Low-Cholesterol and High-Fat Diets Reduce Atherosclerotic Lesion Development in ApoE-Knockout Mice

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Apolipoprotein E: Cholesterol Transport Protein with Expanding Role in Cell Biology

1988 • 3,984 citations

Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells

1992 • 2,216 citations

Spontaneous Hypercholesterolemia and Arterial Lesions in Mice Lacking Apolipoprotein E

1992 • 2,189 citations

ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree.

1994 • 1,646 citations

Standard Methods for the Analysis of Oils, Fats and Derivatives

1979 • 1,254 citations

Quantitative assessment of atherosclerotic lesions in mice

1987 • 957 citations

Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cells.

1992 • 897 citations

Atherosclerosis in mice lacking apo E. Evaluation of lesional development and progression.

1994 • 632 citations

Mediterranean diet and public health: personal reflections

1995 • 505 citations

Apolipoprotein AI transgene corrects apolipoprotein E deficiency-induced atherosclerosis in mice.

1994 • 372 citations

Epidemiology of triglycerides: A view from Framingham

1992 • 349 citations

Type III Hyperlipoproteinemia Associated with Apolipoprotein E Deficiency

1981 • 272 citations

Estrogen reduces atherosclerotic lesion development in apolipoprotein E-deficient mice.

1996 • 248 citations

Diet-induced atherosclerosis in mice heterozygous and homozygous for apolipoprotein E gene disruption.

1994 • 235 citations

Dietary n-3 polyunsaturated fatty acids prevent the development of atherosclerotic lesions in mice. Modulation of macrophage secretory activities.

1993 • 204 citations

Chylomicronemia due to apolipoprotein CIII overexpression in apolipoprotein E-null mice. Apolipoprotein CIII-induced hypertriglyceridemia is not mediated by effects on apolipoprotein E.

1997 • 192 citations

Lipoprotein lipase in human plasma is mainly inactive and associated with cholesterol-rich lipoproteins

1993 • 150 citations

Diet-induced hypercholesterolemia and atherosclerosis in heterozygous apolipoprotein E-deficient mice

1994 • 149 citations

Apolipoprotein E deficiency in mice: gene replacement and prevention of atherosclerosis using adenovirus vectors.

1995 • 145 citations

Apolipoprotein E and the Apolipoprotein E-Deficient Mouse

1995 • 142 citations

Effect of Dietary Fat Saturation on LDL Oxidation and Monocyte Adhesion to Human Endothelial Cells In Vitro

1996 • 136 citations

Differential effects of dietary fat on the tissue-specific expression of the apolipoprotein A-I gene: relationship to plasma concentration of high density lipoproteins.

1989 • 110 citations

Effects of dietary fats from animal and plant sources on diet-induced fatty streak lesions in C57BL/6J mice

1993 • 101 citations

Susceptibility to atherosclerosis in mice expressing exclusively apolipoprotein B48 or apolipoprotein B100.

1997 • 101 citations

Monounsaturated Fatty Acid–Enriched Diet Decreases Plasma Plasminogen Activator Inhibitor Type 1

1996 • 95 citations

Tamoxifen Decreases Cholesterol Sevenfold and Abolishes Lipid Lesion Development in Apolipoprotein E Knockout Mice

1997 • 94 citations

Receptors for triglyceride-rich lipoproteins and their role in lipoprotein metabolism

1995 • 84 citations

Epidemiology of triglycerides, small dense low-density lipoprotein, and lipoprotein(a) as risk factors for coronary heart disease

1994 • 81 citations

Dietary polyunsaturated fat modifies low-density lipoproteins and reduces atherosclerosis of nonhuman primates with high and low diet responsiveness

1995 • 65 citations

HDL Deficiency in Genetically Engineered Mice Requires Elevated LDL to Accelerate Atherogenesis

1997 • 52 citations

Profound induction of hepatic cholesteryl ester transfer protein transgene expression in apolipoprotein E and low density lipoprotein receptor gene knockout mice. A novel mechanism signals changes in plasma cholesterol levels.

1996 • 47 citations

In vivo cholesterol kinetics in apolipoprotein E-deficient and control mice.

1995 • 32 citations

The role of lipoprotein lipase and apoprotein E in the recognition of chylomicrons and chylomicron remnants by cultured isolated mouse hepatocytes

1996 • 16 citations

Differential effect of dietary fat saturation and cholesterol on hepatic apolipoprotein gene expression in rats

1994 • 15 citations

Hepatic clearance of chylomicron remnants m mice lacking apoprotein E

1994 • 13 citations