA Encoding a Viral Protein

1993 • 2,330 citations

T-Lymphocyte Recognition of Antigen in Association with Gene Products of the Major Histocompatibility Complex

1985 • 942 citations

Regulation of Immunity to Parasites by T Cells and T Cell-Derived Cytokines

1992 • 843 citations

Evidence for compartmentalization of functional subsets of CD2+ T lymphocytes in atopic patients.

1990 • 807 citations

B cell stimulatory factor-1 enhances the IgE response of lipopolysaccharide-activated B cells.

1986 • 797 citations

Gene inoculation generates immune responses against human immunodeficiency virus type 1.

1993 • 655 citations

Removal of endotoxin from protein solutions by phase separation using triton X-114

1990 • 584 citations

Intradermal gene immunization: the possible role of DNA uptake in the induction of cellular immunity to viruses.

1994 • 550 citations

Production of interferon gamma, interleukin 2, interleukin 4, and interleukin 10 by CD4+ lymphocytes in vivo during healing and progressive murine leishmaniasis.

1991 • 528 citations

Generation of polarized antigen-specific CD8 effector populations: reciprocal action of interleukin (IL)-4 and IL-12 in promoting type 2 versus type 1 cytokine profiles.

1994 • 527 citations

Priming immunization determines T helper cytokine mRNA expression patterns in lungs of mice challenged with respiratory syncytial virus.

1993 • 397 citations

Suppression of in vivo polyclonal IgE responses by monoclonal antibody to the lymphokine B-cell stimulatory factor 1.

1986 • 355 citations

Genetic immunization against herpes simplex virus. Protection is mediated by CD4+ T lymphocytes.

1995 • 333 citations

Profiles of lymphokine activities and helper function for IgE in human T cell clones

1988 • 204 citations

Characterization of antigen-specific CD4+ effector T cells in vivo: immunization results in a transient population of MEL-14-, CD45RB- helper cells that secretes interleukin 2 (IL-2), IL-3, IL-4, and interferon gamma.

1991 • 179 citations

Virally induced modulation of murine IgG antibody subclasses.

1988 • 162 citations

Control of Acute Cutaneous Herpes Simplex Virus Infection: T Cell-Mediated Viral Clearance Is Dependent upon Interferon-γ (IFN-γ)

1994 • 156 citations

CD4+ T cell subsets. Lymphokine secretion of memory cells and of effector cells that develop from precursors in vitro.

1990 • 141 citations

IL-12 is expressed and released by human keratinocytes and epidermoid carcinoma cell lines.

1994 • 116 citations

Changes in the precursor frequencies of IL-4 and IFN-gamma secreting CD4+ cells correlate with resolution of lesions in murine cutaneous leishmaniasis.

1992 • 104 citations

The polyclonal and antigen-specific IgE and IgG subclass response of mice injected with ovalbumin in alum or complete Freund's adjuvant

1989 • 89 citations

Concomitant immunoglobulin E and immunoglobulin G1 formation in Nippostrongylus brasiliensis-infected mice.

1987 • 48 citations