Supplementation with Vitamin E and/or Zinc does not Attenuate Atherosclerosis in Apolipoprotein E-deficient Mice fed a High-Fat, High-Cholesterol Diet

Superoxide Dismutase

1969 • 12,578 citations

The pathogenesis of atherosclerosis: a perspective for the 1990s

1993 • 10,730 citations

Role of oxidized low density lipoprotein in atherogenesis.

1991 • 2,691 citations

The role of lipid peroxidation and antioxidants in oxidative modification of LDL

1992 • 2,335 citations

Atherosclerosis: Basic Mechanisms

1995 • 1,697 citations

The oxidation hypothesis of atherosclerosis

1994 • 1,418 citations

Quantitative assessment of atherosclerotic lesions in mice

1987 • 957 citations

Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cells.

1992 • 897 citations

The Yin and Yang of Oxidation in the Development of the Fatty Streak

1996 • 705 citations

Quantitation of atherosclerosis in murine models: correlation between lesions in the aortic origin and in the entire aorta, and differences in the extent of lesions between sexes in LDL receptor-deficient and apolipoprotein E-deficient mice

1995 • 518 citations

Vitamin E suppresses isoprostane generation in vivo and reduces atherosclerosis in ApoE-deficient mice

1998 • 509 citations

ApoE-deficient mice are a model of lipoprotein oxidation in atherogenesis. Demonstration of oxidation-specific epitopes in lesions and high titers of autoantibodies to malondialdehyde-lysine in serum.

1994 • 498 citations

The Effect of α-Tocopherol Supplementation on LDL Oxidation

1995 • 378 citations

Antioxidant and prooxidant activity of alpha-tocopherol in human plasma and low density lipoprotein.

1996 • 212 citations

Spontaneous decay of oxidized ascorbic acid (dehydro-L-ascorbic acid) evaluated by high-pressure liquid chromatography

1990 • 174 citations

Antioxidant-Like Properties of Zinc in Activated Endothelial Cells

1999 • 152 citations

Lipoprotein lipase in human plasma is mainly inactive and associated with cholesterol-rich lipoproteins

1993 • 150 citations

Paradoxical enhancement of atherosclerosis by probucol treatment in apolipoprotein E-deficient mice.

1997 • 132 citations

Antiatherogenic properties of zinc: Implications in endothelial cell metabolism

1996 • 130 citations

Dissociation of atherogenesis from aortic accumulation of lipid hydro(pero)xides in Watanabe heritable hyperlipidemic rabbits

1999 • 113 citations

Effect of the Antioxidant N,N′ -Diphenyl 1,4-Phenylenediamine (DPPD) on Atherosclerosis in ApoE-Deficient Mice

1995 • 106 citations

Inhibition by a coantioxidant of aortic lipoprotein lipid peroxidation and atherosclerosis in apolipoprotein E and low density lipoprotein receptor gene double knockout mice

1999 • 99 citations

Overexpression of Human Superoxide Dismutase Inhibits Oxidation of Low-Density Lipoprotein by Endothelial Cells

1998 • 94 citations

Site-Specific Antiatherogenic Effect of Probucol in Apolipoprotein E–Deficient Mice

2000 • 93 citations

Effect of temperature and phase transition on oxidation resistance of low density lipoprotein.

1996 • 92 citations

Low-Cholesterol and High-Fat Diets Reduce Atherosclerotic Lesion Development in ApoE-Knockout Mice

1999 • 92 citations

The value of apolipoprotein E knockout mice for studying the effects of dietary fat and cholesterol on atherogenesis

2000 • 83 citations

Plasma LDL Oxidation Leads to Its Aggregation in the Atherosclerotic Apolipoprotein E-Deficient Mice

1997 • 83 citations

Relationship between hepatic lipid peroxidation and fibrogenesis in carbon tetrachloride-treated rats: effect of zinc administration

1992 • 76 citations

How different constituents of human plasma and low density lipoprotein determine plasma oxidizability by copper

1998 • 70 citations

Dietary β-Carotene and α-Tocopherol Combination Does Not Inhibit Atherogenesis in an ApoE–Deficient Mouse Model

1999 • 59 citations

Time-dependent changes to lipids and antioxidants in plasma and aortas of apolipoprotein E knockout mice

1999 • 58 citations

The oxidation of low density lipoprotein by cells or iron is inhibited by zinc

1994 • 52 citations

Rapid quantification of alpha-tocopherol in plasma and low- and high-density lipoproteins.

1996 • 38 citations

Vitamins C and E Prolong Time to Arterial Thrombosis in Rats

1999 • 38 citations

Radical-induced lipoprotein and plasma lipid oxidation in normal and apolipoprotein E gene knockout (apoE–/–) mice: apoE–/– mouse as a model for testing the role of tocopherol-mediated peroxidation in atherogenesis

1998 • 36 citations

Automated latex agglutination immunoassay of serum ferritin with a centrifugal analyzer

1994 • 33 citations

Dietary Antioxidants Do Not Reduce Fatty Streak Formation in the C57BL/6 Mouse Atherosclerosis Model

1998 • 31 citations

Reduced progression of atherosclerosis in apolipoprotein E-deficient mice with phenylhydrazine-induced anemia

1999 • 30 citations

Hormonal profile and serum zinc levels in uraemic men with gonadal dysfunction undergoing haemodialysis

1985 • 27 citations

Pitfalls of Direct HDL-Cholesterol Measurements in Mouse Models of Hyperlipidemia and Atherosclerosis

1999 • 21 citations